Professor David St Clair

Professor David St Clair

Chair in Applied Medicine

Overview

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Research

Research Overview

Psychiatric Genetics, particularly of schizophrenia.

Publications

Publications 

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Page 1 of 4 Results 1 to 50 of 190

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pavlides, J. M., Trzaskowski, M., Byrne, E. M., Pers, T. H., Holmans, P. A., Richards, A. L., Abbott, L., Agerbo, E., Akil, H., Albani, D., Alliey-Rodriguez, N., Als, T. D., Anjorin, A., Antilla, V., Awasthi, S., Badner, J. A., Bækvad-Hansen, M., Barchas, J. D., Bass, N., Bauer, M., Belliveau, R., Bergen, S. E., Pedersen, C. B., Bøen, E., Boks, M. P., Boocock, J., Budde, M., Bunney, W., Burmeister, M., Bybjerg-Grauholm, J., Byerley, W., Casas, M., Cerrato, F., Cervantes, P., Chambert, K., Charney, A. W., Chen, D., St Clair, D., eQTLGen Consortium, BIOS Consortium, the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium

    Nature Genetics, vol. 51, pp. 793-803

    Contributions to Journals: Articles

  • Consensus paper of the WFSBP Task Force on Genetics: Genetics, epigenetics and gene expression markers of major depressive disorder and antidepressant response

    Fabbri, C., Hosak, L., Mössner, R., Giegling, I., Mandelli, L., Bellivier, F., Claes, S., Collier, D. A., Corrales, A., Delisi, L. E., Gallo, C., Gill, M., Kennedy, J. L., Leboyer, M., Lisoway, A., Maier, W., Marquez, M., Massat, I., Mors, O., Muglia, P., Nöthen, M. M., O’Donovan, M. C., Ospina-Duque, J., Propping, P., Shi, Y., St Clair, D., Thibaut, F., Cichon, S., Mendlewicz, J., Rujescu, D., Serretti, A.

    World Journal of Biological Psychiatry, vol. 18, no. 1, pp. 5-28

    Contributions to Journals: Review articles

  • Genetics of schizophrenia: A consensus paper of the WFSBP Task Force on Genetics

    Giegling, I., Hosak, L., Mössner, R., Serretti, A., Bellivier, F., Claes, S., Collier, D. A., Corrales, A., DeLisi, L. E., Gallo, C., Gill, M., Kennedy, J. L., Leboyer, M., Maier, W., Marquez, M., Massat, I., Mors, O., Muglia, P., Nöthen, M. M., Ospina-Duque, J., Owen, M. J., Propping, P., Shi, Y. Y., St Clair, D., Thibaut, F., Cichon, S., Mendlewicz, J., O'Donovan, M. C., Rujescu, D.

    World Journal of Biological Psychiatry, vol. 18, no. 7, pp. 492-505

    Contributions to Journals: Articles

  • An integrated genetic-epigenetic analysis of schizophrenia: Evidence for co-localization of genetic associations and differential DNA methylation

    Hannon, E., Dempster, E., Viana, J., Burrage, J., Smith, A. R., Macdonald, R., St Clair, D., Mustard, C., Breen, G., Therman, S., Kaprio, J., Toulopoulou, T., Pol, H. E., Bohlken, M. M., Kahn, R. S., Nenadic, I., Hultman, C. M., Murray, R. M., Collier, D. A., Bass, N., Gurling, H., McQuillin, A., Schalkwyk, L., Mill, J.

    Genome Biology, vol. 17, 176

    Contributions to Journals: Articles

  • Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function

    Thomson, P. A., Duff, B., Blackwood, D. H., Romaniuk, L., Watson, A., Whalley, H. C., Li, X., Dauvermann, M. R., Moorhead, T. W. J., Bois, C., Ryan, N. M., Redpath, H., Hall, L., Morris, S. W., Van Beek, E. J., Roberts, N., Porteous, D. J., St Clair, D., Whitcher, B., Dunlop, J., Brandon, N. J., Hughes, Z. A., Hall, J., McIntosh, A., Lawrie, S. M.

