Dr Callum Kaye

Dr Callum Kaye
Dr Callum Kaye
Dr Callum Kaye

MBChB, PhD, FRCA, FFICM

Honorary Clinical Senior Lecturer

About

Biography

Dr. Callum Kaye is a Consultant in Anaesthetics and Intensive Care Medicine at NHS Grampian, based at Aberdeen Royal Infirmary, and an Honorary Clinical Senior Lecturer at the University of Aberdeen.  

Dr. Kaye completed his undergraduate medical training at the University of Aberdeen, followed by Foundation Training in North Scotland. He subsequently pursued clinical training in Anaesthesia and Intensive Care Medicine in West Yorkshire, Inverness and Aberdeen.

After qualifying as a Consultant, Dr. Kaye was awarded an NRS Career Researcher Fellowship, during which he completed a PhD focusing on a programme of work in traumatic brain injury. His research interests remain rooted in critical care medicine, with a particular emphasis on the acute management of brain-injured patients, cardiac arrest and ventilation. Dr. Kaye also leads a national network supporting best practices for brain injury care in Scotland.  

Outside of medicine, Dr. Kaye is an active leader in Scouting, holding National and International leadership roles. He currently serves as a member of the World Scout Committee.

Qualifications

  • MBChB Medicine and Surgery 
    2008 - University of Aberdeen 
  • PhD Health Services Research 
    2024 - University of Aberdeen 

Memberships and Affiliations

Internal Memberships
  • School Ethics Review Board, Member
  • Clinical Studies Oversight Group, Deputy Chair 
External Memberships
  • Fellow of the Royal College of Anaesthetists (FRCA)
  • Fellow of the Faculty of Intensive Care Medicine (FFICM)

Latest Publications

  • Assessment of depth of sedation using Bispectral Index™ monitoring in patients with severe traumatic brain injury in UK intensive care units

    Kaye, C., Rhodes, J., Austin, P., Casey, M., Gould, R., Sira, J., Treweek, S., MacLennan, G.
    BJA Open, vol. 10, 100287
    Contributions to Journals: Articles
  • Use of protracted CPAP as supportive treatment for COVID-19 pneumonitis and associated outcomes: a national cohort study

    Puxty, K. A., Blayney, M., Kaye, C., McPeake, J., Stewart, N., Paton, M., Hall, R., Donaldson, L., Lone, N.
    British Journal of Anaesthesia, vol. 131, no. 3, pp. 617-625
    Contributions to Journals: Articles
  • Utilization of mechanical power and associations with clinical outcomes in brain injured patients: a secondary analysis of the extubation strategies in neuro-intensive care unit patients and associations with outcome (ENIO) trial

    Wahlster, S., Sharma, M., Taran, S., Town, J. A., Stevens, R. D., Cinotti, R., Asehoune, K., Pelosi, P., Robba, C., Abback, P. s., Codorniu, A., Citerio, G., Sala, V. L., Astuto, M., Tringali, E., Alampi, D., Rocco, M., Maugeri, J. G., Bellissima, A., Filippini, M., Lazzeri, N., Cortegiani, A., Ippolito, M., Battaglini, D., Biston, P., Al-Gharyani, M. F., Chabanne, R., Astier, L., Soyer, B., Gaugain, S., Zimmerli, A., Pietsch, U., Filipovic, M., Brandi, G., Bicciato, G., Serrano, A., Monleon, B., van Vliet, P., Gerretsen, B. M., Ortiz-Macias, I. X., Oto, J., Enomoto, N., Matsuda, T., Masui, N., Garçon, P., Zarka, J., Vermeijden, W. J., Cornet, A. D., Inurrigarro, S. R., Domínguez, R. C. L., ENIO Study Group Collaborators, Kaye, C.
    Critical Care, vol. 27, no. 1, 156
    Contributions to Journals: Articles
  • Developing expert international consensus statements for opioid-sparing analgesia using the Delphi method

    Sng, D. D. D., Uitenbosch, G., de Boer, H. D., Carvalho, H. N., Cata, J. P., Erdoes, G., Heytens, L., Lois, F. J., Pelosi, P., Rousseau, A. F., Forget, P., Nesvadba, D., Abdolmohammadi, S., Asfaw, G., Benhamou, D., Blaise, G., Cuvillon, P., Tahan, M. E., Feldano, E., Fettes, P., Finco, G., Fitzpatrick, M., Kapila, A., Kaye, C., Kaura, V., May, H., Meybohm, P., Stamer, U., Taylor, D., Van De Velde, M., Van Pee, B., Pain AND Opioids after Surgery (PANDOS) European Society of Anaesthesiology, Intensive Care (ESAIC) Research Group
    BMC Anesthesiology, vol. 23, no. 1, 62
    Contributions to Journals: Articles
  • Whole-genome sequencing reveals host factors underlying critical COVID-19

