Dr W HUANG

Dr W HUANG
Dr W HUANG

Dr W HUANG

Senior Lecturer

Accepting PhDs

About

Room 5.26
Institute of Medical Sciences
University of Aberdeen
Foresterhill, Aberdeen
Scotland, AB25 2ZD. 

Biography

Current post:
Senior Lecturer
Institute of Medical Sciences
University of Aberdeen

Previous posts:
Senior Research Scientist
Imperial College London

Memberships and Affiliations

Internal Memberships

Dr Huang involves in the following Administration duties:

•   IMS MCI seminar organisor: Invitation of seminar speakers and organisation of seminars
•   Provide scientific and career advice to BSc Honours, Master and PhD students
•   Provide pastoral care to more than 10 personal tutees at UoA
•   Act as academic advisors/examiners for PhD students of other academic staff
•   Act as a mentor to post-doctoral staff in university’s mentoring scheme
•   Manage the social media accounts for the Aberdeen Spinal Injury Research Team  (ASIRT)
•   Organise and participate in various fundraising activities on behalf of the ASIRT

•   Member of the Dignity at Work and Study Working Group of UoA

•   Member of the PGT Good Cause Committee, School of Medicine, Medical Science & Nutirion

 

External Memberships

Dr Huang is the Treasurer of Non Human Pain Special Interest Group (SIG) at the International Association for the Study of Pain (IASP).

Dr Huang is an Associate Editor of BMJ Open Science.

Dr Huang is an Editor of Current Trends In Medical & Biological Engineering.

Research

Research Overview

The World Health Organization states that every year between 250,000 and 500,000 people around the world suffer a spinal cord injury. In the UK, about 50,000 people live with spinal cord injury, with about 1,000 new cases each year. Spinal cord injury can cause permanent loss of nerve function below the level of injury. There is no cure. The estimated annual cost to the NHS is around £1 billion. Current treatments focus on limiting the extent of damage and helping patients manage the injury and subsequent dramatic lifestyle changes. The lack of therapies for spinal cord injury creates a substantial, unmet, clinical need for millions of patients. Our group aims to develop novel approaches to improve function recovery after spinal cord injury, and we are pursuing the following two research areas:

A Combinatorial Approach For Spinal Cord Repair
Based on our previous experience using novel biomaterials for peripheral nerve repair, my group is focusing on the development of a biomaterial-based combinatorial approach to promote axon regeneration and function recovery after spinal cord injury using relevant in vitro, ex vivo and animal models. In collaboration with colleagues here at Aberdeen and elsewhere, we are developing novel combinatorial strategies including the use of suitable novel biomaterials, novel growth-promoting biomolecules, and electric stimulation for spinal cord repair.

Central Neuropathic Pain After Spinal Cord Injury
My group has a strong interest in the role of neuroinflammation in the development and maintenance of central neuropathic pain following spinal cord injury. We aim to develop novel strategies to target this neuroinflammation in order to prevent and/or treat this common complication that significantly impacts on the quality of life of millions spinal injured patients. We are world leaders in using ethologically relevant and pain-related complex rodent behaviours and outcome measures to facilitate the development of novel analgesics for central neuropathic pain after spinal cord injury.

Research Areas

Accepting PhDs

I am currently accepting PhDs in Biomedical Sciences.


Please get in touch if you would like to discuss your research ideas further.

Email Me

Biomedical Sciences

Supervising
Accepting PhDs

Research Specialisms

  • Neuroscience
  • Tissue Engineering and Regenerative Medicine

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Collaborations

In Aberdeen:

  • Dr Huang is part of the Aberdeen Spinal Injury Research Team and actively collaborates with other Team members to develop novel strategies for spinal cord repair.
  • Collaboration with Profs Roger Pertwee and Helen Galley on various projects.

Outside Aberdeen: Dr Huang actively collaborate with national and international leading experts.

Industrial collaboration:

  • Oxford Biomaterials Ltd., Oxford, England
  • Biogelx Ltd., Scotland
  • Cell Guidance Systems, Cambridge

Supervision

My current supervision areas are: Biomedical Sciences.

Current PhD students:

Dominik Domanski (1st year)

Abigail Dos Santos (1st year)

Aya Abdallah (2nd year)

William Macintosh-Smith (2 year)

Mindaugas Viskontas (2 year)

Yuting Wei (submitted thesis, waiting for viva)

Past PhD students:

Anna Varone (graduated 2019)

Alba Guijarro-Belmar (gradudated 2019)

Marieta Georgieva (graduated 2018)

 

Funding and Grants

Current Research Income:

Research Grants (total £563K since 2017):

• Scottish Rugby Union/private donation, 2019-22
• Aberdeen University Development Trust, 2016-22
• BJA/RCoA PhD studentship, 2020-2023
• Medical Research Scotland(MRS)/Biogelx Ltd. PhD studentship, 2019-2023
• Two Elphinstone PhD Scholarships, 2020-2023
• International PhD studentship, 2016-20

Our research is kindly supported by:

Previous Grants:

• Institute of Medical Sciences PhD Studentship, 2014-19
• International Spinal Research Trust PhD Studentship, 2015-19
• Aberdeen University Development Trust PhD Studentship, 2014-18
• Aberdeen University Development Trust, 2016-19
• Tenovus Scotland, 2016-17
• RS McDonald Trust, 2014-17
• Scottish Rugby Union, Research Grant, 2013-16
• Development Trust, Equipment Grant, 2013-16
• Medical Research Scotland Vacation Scholarship, 06-08/2015
• Medical Research Scotland Vacation Scholarship, 06-08/2016
• Wellcome Trust Vacation Scholarship, 06-08/2016
• Aberdeen University Start-up, 2013-2016
• National Institute of Academic Anaesthesia, 2013-14
• Chelsea & Westminster NHS Trust; 2010-11
• Neurotex Ltd., 2008-9
• Wellcome Trust, International Travelling Research Fellowship, 2001-2

