Dr Alexander Lorenz

Dr Alexander Lorenz
Dr Alexander Lorenz

Dr Alexander Lorenz

Senior Lecturer

Accepting PhDs

About

The Institute of Medical Sciences (IMS)

School of Medicine, Medical Sciences & Nutrition

University of Aberdeen

Foresterhill

Aberdeen, AB25 2ZD

United Kingdom

 

Office: IMS, Room 4:20

Lab: IMS, Room 4:08

Biography

Since 2021: Senior Lecturer in Fungal Genetics; School of Medicine, Medical Sciences & Nutrition; University of Aberdeen, UK

2013-2021: Lecturer in Molecular Cell Biology; School of Medicine, Medical Sciences & Nutrition; University of Aberdeen, UK

2007-2013: Postdoctoral Research Associate at the Department of Biochemistry, University of Oxford, UK

2005-2007: Erwin Schrödinger-Fellow of the Austrian Science Fund (FWF) researching at the Department of Biochemistry, University of Oxford, UK

2003-2005: Postdoctoral Research Associate at the Department of Chromosome Biology, University of Vienna, Austria

1992-2003: Studying Botany and Genetics at the University of Vienna, Austria and at the University of Cologne, Germany

Qualifications

  • PhD Genetics 
    2003 - University of Vienna, Austria 
    with distinction
  • MRes Botany 
    2000 - University of Vienna, Austria 
    with distinction

Memberships and Affiliations

Internal Memberships

Since October 2014 Member of and since January 2016 Biological Safety Officer for the Foresterhill Biological Safety Committee

 

External Memberships

Since 2021: Honorary Treasurer of the Genetics Society.

Member of the following learned societies:

BMSBiochemical SocietyGenetics Society UKISHAMMicrobiology Society UK

Associate Editor/Editorial Board Member: Critical Reviews in Microbiology, FEMS Yeast Research, Microbiological Research

Ad hoc reviewer for international research journals: Biomolecules; BMC Genomics; Cellular Microbiology; Chromosoma; Computational and Structural Biotechnology Journal; Current Genetics; Evolution, Medicine & Public Health; FEMS Yeast Research; Folia Microbiologica; Frontiers in Cell and Developmental Biology; Frontiers in Microbiology; Fungal Biology Reviews; G3: Genes|Genomes|Genetics; Gene; Genes; Genetics; Genome; Germs; International Journal of Molecular Sciences; Journal of Cell Science; Journal of Fungi; Journal of Medical Microbiology; Microorganisms; Nature Communications; Nature Structural & Molecular Biology; Nucleic Acids Research; Open Biology; PLoS Genetics; Scientific Reports; Theoretical and Applied Genetics

Publons

Grant reviewer: Academia Sinica|Taiwan, ANR|France, BBSRC|UK, Carnegie Trust for the Universities of Scotland|UK, ERA-CAPS|European Union, Israel Science Foundation|Israel, MRC|UK, NSF|USA, NWO|Netherlands, SRDA-APVV|Slovakia, Wellcome Trust|UK

Research

Research Areas

Accepting PhDs

I am currently accepting PhDs in Biomedical Sciences.


Please get in touch if you would like to discuss your research ideas further.

Email Me

Biomedical Sciences

Supervising
Accepting PhDs

Research Specialisms

  • Genetics
  • Microbiology
  • Mycology

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Current Research

 

 

Past Research

Bravo Ruiz G, Ross ZK, Gow NAR, Lorenz A (2020) Pseudohyphal growth of the emerging pathogen Candida auris is triggered by genotoxic stress through the S phase checkpoint. - mSphere 5 (2): e00151-20 (17pp.)

Brown SD*, Mpaulo SJ*, Asogwa MN, Jézéquel M, Whitby MC, Lorenz A (2019) DNA sequence differences are determinants of meiotic recombination outcome. - Scientific Reports 9: 16446 (10pp.) (*these authors contributed equally)

Bravo Ruiz G, Ross ZK, Holmes E, Schelenz S, Gow NAR, Lorenz A (2019) Rapid and extensive karyotype diversification in haploid clinical Candida auris isolates. - Current Genetics 65 (5): 1217-1228

Lorenz A (2017) Modulation of meiotic homologous recombination by DNA helicases. - Yeast 34 (5): 195-203

Lorenz A, Mehats A, Osman F, Whitby MC (2014) Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination. - Nucleic Acids Research 42 (22): 13723-13735

Lorenz A, Osman F, Sun W, Nandi S, Steinacher R, Whitby MC (2012) The fission yeast FANCM ortholog directs non-crossover recombination during meiosis. - Science (New York, N.Y.) 336 (6088): 1585-1588

 

 Full Publication list with links to PDFs

 

Collaborations

Professor Alistair Brown, MRC Centre for Medical Mycology, School of Biosciences, University of Exeter, UK

Dr Kyuha Choi, POSTECH Biotech Centre, Pohang University of Science and Technology, South Korea

Professor Anne D. Donaldson, Institute of Medical Sciences (IMS), University of Aberdeen, UK