    Kousathanas, A., Pairo-Castineira, E., Rawlik, K., Stuckey, A., Odhams, C. A., Walker, S., Russell, C. D., Malinauskas, T., Wu, Y., Millar, J., Shen, X., Elliott, K. S., Griffiths, F., Oosthuyzen, W., Morrice, K., Keating, S., Wang, B., Rhodes, D., Klaric, L., Zechner, M., Parkinson, N., Siddiq, A., Goddard, P., Donovan, S., Maslove, D., Nichol, A., Semple, M. G., Zainy, T., Maleady-Crowe, F., Todd, L., Salehi, S., Knight, J., Elgar, G., Chan, G., Arumugam, P., Patch, C., Rendon, A., Bentley, D., Kingsley, C., Kosmicki, J. A., Horowitz, J. E., Baras, A., Abecasis, G. R., Ferreira, M. A., Justice, A., Mirshahi, T., Oetjens, M., Rader, D. J., Ritchie, M. D., Verma, A., GenOMICC investigators, 23andMe investigators, COVID-Human Genetics Initiative, Kaye, C., Caulfield, M., Baillie, J. K.
    Nature, vol. 607, no. 7917, pp. 97-103
    Contributions to Journals: Articles

View My Publications

Research

Research Overview

Dr Kaye's research focuses on improving outcomes in Critical Care, with particular interests in severe traumatic brain injury (TBI), clinical trial methodology, and inclusive patient and public involvement (PPI).  

Dr Kaye has a specific interest in the use of processed EEG (electroencephalography) to guide sedative use in patients with TBI. His work explores how EEG monitoring can optimise sedation management, balancing the need for patient comfort while supporting neurological recovery. This research aims to enhance brain injury care by minimising the risks of over-sedation or under-sedation, both of which can negatively impact patient outcomes.  

Another key focus of Dr Kaye’s research is emergency consent and recruitment into clinical trials involving critically ill patients. Recognising the challenges posed by time-sensitive interventions and patients lacking capacity, he is keen to raise the profile of this issue, particularly with regard to non-CTIMP trials in Scotland. This work aims to ensure that ethical and efficient consent processes are in place to facilitate high-quality research while respecting patient autonomy in the context of acute care.

Dr Kaye is also committed to advancing inclusive patient and public involvement (PPI) in critical care research. He works to engage a diverse range of patients, families, and communities, ensuring their voices shape study design, delivery, and outcomes. By fostering inclusivity, he aims to make research more relevant, accessible, and impactful for those it seeks to benefit.  

Through his focus on TBI, ethical trial recruitment, and inclusive research practices, Dr Kaye continues to drive innovation in critical care medicine and patient-centred research.

Publications

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  • Assessment of depth of sedation using Bispectral Index™ monitoring in patients with severe traumatic brain injury in UK intensive care units

    Kaye, C., Rhodes, J., Austin, P., Casey, M., Gould, R., Sira, J., Treweek, S., MacLennan, G.
    BJA Open, vol. 10, 100287
    Contributions to Journals: Articles
  • Use of protracted CPAP as supportive treatment for COVID-19 pneumonitis and associated outcomes: a national cohort study

    Puxty, K. A., Blayney, M., Kaye, C., McPeake, J., Stewart, N., Paton, M., Hall, R., Donaldson, L., Lone, N.
    British Journal of Anaesthesia, vol. 131, no. 3, pp. 617-625
    Contributions to Journals: Articles
  • Utilization of mechanical power and associations with clinical outcomes in brain injured patients: a secondary analysis of the extubation strategies in neuro-intensive care unit patients and associations with outcome (ENIO) trial