    npj Schizophrenia, vol. 2, 16024

    Contributions to Journals: Articles

  • Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

    Singh, T., Kurki, M. I., Curtis, D., Purcell, S. M., Crooks, L., McRae, J., Suvisaari, J., Chheda, H., Blackwood, D., Breen, G., Pietilinen, O., Gerety, S. S., Ayub, M., Blyth, M., Cole, T., Collier, D., Coomber, E. L., Craddock, N., Daly, M. J., Danesh, J., DiForti, M., Foster, A., Freimer, N. B., Geschwind, D., Johnstone, M., Joss, S., Kirov, G., Körkkö, J., Kuismin, O., Holmans, P., Hultman, C. M., Iyegbe, C., Lönnqvist, J., Mnnikkö, M., McCarroll, S. A., McGuffin, P., McIntosh, A. M., McQuillin, A., Moilanen, J. S., Moore, C., Murray, R. M., Newbury-Ecob, R., Ouwehand, W., Paunio, T., Prigmore, E., Rees, E., Roberts, D., Sambrook, J., Sklar, P., St Clair, D., Veijola, J., Walters, J. T., Williams, H., Sullivan, P. F., Hurles, M. E., O'Donovan, M. C., Palotie, A., Owen, M. J., Barrett, J. C.

    Nature Neuroscience, vol. 19, no. 4, pp. 571-577

    Contributions to Journals: Articles

  • Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

    Franke, B., Stein, J. L., Ripke, S., Anttila, V., Hibar, D. P., van Hulzen, K. J. E., Arias-Vasquez, A., Smoller, J. W., Nichols, T. E., Neale, M. C., McIntosh, A. M., Lee, P., McMahon, F. J., Meyer-Lindenberg, A., Mattheisen, M., Andreassen, O. A., Gruber, O., Sachdev, P. S., Roiz-Santianez, R., Saykin, A. J., Ehrlich, S., Mather, K. A., Turner, J. A., Wright, M. J., O'Donovan, M. C., Thompson, P. M., Neale, B. M., Medland, S. E., Sullivan, P. F., Psychiat Genomics Consortium, ENIGMA Consortium, St Clair, D. M., Pike, G. B.

    Nature Neuroscience, vol. 19, no. 3, pp. 420-431

    Contributions to Journals: Articles

  • Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case-control sample of schizophrenia

    Ingason, A., Giegling, I., Hartmann, A. M., Genius, J., Konte, B., Friedl, M., Ripke, S., Sullivan, P. F., St Clair, D., Collier, D. A., O'Donovan, M. C., Mirnics, K., Rujescu, D.

    Translational Psychiatry, vol. 5, e656

    Contributions to Journals: Articles

  • Bridging the translational divide: Identical cognitive touchscreen testing in mice and humans carrying mutations in a disease-relevant homologous gene

    Nithianantharajah, J., McKechanie, A. G., Stewart, T. J., Johnstone, M., Blackwood, D. H., St Clair, D., Grant, S. G., Bussey, T. J., Saksida, L. M.

    Scientific Reports, vol. 5, 14613

    Contributions to Journals: Articles

  • The UK10K project identifies rare variants in health and disease

    Walter, K., Min, J. L., Huang, J., Crooks, L., Memari, Y., McCarthy, S., Perry, J. R., Xu, C., Futema, M., Lawson, D., Iotchkova, V., Schiffels, S., Hendricks, A. E., Danecek, P., Li, R., Floyd, J., Wain, L. V., Barroso, I., Humphries, S. E., Hurles, M. E., Zeggini, E., Barrett, J. C., Plagnol, V., Richards, J. B., Greenwood, C. M., Timpson, N. J., Durbin, R., Bala, S., Clapham, P., Coates, G., Cox, T., Daly, A., Du, Y., Edkins, S., Ellis, P., Flicek, P., Guo, X., Guo, X., Huang, L., Jackson, D. K., Joyce, C., Keane, T., Kolb-Kokocinski, A., Langford, C., Li, Y., Liang, J., Lin, H., Liu, R., Breen, G., St Clair, D., UK10K Consortium

    Nature, vol. 526, no. 7571, pp. 82-89

    Contributions to Journals: Articles

  • Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness

    Johnstone, M., Maclean, A., Heyrman, L., Lenaerts, A., Nordin, A., Nilsson, L., De Rijk, P., Goossens, D., Adolfsson, R., St Clair, D. M., Hall, J., Lawrie, S. M., McIntosh, A. M., Del-Favero, J., Blackwood, D. H. R., Pickard, B. S.

