Chair in Medicine & Therapeutics (Clinical)
The University of Aberdeen
School of Medicine, Medical Sciences and Nutrition
University of Aberdeen
Arthritis and Regenerative Medicine Laboratory
Institute of Medical Sciences
Foresterhill, Aberdeen AB25 2ZD
Cosimo graduated in Medicine (maxima cum laude) from the University of Bari (Italy), where he also underwent specialist training in Rheumatology. He then moved to Belgium, where he obtained his PhD from the Catholic University of Leuven and was recipient of the Rotary Young Investigator Award 2003 from the Royal Belgian Society for Rheumatology.
In 2003 Cosimo moved to the UK in the Department of Rheumatology at King's College London. In May 2005 he was awarded a Clinician Scientist Fellowship from the Medical Research Council and in December 2005 he was appointed Clinical Senior Lecturer & Consultant Rheumatologist.
Since September 2007 Cosimo is Professor of Translational Medicine at the University of Aberdeen, where he heads the Arthritis and Regenerative Medicine Laboratory.
Cosimo has expertise in translational stem cell research for musculoskeletal repair, regenerative medicine and tissue engineering. His current research interests focus on the development of novel stem cell-based therapies for the musculoskeletal system, mainly articular cartilage and bone; they also include the study of the resident joint stem cells and their niches in health and diseases such as osteoarthritis and rheumatoid arthritis.
The ultimate goal of Professor De Bari's research programme is the development of novel cell-based therapeutic approaches to skeletal repair. His programme consists of two main areas.
The first is centred on the development and validation of "clinically relevant" assays and surrogate measures of the potency of stem cell preparations, to be used as quality controls for efficacy of stem cell therapies in the clinic.
The second area of investigation aims at characterizing the niches of resident stem cells within the joint environment and studying their molecular regulation in vivo in health and diseases such as osteoarthritis and rheumatoid arthritis. Understanding the roles of stem cells in the pathophysiology of joint homeostasis, remodelling and repair in health and disease will be instrumental for the development of novel therapeutic protocols to trigger and enhance intrinsic joint surface repair by targeting resident stem cells, with the ultimate goal to modify disease outcome and restore a functional joint homeostasis.
- Further Info
Cosimo is an Associate Editor for Osteoarthritis and Cartilage and a member of the editorial board of several journals including Regenerative Medicine. He serves on the Medical Research Council’s Regenerative Medicine Research Committee (RMRC) and on the Fellowships Implementation Committee of Arthritis Research UK.
Cosimo has been a member of the Research & Training Committee of the Osteoarthritis Research Society International (OARSI).