    Wahlster, S., Sharma, M., Taran, S., Town, J. A., Stevens, R. D., Cinotti, R., Asehoune, K., Pelosi, P., Robba, C., Abback, P. s., Codorniu, A., Citerio, G., Sala, V. L., Astuto, M., Tringali, E., Alampi, D., Rocco, M., Maugeri, J. G., Bellissima, A., Filippini, M., Lazzeri, N., Cortegiani, A., Ippolito, M., Battaglini, D., Biston, P., Al-Gharyani, M. F., Chabanne, R., Astier, L., Soyer, B., Gaugain, S., Zimmerli, A., Pietsch, U., Filipovic, M., Brandi, G., Bicciato, G., Serrano, A., Monleon, B., van Vliet, P., Gerretsen, B. M., Ortiz-Macias, I. X., Oto, J., Enomoto, N., Matsuda, T., Masui, N., Garçon, P., Zarka, J., Vermeijden, W. J., Cornet, A. D., Inurrigarro, S. R., Domínguez, R. C. L., ENIO Study Group Collaborators, Kaye, C.
    Critical Care, vol. 27, no. 1, 156
    Contributions to Journals: Articles
  • Developing expert international consensus statements for opioid-sparing analgesia using the Delphi method

    Sng, D. D. D., Uitenbosch, G., de Boer, H. D., Carvalho, H. N., Cata, J. P., Erdoes, G., Heytens, L., Lois, F. J., Pelosi, P., Rousseau, A. F., Forget, P., Nesvadba, D., Abdolmohammadi, S., Asfaw, G., Benhamou, D., Blaise, G., Cuvillon, P., Tahan, M. E., Feldano, E., Fettes, P., Finco, G., Fitzpatrick, M., Kapila, A., Kaye, C., Kaura, V., May, H., Meybohm, P., Stamer, U., Taylor, D., Van De Velde, M., Van Pee, B., Pain AND Opioids after Surgery (PANDOS) European Society of Anaesthesiology, Intensive Care (ESAIC) Research Group
    BMC Anesthesiology, vol. 23, no. 1, 62
    Contributions to Journals: Articles
  • Whole-genome sequencing reveals host factors underlying critical COVID-19

    Kousathanas, A., Pairo-Castineira, E., Rawlik, K., Stuckey, A., Odhams, C. A., Walker, S., Russell, C. D., Malinauskas, T., Wu, Y., Millar, J., Shen, X., Elliott, K. S., Griffiths, F., Oosthuyzen, W., Morrice, K., Keating, S., Wang, B., Rhodes, D., Klaric, L., Zechner, M., Parkinson, N., Siddiq, A., Goddard, P., Donovan, S., Maslove, D., Nichol, A., Semple, M. G., Zainy, T., Maleady-Crowe, F., Todd, L., Salehi, S., Knight, J., Elgar, G., Chan, G., Arumugam, P., Patch, C., Rendon, A., Bentley, D., Kingsley, C., Kosmicki, J. A., Horowitz, J. E., Baras, A., Abecasis, G. R., Ferreira, M. A., Justice, A., Mirshahi, T., Oetjens, M., Rader, D. J., Ritchie, M. D., Verma, A., GenOMICC investigators, 23andMe investigators, COVID-Human Genetics Initiative, Kaye, C., Caulfield, M., Baillie, J. K.
    Nature, vol. 607, no. 7917, pp. 97-103
    Contributions to Journals: Articles
  • Biomarkers for assessing acute kidney injury for people who are being considered for admission to critical care: a systematic review and cost-effectiveness analysis

    Brazzelli, M., Aucott, L., Aceves Martins, M., Robertson, C., Jacobsen, E., Imamura, M., Poobalan, A., Manson, P., Scotland, G., Kaye, C., Sawhney, S., Boyers, D.
    Health Technology Assessment, vol. 26, no. 7, pp. 1-286
    Contributions to Journals: Articles
  • Cost-effectiveness and value of information analysis of NephroCheck and NGAL tests compared to standard care for the diagnosis of acute kidney injury

    Jacobsen, E., Sawhney, S., Brazzelli, M., Aucott, L., Scotland, G., Aceves Martins, M., Robertson, C., Imamura, M., Poobalan, A., Manson, P., Kaye, C., Boyers, D.
    BMC Nephrology, vol. 22, 399
    Contributions to Journals: Articles
  • Vasoactive agents in acute mesenteric ischaemia in critical care.  A systematic review [version 2; peer review: 1 approved, 2 approved with reservations]

    Brennan, C. A., Osei-Bonsu, P., McClenaghan, R. E., Nassar, A., Forget, P., Kaye, C., Ramsay, G.
    F1000Research, vol. 10, 453
    Contributions to Journals: Articles
  • Extubation strategies in neuro-intensive care unit patients and associations with outcomes: the ENIO multicentre international observational study

    Kaye, C.
    Annals of Translational Medicine
    Contributions to Journals: Articles
  • Multiple organ dysfunction after trauma

    Kaye, C.
    British Journal of Surgery
    Contributions to Journals: Articles