Teaching

Teaching Responsibilities

For the Institute of Medical Sciences:

PGT: MSc IMS Project Course: course coordinator

Level 2
• SM2001: Foundation Skills for Medical Sciences
• SM2501: Research Skills for Medical Sciences

Level 3
• SM3002: Frontiers of Medical Sciences: course coordinator
• SR3508: Clinical Exercise Physiology
• BM3804: Neuroscience Research Topics
• DB3804: Development of Organ Systems

Level 4
• BM4004: Advanced Molecules, Membranes & Cells
• PY4302/AN4302: Developmental Neuroscience

For the Institute of Dentistry:

• BDS 2: Pain Physiology
• BDS 3: Wound Healing

For the Medical School:

• Yr1: tutors on various topics
• Yr1: SSC "Brainstorming": theme leader
• Yr2: tutors on various topics

Supervision of BSc and postgraduate students:

• BSc Honours
• MSc/MRes students
• Principal supervisor of 4 PhD students

Publications

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  • Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations

    Andrews, N. A., Latrémolière, A., Basbaum, A. I., Mogil, J. S., Porreca, F., Rice, A. S. C., Woolf, C. J., Currie, G. L., Dworkin, R. H., Eisenach, J. C., Evans, S., Gewandter, J. S., Gover, T. D., Handwerker, H., Huang, W., Iyengar, S., Jensen, M. P., Kennedy, J. D., Lee, N., Levine, J., Lidster, K., Machin, I., McDermott, M. P., McMahon, S. B., Price, T. J., Ross, S. E., Scherrer, G., Seal, R. P., Sena, E. S., Silva, E., Stone, L., Svensson, C. I., Turk, D. C., Whiteside, G.
    Pain, vol. 157, no. 4, pp. 901-909
    Contributions to Journals: Articles
  • Experimental design and reporting standards for improving the internal validity of pre-clinical studies in the field of pain: Consensus of the IMI-Europain consortium

    Knopp, K. L., Stenfors, C., Baastrup, C., Bannon, A. W., Calvo, M., Caspani, O., Currie, G., Finnerup, N. B., Huang, W., Kennedy, J. D., Lefevre, I., Machin, I., Macleod, M., Rees, H., Rice, A., Rutten, K., Segerdahl, M., Serra, J., Wodarski, R., Berge, O., Treede, R.
    Scandinavian Journal of Pain, vol. 7, pp. 58-70
    Contributions to Journals: Articles
  • Macrophage-sensory neuronal interaction in HIV-1 gp120-induced neurotoxicity

    Moss, P. J., Huang, W., Dawes, J., Okuse, K., McMahon, S., Rice, A.
    British Journal of Anaesthesia, vol. 114, no. 3, pp. 499-508
    Contributions to Journals: Articles
  • Heterogeneous responses of dorsal root ganglion neurons in neuropathies induced by peripheral nerve trauma and the antiretroviral drug stavudine

    Boateng, E. K., Novejarque, A., Pheby, T., Rice, A. S. C., Huang, W.
    European Journal of Pain, vol. 19, no. 2, pp. 236-245
    Contributions to Journals: Articles
  • Short-term effect of acute and repeated urinary bladder inflammation on thigmotactic behaviour in the laboratory rat: [v1; ref status: awaiting peer review, http://f1000r.es/56e] - See more at: http://f1000research.com/articles/4-109/v1#sthash.T4hJEMI2.dpuf

    Morland, R. H., Novejarque, A., Huang, W., Wodarski, R., Denk, F., Dawes, J. D., Pheby, T., McMahon, S. B., Rice, A. S. C.
    F1000 Research, vol. 4, 109
    Contributions to Journals: Articles
  • A characterization of white matter pathology following spinal cord compression injury in the rat

    Ward, R. E., Huang, W., Kostusiak, M., Pallier, P. N., Michael-Titus, A. T., Priestley, J. V.
    Neuroscience, vol. 260, pp. 227-239
    Contributions to Journals: Articles
  • HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain

    Denk, F., Huang, W., Sidders, B., Bithell, A., Crow, M., Grist, J., Sharma, S., Ziemek, D., Rice, A. S. C., Buckley, N. J., McMahon, S. B.
    Pain, vol. 154, no. 9, pp. 1668-1679
    Contributions to Journals: Articles
  • A clinically relevant rodent model of the HIV antiretroviral drug stavudine induced painful peripheral neuropathy

    Huang, W., Calvo, M., Karu, K., Olausen, H. R., Bathgate, G., Okuse, K., Bennett, D. L., Rice, A. S.
    Pain, vol. 154, no. 4, pp. 560-575
    Contributions to Journals: Articles
  • Transparency in the reporting of in vivo pre-clinical pain research: The relevance and implications of the ARRIVE (Animal Research: Reporting In Vivo Experiments) guidelines

    Rice, A. S., Morland, R., Huang, W., Currie, G. L., Sena, E. S., Macleod, M. R.
    Scandinavian Journal of Pain, vol. 4, no. 2, pp. 58-62
    Contributions to Journals: Articles
  • Improved outcome after spinal cord compression injury in mice treated with docosahexaenoic acid

    Lim, S., Huang, W., Hall, J. C. E., Michael-Titus, A. T., Priestley, J. V.
    Experimental Neurology, vol. 239, pp. 13-27
    Contributions to Journals: Articles

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Contributions to Journals