Dr Renato Coelho Dos Santos

Dr Renato Coelho Dos Santos
Dr Renato Coelho Dos Santos
Dr Renato Coelho Dos Santos

Advanced Research Fellow

About
Email Address
renato.santos@abdn.ac.uk
Telephone Number
+44 (0)1224 438577
Office Address

Liberty Building, Room GD07

Foresterhill Road

AB25 2ZP

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I obtained the BSc in Biology in 2008, and the Doctorate degree (Cell Biology) in 2014 from the Faculty of Sciences and Technology, University of Coimbra, Portugal. My work was focused on numerous aspects of cellular and, particularly, mitochondrial biology, namely, mitochondrial biogenesis, mitochondrial fission and fusion and also autophagy/mitophagy. The main subject of my work was to understand the relation between diabetes and the propensity do develop dementia, particularly Alzheimer's disease. In 2017, I joined the team of Dr. Charles Harrington at the Institute of Medical Sciences, University of Aberdeen. My research interests include the understanding of neuropathological processes, uncovering of therapeutic targets and study of efficient therapeutic approaches to tackle progression of neurodegenerative diseases.  

Qualifications

  • BSc Biology 
    2008 - University of Coimbra, Portugal 
  • PhD Cell Biology 
    2014 - University of Coimbra, Portugal 

Internal Memberships

03/2023-02/2025: Board Member - School Ethics Review Board (SERB), for the School of Medicine, Medical Sciences and Nutrition

Latest Publications

View My Publications

Research

Research Overview

Neurodegeneration

Alzheimer's disease

Tau protein

Mitochondria

Oxidative Stress

Autophagy/Mitophagy

Therapeutics

Publications

Page 2 of 6 Results 11 to 20 of 56

  • Insulin therapy modulates mitochondrial dynamics and biogenesis, autophagy and tau protein phosphorylation in the brain of type 1 diabetic rats.

    Santos, R., Correia, S. C., Alves, M., Oliveira, P., Cardoso, S., Carvalho, C., Duarte, A., Santos, M., Moreira, P.
    Biochimica et Biophysica Acta, vol. 1842, no. 7, pp. 1154-1166
    Contributions to Journals: Articles
  • Role of Mitochondria and Oxidative stress in Parkinson's disease

    Coelho Dos Santos, R. X., Correia, S. C., Cardoso, S., Carvalho, C., Candeias, E., Plácido, A. I., Duarte, A. I., Santos, M. S., da Silva Moreira, P. I.
    Role of Oxidative Stress in Chronic Diseases. Dichi, I., Breganó, J. W., Colado Simão, A. N., Cecchini, R. (eds.). CRC Press, pp. 521-548, 28 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters (Peer-Reviewed)
  • The Janus Face of Insulin in Brain

    Duarte, A. I., Candeias, E., Correia, S. C., Santos, R. X., Carvalho, C., Cardoso, S., Plácido, A. I., Santos, M. S., Oliveira, C. R., da Silva Moreira, P. I.
    Metabolic Syndrome and Neurological Disorders. Farooqui, T., Farooqui, A. A. (eds.). John Wiley & Sons Ltd., pp. 85-113, 29 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters
  • Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease

    Santos, R. X., Correia, S. C., Zhu, X., Smith, M. A., Moreira, P. I., Castellani, R. J., Nunomura, A., Perry, G.
    Antioxidants & Redox Signaling, vol. 18, no. 18, pp. 2444–2457
    Contributions to Journals: Articles
  • Type 2 diabetic and Alzheimer's disease mice present similar behavioral, cognitive, and vascular anomalies.

    Carvalho, C., Machado, N., Mota, P. C., Correia, S. C., Cardoso, S., Santos, R. X., Santos, M. S., Oliveira, C. R., Moreira, P. I.
    Journal of Alzheimer's Disease, vol. 35, no. 3, pp. 623-635
    Contributions to Journals: Articles
  • Hyperglycemia, hypoglycemia and dementia: role of mitochondria and uncoupling proteins

    Cardoso, S., Correia, S., Santos, R., Carvalho, C., Candeias, E., Duarte, A., Plácido, A., Santos, M., Moreira, P.
    Current molecular medicine, vol. 13, no. 4, pp. 586-601
    Contributions to Journals: Articles
  • Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease.

    Correia, S. C., Santos, R. X., Santos, M. S., Casadesus, G., LaManna, J. C., Perry, G., Smith, M. A., Moreira, P. I.
    Current Alzheimer Research, vol. 10, no. 4, pp. 406-419
    Contributions to Journals: Articles
  • Crosstalk between diabetes and brain: glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration

    Duarte, A. I., Candeias, E., Correia, S. C., Santos, R. X., Carvalho, C., Cardoso, S., Plácido, A., Santos, M. S., Oliveira, C. R., Moreira, P. I.
    Biochimica et Biophysica Acta, vol. 1832, no. 4, pp. 527-541
    Contributions to Journals: Articles
  • Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance

    Cardoso, S., Santos, R. X., Correia, S. C., Carvalho, C., Santos, M. S., Baldeiras, I., Oliveira, C. R., Moreira, P. I.
    Neurobiology of Disease, vol. 49, pp. 1-12
    Contributions to Journals: Articles
  • A insulina diminui os níveis de proteína tau fosforilada e modula a dinâmica mitocondrial no cérebro de ratos diabéticos tipo 1

    Coelho Dos Santos, R. X., Correia, S. C., Santos, M. S., da Silva Moreira, P. I.
    Annual Meeting of the Portuguese Society of Diabetology
    Contributions to Conferences: Posters
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