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Dr Renato Coelho Dos Santos

Dr Renato Coelho Dos Santos
Dr Renato Coelho Dos Santos
Dr Renato Coelho Dos Santos

Advanced Research Fellow

About
Email Address
renato.santos@abdn.ac.uk
Telephone Number
+44 (0)1224 438577
Office Address

Liberty Building, Room GD07

Foresterhill Road

AB25 2ZP

School/Department
School of Medicine, Medical Sciences and Nutrition
ORCiD
Scopus
Google Scholar
Pure

Biography

I obtained the BSc in Biology in 2008, and the Doctorate degree (Cell Biology) in 2014 from the Faculty of Sciences and Technology, University of Coimbra, Portugal. My work was focused on numerous aspects of cellular and, particularly, mitochondrial biology, namely, mitochondrial biogenesis, mitochondrial fission and fusion and also autophagy/mitophagy. The main subject of my work was to understand the relation between diabetes and the propensity do develop dementia, particularly Alzheimer's disease. In 2017, I joined the team of Dr. Charles Harrington at the Institute of Medical Sciences, University of Aberdeen. My research interests include the understanding of neuropathological processes, uncovering of therapeutic targets and study of efficient therapeutic approaches to tackle progression of neurodegenerative diseases.  

Qualifications

  • BSc Biology 
    2008 - University of Coimbra, Portugal 
  • PhD Cell Biology 
    2014 - University of Coimbra, Portugal 

Internal Memberships

03/2023-02/2025: Board Member - School Ethics Review Board (SERB), for the School of Medicine, Medical Sciences and Nutrition

Latest Publications

View My Publications

Research

Research Overview

Neurodegeneration

Alzheimer's disease

Tau protein

Mitochondria

Oxidative Stress

Autophagy/Mitophagy

Therapeutics

Publications

Page 3 of 6 Results 21 to 30 of 56

  • Defective HIF signaling pathway and brain response to hypoxia in neurodegenerative diseases: not an "iffy" question!

    Correia, S. C., Carvalho, C., Cardoso, S., Santos, R. X., Plácido, A. I., Candeias, E., Duarte, A. I., Moreira, P. I.
    Current Pharmaceutical Design, vol. 19, no. 38, pp. 6809-6822
    Contributions to Journals: Articles

  • Effects of type 1 diabetes and insulin therapy on brain mitochondrial dynamics and autophagy

    Coelho Dos Santos, R. X., Correia, S. C., Santos, M. S., da Silva Moreira, P. I.
    XIII Meeting of the Portuguese Society for Neuroscience
    Contributions to Conferences: Posters

  • Tolerância cerebral mediada pelo pré-condicionamento por hipoxia num modelo animal de insulinorresistência central

    Correia, S. C., Santos, R. X., Casadesus, G., Lamanna, J. C., Perry, G., Smith, M. A., da Silva Moreira, P. I.
    Annual Meeting of the Portuguese Society of Diabetology
    Contributions to Conferences: Posters

  • The impairment of insulin signaling in Alzheimer's disease

    Candeias, E., Duarte, A. I., Carvalho, C., Correia, S. C., Cardoso, S., Santos, R. X., Plácido, A. I., Perry, G., Moreira, P. I.
    IUBMB life, vol. 64, no. 12, pp. 951-957
    Contributions to Journals: Review articles

  • Alzheimer disease as a vascular disorder: where do mitochondria fit?

    Correia, S. C., Santos, R. X., Cardoso, S., Carvalho, C., Candeias, E., Duarte, A. I., Plácido, A. I., Santos, M. S., Moreira, P. I.
    Experimental Gerontology, vol. 47, no. 11, pp. 878-886
    Contributions to Journals: Review articles

  • Diabetes disturbs autophagy and mitochondrial dynamics in the brain

    Coelho Dos Santos, R. X., Santos, M. S., Seiça, R., Oliveira, C. R., da Silva Moreira, P. I.
    26th Meeting of the Portuguese group for the study of brain aging and dementia
    Contributions to Conferences: Posters

  • Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities

    Carvalho, C., Cardoso, S., Correia, S. C., Santos, R. X., Santos, M. S., Baldeiras, I., Oliveira, C. R., Moreira, P. I.
    Diabetes, vol. 61, no. 5, pp. 1234-1242
    Contributions to Journals: Articles

  • Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation

    Correia, S. C., Santos, R. X., Carvalho, C., Cardoso, S., Candeias, E., Santos, M. S., Oliveira, C. R., Moreira, P. I.
    Brain Research, vol. 1441, pp. 64-78
    Contributions to Journals: Review articles

  • Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α

    Correia, S. C., Santos, R. X., Cardoso, S. M., Santos, M. S., Oliveira, C. R., Moreira, P. I.
    Neurobiology of Disease, vol. 45, no. 1, pp. 206-218
    Contributions to Journals: Articles

  • Diabetes unbalances autophagy and mitochondrial dynamics in the brain

    Coelho Dos Santos, R. X., Correia, S. C., Santos, M. S., Seiça, R., Oliveira, C. R., da Silva Moreira, P. I.
    12th FENS Forum
    Contributions to Conferences: Posters
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