    Journal of Neuropsychiatry and Clinical Neurosciences, vol. 1, no. 3, pp. 175-190

    Contributions to Journals: Articles

  • Prenatal Nutritional Deficiency Reprogrammed Postnatal Gene Expression in Mammal Brains: Implications for Schizophrenia

    Xu, J., He, G., Zhu, J., Zhou, X., Clair, D. S., Wang, T., Xiang, Y., Zhao, Q., Xing, Q., Liu, Y., Wang, L., Li, Q., He, L., Zhao, X.

    International Journal of Neuropsychopharmacology, vol. 18, no. 4, pyu054

    Contributions to Journals: Articles

  • No Association Between NRG1 and ErbB4 Genes and Psychopathological Symptoms of Schizophrenia

    Tosato, S., Zanoni, M., Bonetto, C., Tozzi, F., Francks, C., Ira, E., Tomassi, S., Bertani, M., Rujescu, D., Giegling, I., St Clair, D., Tansella, M., Ruggeri, M., Muglia, P.

    NeuroMolecular Medicine, vol. 16, no. 4, pp. 742-751

    Contributions to Journals: Articles

  • Common genetic variants on 1p13.2 associate with risk of autism

    Xia, K., Guo, H., Xun, G., Zuo, L., Peng, Y., He, Y., Xiong, Z., Sun, L., Pan, Q., Long, Z., Zou, X., Lu, L., Liu, Y., Tian, D., Long, L., Liu, Y., Peng, H., Luo, X., Su, W., Liang, D., Dai, H., Yan, X., Feng, Y., Tang, B., Miedzybrodzka, Z., Xia, J., Zhang, Z., Luo, X., Zhang, X., St Clair, D., Zhao, J., Zhang, F.

    Molecular Psychiatry, vol. 19, no. 11, pp. 1212-1219

    Contributions to Journals: Articles

  • Biological insights from 108 schizophrenia-associated genetic loci

    Ripke, S., Neale, B. M., Corvin, A., Walters, J. T., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C., Chen, R. Y., Chen, E. Y., Cheng, W., Cheung, E. F., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., St Clair, D., Schizophrenia Working Group of the Psychiatric Genomics Consortium

    Nature, vol. 511, no. 7510, pp. 421-427

    Contributions to Journals: Articles

  • Modeling a genetic risk for schizophrenia in iPSCs and Mice reveals neural stem cell deficits associated with adherens junctions and polarity

    Yoon, K. J., Nguyen, H. N., Ursini, G., Zhang, F., Kim, N. S., Wen, Z., Makri, G., Nauen, D., Shin, J. H., Park, Y., Chung, R., Pekle, E., Zhang, C., Towe, M., Hussaini, S. M. Q., Lee, Y., Rujescu, D., St. Clair, D., Kleinman, J. E., Hyde, T. M., Krauss, G., Christian, K. M., Rapoport, J. L., Weinberger, D. R., Song, H., Ming, G. L.

    Cell Stem Cell, vol. 15, no. 1, pp. 79-91

    Contributions to Journals: Articles

  • An inherited duplication at the gene p21 protein-activated Kinase 7 (PAK7) is a risk factor for psychosis

    Morris, D. W., Pearson, R. D., Cormican, P., Kenny, E. M., O'Dushlaine, C. T., Perreault, L. P. L., Giannoulatou, E., Tropea, D., Maher, B. S., Wormley, B., Kelleher, E., Fahey, C., Molinos, I., Bellini, S., Pirinen, M., Strange, A., Freeman, C., Thiselton, D. L., Elves, R. L., Regan, R., Ennis, S., Dinan, T. G., McDonald, C., Murphy, K. C., O'Callaghan, E., Waddington, J. L., Walsh, D., O'Donovan, M., Grozeva, D., Craddock, N., Stone, J., Scolnick, E., Purcell, S., Sklar, P., Coe, B., Eichler, E. E., Ophoff, R., Buizer, J., Szatkiewicz, J., Hultman, C., Sullivan, P., Gurling, H., Mcquillin, A., St Clair, D., Rees, E., Kirov, G., Walters, J., Blackwood, D., Johnstone, M., Donohoe, G., The International Schizophrenia Consortium (ISC), SGENE+ Consortium, O'Neill, F. A., The Wellcome Trust Case Control Consortium 2 (WTCCC2), Kendler, K. S., Gill, M., Riley, B. P., Spencer, C. C. A., Corvin, A.

