MSc (Jagiellonian University, Poland); PhD (Jagiellonian University, Poland)
Lecturer
- About
-
- Email Address
- e.krol@abdn.ac.uk
- Telephone Number
- +44 (0)1224 272883
- School/Department
- School of Biological Sciences
- Research
-
Research Overview
My research interests focus on whole animal energetics and physiology. This framework provides the common theme that links my interests in the role of energy use during both reproduction and the development of obesity.
Current Research
My doctoral work on the energetics of hedgehogs (Jagiellonian University, Poland) and postdoctoral work on reproduction in laboratory mice (University of Aberdeen, Scotland) and deer mice (University of California, Riverside, USA) have resulted in a novel hypothesis that the limits to sustained energy intake at peak lactation are imposed by the capacity of the animal to dissipate body heat. This hypothesis is currently under further investigation.
My obesity related work focuses on the effects of photoperiod on body mass, food intake, body composition, energy balance and hypothalamic gene expression in the field vole, which provides a new animal model for the investigation of seasonal adiposity at both organism and molecular levels. The major finding of this project is that the photoperiod-induced increase in body mass is associated with the up-regulation of the suppressor of cytokine signalling (SOCS3). This appears to act as a desensitisation mechanism that allows animals to ignore elevated leptin levels generated by increased adiposity, leading to an accumulation of body fat without counter-regulatory mechanisms.
- Publications
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Page 1 of 1 Results 1 to 51 of 51
Modulation of gut microbiota composition and predicted metabolic capacity after nutritional programming with a plant-rich diet in Atlantic salmon (Salmo salar): insights across developmental stages
Animal Microbiome, vol. 6, 38Contributions to Journals: ArticlesCan nutritional programming in Atlantic salmon (Salmo salar) be optimised with a reduced stimulus period?
Aquaculture, vol. 585, 740686Contributions to Journals: ArticlesMaternal High Fat Diet in Lactation Impacts Hypothalamic Neurogenesis and Neurotrophic Development, Leading to Later Life Susceptibility to Obesity in Male but Not Female Mice
Advanced science (Weinheim, Baden-Wurttemberg, Germany), vol. 10, no. 35, e2305472Contributions to Journals: ArticlesA Summer Heat Wave Reduced Activity, Heart Rate, and Autumn Body Mass in a Cold-Adapted Ungulate
Physiological and Biochemical Zoology, vol. 96, no. 4, pp. 247-320Contributions to Journals: ArticlesFur removal promotes an earlier expression of involution-related genes in mammary gland of lactating mice
Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology, pp. 171-192Contributions to Journals: ArticlesGill Transcriptomic Responses to Toxin-producing Alga Prymnesium parvum in Rainbow Trout
Frontiers in Immunology, vol. 12, 794593Contributions to Journals: ArticlesDeterminants of heart rate in Svalbard reindeer reveal mechanisms of seasonal energy management
Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 376, no. 1831, 20200215Contributions to Journals: ArticlesFat storage influences fasting endurance more than body size in an ungulate
Functional Ecology, vol. 35, no. 7, pp. 1470-1480Contributions to Journals: ArticlesIntegration of Transcriptome, Gross Morphology and Histopathology in the Gill of Sea Farmed Atlantic Salmon (Salmo salar): Lessons from Multi-site Sampling
Frontiers in Genetics, vol. 11, 610Contributions to Journals: ArticlesPhotoperiodic regulation in a wild-derived mouse strain
Journal of Experimental Biology, vol. 223, no. 6, jeb217687Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.217687
- [ONLINE] View publication in Scopus
From gross morphology to gill transcriptome in farmed Atlantic salmon (Salmo salar): Lessons from multi-site sampling
Fish & Shellfish Immunology, vol. 91, pp. 467Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1016/j.fsi.2019.04.278
- [ONLINE] View publication in Mendeley
Impact of sea lice (Caligus rogercresseyi) infection levels on skin transcriptome in Atlantic salmon (Salmo salar)
Fish & Shellfish Immunology, vol. 91, pp. 436-437Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1016/j.fsi.2019.04.196
- [ONLINE] View publication in Mendeley
Switching off the furnace: brown adipose tissue and lactation
Molecular Aspects of Medicine, vol. 68, pp. 18-41Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.mam.2019.06.003
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Limits to sustained energy intake XXVIII: Beneficial effects of high dietary fat on lactation performance in mice
Journal of Experimental Biology, vol. 221, jeb180828Contributions to Journals: ArticlesBrown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo
Molecular Metabolism, vol. 6, no. 10, pp. 1198-1211Contributions to Journals: ArticlesNutrigenomics and immune function in fish: new insights from omics technologies
Developmental and Comparative Immunology, vol. 75, pp. 86-89Contributions to Journals: ArticlesTranscriptomic responses in the fish intestine
Developmental and Comparative Immunology, vol. 64, pp. 103-117Contributions to Journals: ArticlesGut health and integrity in atlantic salmon fed plant protein diets
Fish & Shellfish Immunology, vol. 53, pp. 69Contributions to Journals: AbstractsLimits to sustained energy intake. XXIII. Does heat dissipation capacity limit the energy budget of lactating bank voles?
