Research Technician
- About
-
- Email Address
- gary.duncan@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438669
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Gary has over 25 years of Mass Spectrometry experience. He started work at what was then the Rowett Research Institute in 1986, and after six weeks training in analytical techniques, started working in the Gas Isotope Ratio Mass Spectrometry (GIRMS) laboratory assisting Dr Brian McGaw and Mr Eric Milne. As interest in this technique grew, the lab eventually had four mass spectrometers dedicated to analysing the stable isotopes of Carbon, Hydrogen and Oxygen from a variety of biological sources, supporting research into energy expenditure and protein synthesis. The research programmes of the Rowett then required Liquid Chromatography Mass Spectrometry (LC/MS) and a MAT 900 double-sector LC-MS/MS system was purchased in 1998, along with a LaserMAT MALDI mass spectrometer. Initially his role was to develop techniques for sample analysis on the MALDI, but soon took over the role of managing the LC/MS mass facility. This coincided with a ‘take-off’ in the popularity of using LCMSMS in sample analysis, firstly in the growth of identifying proteins separated on 2D gels and more recently the targeted quantitation analysis of small molecules. The main areas of analysis are in the quantification of Polyphenols relating to dietary consumption and human health and the quantification of Mycotoxins in foods and crops, in particular, the detoxification of Deoxynivalenol. The LCMSMS facility now has four mass spectrometers, with access to an ion trap to support work in these areas of research.
Other Areas of interest include:
- Vitamin D3
- Methylamines
- Anthocyanins
- Nicotinamides
- Carboxymethyl Lysines
- Antibiotics
Latest Publications
Buckwheat (Fagopyrum esculentum) Hulls Are a Rich Source of Fermentable Dietary Fibre and Bioactive Phytochemicals: International Journal of Molecular Sciences
International Journal of Molecular Sciences, vol. 24, no. 22, 16310Contributions to Journals: ArticlesHabitual consumption of high-fibre bread fortified with bean hulls increased plasma indole-3-propionic concentration and decreased putrescine and deoxycholic acid faecal concentrations in healthy volunteers
British Journal of Nutrition, vol. 130, no. 9, pp. 1521-1536Contributions to Journals: ArticlesBioprocessing of Hempseed (Cannabis sativa L.) Food By-Products Increased Nutrient and Phytochemical In Vitro Bioavailability during Digestion and Microbial Fermentation
Applied Sciences, vol. 13, no. 9, 5781Contributions to Journals: ArticlesFree and Modified Mycotoxins in Organic and Conventional Oats (Avena sativa L.) Grown in Scotland
Toxins, vol. 15, no. 4, 247Contributions to Journals: ArticlesBuckwheat, Fava Bean and Hemp Flours Fortified with Anthocyanins and Other Bioactive Phytochemicals as Sustainable Ingredients for Functional Food Development
Nutraceuticals, vol. 2, no. 3, pp. 150-161Contributions to Journals: Articles
- Publications
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Page 6 of 6 Results 51 to 59 of 59
Biochemical and proteomic changes in the colon and liver of rats in response to long-term folate deficiency
Proceedings of the Nutrition Society, vol. 66, no. Suppl. OCA-B, pp. 111AContributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1017/S0029665107005952
Extra Virgin Olive Oils Increase Hepatic Fat Accumulation and Hepatic Antioxidant Protein Levels in APOE-/- Mice
Journal of Proteome Research, vol. 6, no. 10, pp. 4041-4054Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1021/pr070321a
Salicylate modulates oxidative stress in the rat colon: a proteomic approach
Biochemical Pharmacology, vol. 72, no. 2, pp. 204-216Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.bcp.2006.04.012
A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria
Microbiology , vol. 152, no. 1, pp. 179-185Contributions to Journals: ArticlesDivergent mechanisms of cis9, trans11-and trans10, cis12-conjugated linoleic acid affecting insulin resistance and inflammation in apolipoprotein E knockout mice: a proteomics approach
The FASEB Journal, vol. 19, no. 9, pp. 1746-1767Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1096/fj.05-3953fje
A proteomics approach to identify changes in protein profiles in pre-cancerous colon
Biochemical and Biophysical Research Communications, vol. 330, no. 1, pp. 81-87Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.bbrc.2005.02.125
Rat metallothionein-2 contains N-alpha-acetylated and unacetylated isoforms
Electrophoresis, vol. 20, no. 7, pp. 1613-1618Contributions to Journals: ArticlesThe Influence of Exercise on the Energy Requirements of Adult Males in the UK
British Journal of Nutrition, vol. 72, no. 6, pp. 799-813Contributions to Journals: ArticlesA Rapid Method for the Preparation of Combustion Samples for Stable Carbon Isotope Analysis by Isotope Ratio Mass-Spectrometry
Biomedical & Environmental Mass Spectrometry, vol. 16, no. 1-12, pp. 269-273Contributions to Journals: Articles