    Human Molecular Genetics, vol. 23, no. 12, pp. 3316-3326

    Contributions to Journals: Articles

  • Recurrent deletions of ULK4 in schizophrenia: a gene crucial for neuritogenesis and neuronal motility

    Lang, B., Pu, J., Hunter, I., Liu, M., Martin-Granados, C., Reilly, T. J., Gao, G., Guan, Z., Li, W., Shi, Y., He, G., He, L., Stefansson, H., St Clair, D., Blackwood, D. H., McCaig, C. D., Shen, S.

    Journal of Cell Science, vol. 127, no. 3, pp. 630-640

    Contributions to Journals: Articles

  • A survey of rare coding variants in candidate genes in schizophrenia by deep sequencing

    Hu, X., Zhang, B., Liu, W., Paciga, S., He, W., Lanz, T. A., Kleiman, R., Dougherty, B., Hall, S. K., Mcintosh, A. M., Lawrie, S. M., Power, A., John, S. L., Blackwood, D., St Clair, D., Brandon, N. J.

    Molecular Psychiatry, vol. 19, no. 8, pp. 857-858

    Contributions to Journals: Letters

  • Can eye movements be used as a marker for major depression?

    Nouzova, E., Beedie, S. A., Bheemaraddi, S., Kuriakose, J., Kulkarni, M., Shand, A. J., Walker, N., St Clair, D., Benson, P. J.

    European Psychiatry, vol. 29, no. supplement 1, EPA-112

    Contributions to Journals: Abstracts

  • Mosaic copy number variation in schizophrenia

    Ruderfer, D. M., Chambert, K., Moran, J., Talkowski, M., Chen, E. S., Gigek, C., Gusella, J. F., Blackwood, D. H., Corvin, A., Gurling, H. M., Hultman, C. M., Kirov, G., Magnusson, P., O'Donovan, M. C., Owen, M. J., Pato, C., St Clair, D., Sullivan, P. F., Purcell, S. M., Sklar, P., Ernst, C.

    EJHG : European journal of human genetics : the official journal of the European Society of Human Genetics. , vol. 21, no. 9, pp. 1007-1011

    Contributions to Journals: Articles

  • A comprehensive family-based replication study of schizophrenia genes

    Aberg, K. A., Liu, Y., Bukszár, J., McClay, J. L., Khachane, A. N., Andreassen, O. A., Blackwood, D., Corvin, A., Djurovic, S., Gurling, H., Ophoff, R., Pato, C. N., Pato, M. T., Riley, B., Webb, T., Kendler, K., O'Donovan, M., Craddock, N., Kirov, G., Owen, M., Rujescu, D., St Clair, D., Werge, T., Hultman, C. M., Delisi, L. E., Sullivan, P., Van Den Oord, E. J.

    JAMA Psychiatry, vol. 70, no. 6, pp. 573-581

    Contributions to Journals: Articles

  • Rare CNVs and tag SNPs at 15q11.2 are associated with schizophrenia in the Han Chinese population

    Zhao, Q., Li, T., Zhao, X., Huang, K., Wang, T., Li, Z., Ji, J., Zeng, Z., Zhang, Z., Li, K., Feng, G., St Clair, D., He, L., Shi, Y.

    Schizophrenia Bulletin, vol. 39, no. 3, pp. 712-719

    Contributions to Journals: Articles

  • Novel Loci Associated with Increased Risk of Sudden Cardiac Death in the Context of Coronary Artery Disease

    Huertas-Vazquez, A., Nelson, C. P., Guo, X., Reinier, K., Uy-Evanado, A., Teodorescu, C., Ayala, J., Jerger, K., Chugh, H., Braund, P. S., Deloukas, P., Hall, A. S., Balmforth, A. J., Jones, M., Taylor, K. D., Pulit, S. L., Newton-Cheh, C., Gunson, K., Jui, J., Rotter, J. I., Albert, C. M., Samani, N. J., Chugh, S. S., Aerts, J., Ahmad, T., Arbury, H., Attwood, A., Auton, A., Ball, S. G., Balmforth, A. J., Barnes, C., Barrett, J. C., Barroso, I., Barton, A., Bennett, A. J., Bhaskar, S., Blaszczyk, K., Bowes, J., Brand, O. J., Braund, P. S., Bredin, F., Breen, G., Brown, M. J., Bruce, I. N., Bull, J., Burren, O. S., Burton, J., Hocking, L., Reid, D. M., St Clair, D., WTCCC+