Journal of Experimental Biology, vol. 219, no. 6, pp. 805-815Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.134437
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/8337/1/805.full.pdf
Differential responses of the gut transcriptome to plant protein diets in farmed Atlantic salmon
BMC Genomics, vol. 17, pp. 1-16Contributions to Journals: ArticlesAtlantic salmon (Salmo salar) parr as a model to predict the optimum inclusion of air classified faba bean protein concentrate in feeds for seawater salmon
Aquaculture, vol. 444, pp. 70-78Contributions to Journals: ArticlesFunctional Divergence of Type 2 Deiodinase Paralogs in the Atlantic Salmon
Current Biology, vol. 25, no. 7, pp. 936-941Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.cub.2015.01.074
Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice
Metabolism, vol. 64, no. 2, pp. 305-314Contributions to Journals: ArticlesLimits to sustained energy intake. XXII. Reproductive performance of two selected mouse lines with different thermal conductance
Journal of Experimental Biology, vol. 217, no. 20, pp. 3718-3732Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.103705
Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21
Aging Cell, vol. 13, no. 5, pp. 817-827Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/acel.12238
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/3721/1/acel12238.pdf
Limits to sustained energy intake. XXI. Effect of exposing the mother, but not her pups, to a cold environment during lactation in mice
Journal of Experimental Biology, vol. 216, no. 23, pp. 4326-4333Contributions to Journals: ArticlesLimits to sustained energy intake. XVI. Body temperature and physical activity of female mice during pregnancy
Journal of Experimental Biology, vol. 216, no. 12, pp. 2328-2338Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.078410
Limits to sustained energy intake. XV. Effects of wheel running on the energy budget during lactation
Journal of Experimental Biology, vol. 216, no. 12, pp. 2316-2327Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.078402
Limits to sustained energy intake. XVII. Lactation performance in MF1 mice is not programmed by fetal number during pregnancy
Journal of Experimental Biology, vol. 216, no. 12, pp. 2339-2348Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.078428
Strong pituitary and hypothalamic responses to photoperiod but not to 6-methoxy-2-benzoxazolinone in female common voles (Microtus arvalis)
General and Comparative Endocrinology, vol. 179, no. 2, pp. 289-295Contributions to Journals: ArticlesSeasonal leptin resistance is associated with impaired signalling via JAK2-STAT3 but not ERK, possibly mediated by reduced hypothalamic GRB2 protein
Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology, vol. 182, no. 4, pp. 553-567Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s00360-011-0637-4
Negative correlation between milk production and brown adipose tissue gene expression in lactating mice
Journal of Experimental Biology, vol. 214, no. 24, pp. 4160-4170Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.061382
- [ONLINE] View publication in Scopus
Limits to sustained energy intake. XIII. Recent progress and future perspectives
Journal of Experimental Biology, vol. 214, no. 2, pp. 230-241Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.048603
- [ONLINE] View publication in Scopus
The heat dissipation limit theory and evolution of life histories in endotherms-time to dispose of the disposable soma theory?
Integrative and Comparative Biology, vol. 50, no. 5, pp. 793-807Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/icb/icq049
- [ONLINE] View publication in Scopus
Shaved mice have improved performance during lactation
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, vol. 153, no. 2, pp. S149Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.cbpa.2009.04.289
The contribution of animal models to the study of obesity
Laboratory Animals, vol. 42, no. 4, pp. 413-432Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1258/la.2007.006067
Limits to sustained energy intake. X.: Effects of fur removal on reproductive performance in laboratory mice
Journal of Experimental Biology, vol. 210, pp. 4233-4243Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.009779
Animal models of obesity
Obesity Reviews, vol. 8, no. Suppl 1, pp. 55-61Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1467-789X.2007.00319.x
Regulation of body mass and adiposity in the field vole, Microtus agrestis: a model of leptin resistance
Journal of Endocrinology, vol. 192, no. 2, pp. 271-278Contributions to Journals: Literature Reviews- [ONLINE] DOI: https://doi.org/10.1677/JOE-06-0074
Limits to sustained energy intake IX: a review of hypotheses
Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology, vol. 175, pp. 375-394Contributions to Journals: Literature Reviews- [ONLINE] DOI: https://doi.org/10.1007/s00360-005-0013-3
Photoperiodic effects on body mass, energy balance and hypothalamic gene expression in the bank vole
Journal of Experimental Biology, vol. 207, pp. 165-177Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.00719
The functional significance of individual variation in basal metabolic rate
Physiological and Biochemical Zoology, vol. 77, pp. 900-915Contributions to Journals: ArticlesLimits to sustained energy intake VI. Energetics of lactation in laboratory mice at thermoneutrality
Journal of Experimental Biology, vol. 206, no. 23, pp. 4255-4266Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.00674
Limits to sustained energy intake VII: Milk energy output in laboratory mice at thermoneutralith
Journal of Experimental Biology, vol. 206, no. 23, pp. 4267-4281Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.00675
Limits to sustained energy intake VIII: Resting metabolic rate and organ morphology of laboratory mice lactating at thermoneutralith
Journal of Experimental Biology, vol. 206, no. 23, pp. 4283-4291Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1242/jeb.00676
Energetics of lactation in laboratory mice at thermoneutrality
The FASEB Journal, vol. 15, no. 4Contributions to Journals: ArticlesLimits to sustained energy intake during lactation in the mouse Mus musculus
The FASEB Journal, vol. 15, no. 4Contributions to Journals: ArticlesEffects of altitude and temperature on organ phenotypic plasticity along an altitudinal gradient
Journal of Experimental Biology, vol. 204, pp. 1991-2000Contributions to Journals: ArticlesLiving fast and dying old.
The FASEB Journal, vol. 14, no. 4, pp. A757Contributions to Journals: ArticlesPreparation of hydrogen from water by reduction with lithium aluminium hydride for the analysis of delta H-2 by isotope ratio mass spectrometry
Rapid Communications in Mass Spectrometry, vol. 14, pp. 450-453Contributions to Journals: ArticlesIsotope dilution spaces of mice injected simultaneously with deuterium, tritium and oxygen-18
Journal of Experimental Biology, vol. 202, pp. 2839-2849Contributions to Journals: Articles