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Advanced Bioinformatics and Genome Sequencing (MB5522)
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15 Credit Points
An exciting course that brings a student right up to date with bioinformatics, genome assembly and annotation technology. You, the student, will analyse the genome of an unknown bacterium from the environment. The genome of this isolate has been extracted and whole genome sequenced. You will assemble your own bacterial genome and functionally annotate it, taught by expert bioinformaticians from our Centre for Genome-Enabled Biology and Medicine. Your analysis will enable you to identify the species you have isolated, produce a full inventory of genes and their presumptive functions, allowing an exploration of the antibiotic resistance potential of the bacteria. Overall, the course prepares a student for future employment in a biosciences' workplace, where genome sequencing, assembly and annotation is becoming an everyday tool of modern biotechnology.
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Advanced Biotechnology with Computation (BT5511)
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15 Credit Points
This course will take the student through in-depth study of how synthetic biology, systems biology and computation are transforming the principles and practice of modern biotechnology. The course will teach modern methods of biotechnology including host cell design and optimisation using modern modelling techniques, leading to an understanding of how multiple genes under precise regulatory control can be introduced into a species to endow it with new biotechnologically valuable properties. The course will demonstrate the application of computer programming to bioinformatic analysis with direct relevance to modern biotechnology.
Through hands on study of synthetic biological processes in a series of workshops, students will learn how advanced genetic engineering of host expression systems can transform production of pharmaceuticals, chemical feedstocks and biofuels. Through workshop study of computer programming, students will gain hands-on knowledge of introductory programming skills relevant to genomic analysis and modern biotechnology. The course will equip students with a range of knowledge and skills directly relevant to modern biosciences, including the biotechnology industry.
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Host - Pathogen Interactions (MB5516)
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15 Credit Points
Why do some microorganisms cause disease, yet others don’t? This course explores host-pathogen interactions from bacterial, fungal, parasite, viral and host perspectives in a lecture series, examining virulence factors, host defences and immune responses.
Students develop a detailed knowledge of one specific host-pathogen interaction through self-directed study and working as a group to review a specific disease selected by the students. In addition, students will enhance their ability to work within teams and will develop their skill in academic writing, creating a group-written review article.
Course workshops discuss experimental design for analysis of host-pathogen interactions, virulence and evaluation of novel drug treatments.
The course materials will enable students to develop and refine their understanding of the roles of host and pathogen in infectious disease.
Please note that some of the material on this course may describe animal research and/or may discuss disease outbreaks.
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Advanced Genomic Tools in Biomedical Research (MB5528)
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15 Credit Points
A course describing the wide range of ways in which genome sequencing has transformed biomedical research and our understanding of human disease.
Contains material detailing a range of examples of advanced genomic tools and technologies and their applications in biomedical science.
A course that makes wide use of the literature, allowing you to read about and understand the latest genomics-based methods.
A course placing a high value on its teaching and learning; lecture material supported by workshops – your chance to put knowledge into practice, ask questions and enjoy the science.
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Genes and Immunity (MB5526)
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15 Credit Points
The genetic basis of self/non-self discrimination underlies all immune responses and can influence disease susceptibility at the level of both individual and populations. This course addresses this topic through lectures from research active experts in the main areas covered.
The course involves students delivering a media presentation on a course-related topic.
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Drug Development to Evidence Based Medicine (MT5520)
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15 Credit Points
This course will provide you with an introduction to evidence-based medicine. It will also include a description of the elements of pharmaceutical research as well as of the drug development process.
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Biologic Drug Discovery (BT5509)
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15 Credit Points
Biologic therapies represent one of the most important and novel areas of drug discovery in the 21st century. The aim of this course is to provide an insight into the success of protein, peptide or antibody based biologic therapies and to examine how this exciting new area will develop over the next decade.
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Applied Developmental Biology (MB5524)
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15 Credit Points
This course will provide a thorough understanding of the mechanisms regulating embryonic and fetal development. Factors influencing normal and abnormal development, including, genes and the environment, will be discussed. The impact of developmental biology upon reproductive and regenerative medicine, including stem cells, cloning, gene editing and genetic manipulation technologies, as well as the ethical considerations, will be evaluated.