    PloS ONE, vol. 8, no. 4, e59905

    Contributions to Journals: Articles

  • Simple viewing tests can detect eye movement abnormalities that distinguish schizophrenia cases from controls with exceptional accuracy

    Benson, P. J., Beedie, S. A., Shephard, E., Giegling, I., Rujescu, D., St Clair, D.

    Biological Psychiatry, vol. 72, no. 9, pp. 716-724

    Contributions to Journals: Articles

  • Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder

    Vassos, E., Steinberg, S., Cichon, S., Breen, G., Sigurdsson, E., Andreassen, O. A., Djurovic, S., Morken, G., Grigoroiu-Serbanescu, M., Diaconu, C. C., Czerski, P. M., Hauser, J., Babadjanova, G., Abramova, L. I., Mühleisen, T. W., Nöthen, M. M., Rietschel, M., McGuffin, P., Clair, D. S., Gustafsson, O., Melle, I., Pietiläinen, O. P. H., Ruggeri, M., Tosato, S., Werge, T., Ophoff, R. A., Rujescu, D., Børglum, A. D., Mors, O., Mortensen, P. B., Demontis, D., Hollegaard, M. V., van Winkel, R., Kenis, G., De Hert, M., Réthelyi, J. M., Bitter, I., Rubino, I. A., Golimbet, V., Kiemeney, L. A., van den Berg, L. H., Franke, B., Jönsson, E. G., Farmer, A., Stefansson, H., Stefansson, K., Collier, D. A., GROUP Consortium

    Biological Psychiatry, vol. 72, no. 8, pp. 645-650

    Contributions to Journals: Articles

  • Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: A polygenic risk score analysis

    Derks, E. M., Vorstman, J. A., Ripke, S., Kahn, R. S., Ophoff, R. A., O'Donovan, M. C., Craddock, N., Holmans, P. A., Hamshere, M., Williams, H. J., Moskvina, V., Dwyer, S., Georgieva, L., Zammit, S., Owen, M. J., Sullivan, P. F., Lin, D. Y., van den Oord, E., Kim, Y., Scott Stroup, T., Lieberman, J. A., St Clair, D., Kirov, G. K., Nikolov, I., Toncheva, D., Milanova, V., Morris, D. W., O'Dushlaine, C. T., Kenny, E., Quinn, E. M., Gill, M., Corvin, A., Blackwood, D. H., McGhee, K. A., Pickard, B., Malloy, P., Maclean, A. W., McIntosh, A., McQuillin, A., Choudhury, K., Datta, S., Pimm, J., Thirumalai, S., Puri, V., Krasucki, R., Lawrence, J., Quested, D., Bass, N., Gurling, H., Pato, M. T., The Schizophrenia Psychiatric Genomic Consortium

    PloS ONE, vol. 7, no. 6, e37852

    Contributions to Journals: Articles

  • Runs of homozygosity implicate autozygosity as a schizophrenia risk factor

    Keller, M. C., Simonson, M. A., Ripke, S., Neale, B. M., Gejman, P. V., Howrigan, D. P., Lee, S. H., Lencz, T., Levinson, D. F., Sullivan, P. F., Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium, St Clair, D. M.

    PLoS Genetics, vol. 8, no. 4, e1002656

    Contributions to Journals: Articles

  • Interplay between DISC1 and GABA signaling regulates neurogenesis in mice and risk for schizophrenia

    Kim, J. Y., Liu, C. Y., Zhang, F., Duan, X., Wen, Z., Song, J., Feighery, E., Lu, B., Rujescu, D., St Clair, D., Christian, K., Callicott, J. H., Weinberger, D. R., Song, H., Ming, G.