Professor Neil A. R. Gow, MRC Centre for Medical Mycology, School of Biosciences, University of Exeter, UK

Professor Adele Marston, Wellcome Trust Centre for Cell Biology, University of Edinburgh, UK

Dr Bart Nieuwenhuis, Ludwig-Maximilians-Universität München, Germany

Professor Harry Scherthan, Bundeswehr Institute of Radiobiology affiliated with the Universität Ulm, Germany

Professor Neil Vargesson, Institute of Medical Sciences (IMS), University of Aberdeen, UK

Professor Jürgen Wendland, Institute of Microbiology and Biochemistry, University Geisenheim, Germany

Professor Matthew Whitby, Department of Biochemistry, University of Oxford, UK

Supervision

My current supervision areas are: Biomedical Sciences.

Sakinah Alsayegh, PhD in Molecular Microbiology 2019-2023 "Morphogenetic switching and antimicrobial resistance in Candida auris"

Chloe Pelletier, PhD in Medical Mycology 2019-2022 "Stress response and virulence in Candida auris"

Inês Dias Rebelo, MRes in Molecular Biology 2018-2019 "Epigenetics and meiotic recombination in Schizosaccharomyce pombe"

Stefaniya T. Stoichkova, PhD in Microbiology 2017-2022 "Tools for the genetic manipulation of Candida auris"

Samantha J. Mpaulo, PhD in Genetics 2017-2021 "DNA double-strand break formation during meiosis"

Zoe K. Ross, MRes and PhD in Medical Mycology 2017-2020 "Genome analysis of and antimicrobial resistance in Candida auris"

Simon D. Brown, PhD in Genetics 2013-2017 "Meiotic recombination in Schizosaccharomyces pombe"

Funding and Grants

02/2020-09/2020: Seed Corn Fund (with Prof Neil Vargesson) - Institutional Strategic Support Fund, Wellcome Trust

10/2019-10/2022: Award for a 3-year PhD-studentship - Kuwait Cultural Office UK, Ministry of Higher Education, Kuwait

10/2019-10/2022: MRC-CMM award for a 3-year PhD-studentship (with Profs Al Brown & Neil Gow) - MRC & University of Aberdeen, UK

02/2019-07/2019: Research Incentive Grant - The Carnegie Trust for the Universities of Scotland

07/2018-01/2020: Seed Award in Science - Wellcome Trust

01/2018-01/2019: Research Grant - Tenovus Scotland (with Prof Neil Gow)

10/2017-10/2020: MRC-CMM award for a 3-year PhD-studentship (with Prof Neil Gow) - MRC & University of Aberdeen, UK

10/2017-10/2021: IMS award for a 4-year PhD-studentship (with Prof Neil Gow) - University of Aberdeen, UK

10/2017-10/2021: EastBio-DTP awards for two 4-year PhD-studentships (with Prof Adele Marston, University of Edinburgh) - BBSRC

06/2017-11/2017: Seed Corn Fund (with Prof Neil Gow) - Institutional Strategic Support Fund, Wellcome Trust

04/2017: One-off Meeting sponsorship (with Dr Isabelle Colas) for the 9th British Meiosis Meeting in Dundee - Genetics Society UK

06/2016-08/2016: G&D Summer studentship (for Ki Choi CHAN, University of York) - Genetics Society UK

01/2015-09/2015: Research Incentive Grant - The Carnegie Trust for the Universities of Scotland

10/2014-10/2015: Research Grant - Royal Society

10/2013-10/2017: DTG award for a 4-year PhD-studentship - BBSRC & University of Aberdeen, UK

09/2013: Principal’s Excellence Fund - University of Aberdeen

07/2005-07/2007: Erwin Schrödinger-Fellowship - Austrian Science Fund (FWF)

10/1997-06/1998: ERASMUS/SOCRATES-scholarship - European Union

Teaching

Teaching Responsibilities

Course Co-ordination

GN3502 - Genetics

Lecturing

MB3006 - Molecular Biology of the Cell: 'Cell Cycle & Cell Division' (Lectures, Tutorial)

GN3502 - Genetics: 'Mendelian Genetics', 'Chromosome Biology', 'Fungal Genetics' (Lectures)

MC3504 - Molecular Microbiology: 'Fungal Genetics and Biology' (Lectures)

MB4050 - Genome Organisation and Analysis: 'Genome Integrity - DNA Repair, Homologous Recombination, and Meiosis' (Lectures)

Practical

BI20M3 - Molecular Biology of the Gene: 'Restriction Analysis of DNA'

SM2001 - Foundation Skills for Medical Sciences: 'Data Collection and Statistics', 'Experimental Design'

GN3502 - Genetics: 'Analysis of Meiotic Recombination'

Student Supervision

MB4502 - 'Molecular Biology Honours Research Project'

MB5904 - Masters Research Project'

 


 

Non-course Teaching Responsibilities

Personal Tutor for 8 UG students in various degree programmes and at all levels.

Member of 9-months and 24-months PhD student assessment panels.

Publications

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Chapters in Books, Reports and Conference Proceedings

Contributions to Journals