    Cell, vol. 148, no. 5, pp. 1051-1064

    Contributions to Journals: Articles

  • A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia

    Jia, P., Wang, L., Fanous, A. H., Chen, X., Kendler, K. S., Zhao, Z., Morris, D. W., O'Dushlaine, C. T., Kenny, E., Quinn, E. M., Gill, M., Corvin, A., O'Donovan, M. C., Kirov, G. K., Craddock, N. J., Holmans, P. A., Williams, N. M., Georgieva, L., Nikolov, I., Norton, N., Williams, H., Toncheva, D., Milanova, V., Owen, M. J., Hultman, C. M., Lichtenstein, P., Thelander, E. F., Sullivan, P., McQuillin, A., Choudhury, K., Datta, S., Pimm, J., Thirumalai, S., Puri, V., Krasucki, R., Lawrence, J., Quested, D., Bass, N., Gurling, H., Crombie, C., Fraser, G., Kuan, S. L., Walker, N., St Clair, D., Blackwood, D. H., Muir, W. J., McGhee, K. A., Pickard, B., Malloy, P., Maclean, A. W., The International Schizophrenia Consortium (ISC)

    Journal of Medical Genetics, vol. 49, no. 2, pp. 96-103

    Contributions to Journals: Articles

  • Association study of nonsynonymous single nucleotide polymorphisms in schizophrenia

    Carrera, N., Arrojo, M., Sanjuán, J., Ramos-Ríos, R., Paz, E., Suárez-Rama, J. J., Páramo, M., Agra, S., Brenlla, J., Martínez, S., Rivero, O., Collier, D. A., Palotie, A., Cichon, S., Nöthen, M. M., Rietschel, M., Rujescu, D., Stefansson, H., Steinberg, S., Sigurdsson, E., St Clair, D., Tosato, S., Werge, T., Stefansson, K., González, J. C., Valero, J., Gutiérrez-Zotes, A., Labad, A., Martorell, L., Vilella, E., Carracedo, ., Costas, J.

    Biological Psychiatry, vol. 71, no. 2, pp. 169-177

    Contributions to Journals: Articles

  • HDAC9 is implicated in schizophrenia and expressed specifically in post-mitotic neurons but not in adult neural stem cells

    Lang, B., Alrahbeni, T. M. A., St Clair, D., Blackwood, D. H., McCaig, C. D., Shen, S.

    American Journal of Stem Cells, vol. 1, no. 1, pp. 31-41

    Contributions to Journals: Articles

  • Common variants on 8p12 and 1q24.2 confer risk of schizophrenia

    Shi, Y., Li, Z., Xu, Q., Wang, T., Li, T., Shen, J., Zhang, F., Chen, J., Zhou, G., Ji, W., Li, B., Xu, Y., Liu, D., Wang, P., Yang, P., Liu, B., Sun, W., Wan, C., Qin, S., He, G., Steinberg, S., Cichon, S., Werge, T., Sigurdsson, E., Tosato, S., Palotie, A., Nöthen, M. M., Rietschel, M., Ophoff, R. A., Collier, D. A., Rujescu, D., St Clair, D., Stefansson, H., Stefansson, K., Ji, J., Wang, Q., Li, W., Zheng, L., Zhang, H., Feng, G., He, L.

    Nature Genetics, vol. 43, pp. 1224-1227

    Contributions to Journals: Articles

  • GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia

    Chen, X., Lee, G., Maher, B. S., Fanous, A. H., Chen, J., Zhao, Z., Guo, A., Van Den Oord, E., Sullivan, P. F., Shi, J., Levinson, D. F., Gejman, P. V., Sanders, A., Duan, J., Owen, M. J., Craddock, N. J., O'Donovan, M. C., Blackman, J., Lewis, D., Kirov, G. K., Qin, W., Schwab, S., Wildenauer, D., Chowdari, K., Nimgaonkar, V., Straub, R. E., Weinberger, D. R., O'Neill, F. A., Walsh, D., Bronstein, M., Darvasi, A., Lencz, T., Malhotra, A. K., Rujescu, D., Giegling, I., Werge, T., Hansen, T., Ingason, A., Nöethen, M. M., Rietschel, M., Cichon, S., Djurovic, S., Andreassen, O. A., Cantor, R. M., Ophoff, R., Corvin, A., St Clair, D., Crombie, C., Fraser, G., Kuan, S. L., St Clair, D., Genetic Risk and Outcome in Psychosis (GROUP), The International Schizophrenia Consortium (ISC)

    Molecular Psychiatry, vol. 16, no. 11, pp. 1117-1129

    Contributions to Journals: Articles

  • Common variants at VRK2 and TCF4 conferring risk of schizophrenia

    Steinberg, S., de Jong, S., Andreassen, O. A., Werge, T., Børglum, A. D., Mors, O., Mortensen, P. B., Gustafsson, O., Costas, J., Pietiläinen, O. P. H., Demontis, D., Papiol, S., Huttenlocher, J., Mattheisen, M., Breuer, R., Vassos, E., Giegling, I., Fraser, G., Walker, N., Tuulio-Henriksson, A., Suvisaari, J., Lönnqvist, J., Paunio, T., Agartz, I., Melle, I., Djurovic, S., Strengman, E., Jürgens, G., Glenthøj, B., Terenius, L., Hougaard, D. M., Ørntoft, T., Wiuf, C., Didriksen, M., Hollegaard, M. V., Nordentoft, M., van Winkel, R., Kenis, G., Abramova, L., Kaleda, V., Arrojo, M., Sanjuán, J., Arango, C., Sperling, S., Rossner, M., Ribolsi, M., Magni, V., Siracusano, A., Christiansen, C., St Clair, D., Irish Schizophrenia Genomics Consortium

    Human Molecular Genetics, vol. 20, no. 20, pp. 4076-4081

    Contributions to Journals: Articles

  • Genome-wide association study identifies five new schizophrenia loci

    Ripke, S., Sanders, A. R., Kendler, K. S., Levinson, D. F., Sklar, P., Holmans, P. A., Lin, D., Duan, J., Ophoff, R. A., Andreassen, O. A., Scolnick, E., Cichon, S., St Clair, D., Corvin, A., Gurling, H., Werge, T., Rujescu, D., Blackwood, D. H. R., Pato, C. N., Malhotra, A. K., Purcell, S., Dudbridge, F., Neale, B. M., Rossin, L., Visscher, P. M., Posthuma, D., Ruderfer, D. M., Fanous, A., Stefansson, H., Steinberg, S., Mowry, B. J., Golimbet, V., De Hert, M., Jönsson, E. G., Bitter, I., Pietiläinen, O. P. H., Collier, D. A., Tosato, S., Agartz, I., Albus, M., Alexander, M., Amdur, R. L., Amin, F., Bass, N., Bergen, S. E., Black, D. W., Børglum, A. D., Brown, M. A., Bruggeman, R., Buccola, N. G., Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium

    Nature Genetics, vol. 43, no. 10, pp. 969-976

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  • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

    Sklar, P., Ripke, S., Scott, L. J., Andreassen, O. A., Cichon, S., Craddock, N., Edenberg, H. J., Nurnberger, J. I., Rietschel, M., Blackwood, D., Corvin, A., Flickinger, M., Guan, W., Mattingsdal, M., McQuillin, A., Kwan, P., Wienker, T. F., Daly, M., Dudbridge, F., Holmans, P. A., Lin, D., Burmeister, M., Greenwood, T. A., Hamshere, M. L., Muglia, P., Smith, E. N., Zandi, P. P., Nievergelt, C. M., McKinney, R., Shilling, P. D., Schork, N. J., Bloss, C. S., Foroud, T., Koller, D. L., Gershon, E. S., Liu, C., Badner, J. A., Scheftner, W. A., Lawson, W. B., Nwulia, E. A., Hipolito, M., Coryell, W., Rice, J., Byerley, W., McMahon, F. J., Schulze, T. G., Berrettini, W., Li, J., Breen, G., St Clair, D., Psychiatric GWAS Consortium Bipolar Disorder Working Group

    Nature Genetics, vol. 43, no. 10, pp. 977-983

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  • Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia

    Chen, J., Lee, G., Fanous, A. H., Zhao, Z., Jia, P., O'Neill, A., Walsh, D., Kendler, K. S., Chen, X., The International Schizophrenia Consortium (ISC), St Clair, D.

    Schizophrenia Research, vol. 131, no. 1-3, pp. 43-51

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  • At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia

    Hansen, T., Ingason, A., Djurovic, S., Melle, I., Fenger, M., Gustafsson, O., Jakobsen, K. D., Rasmussen, H. B., Tosato, S., Rietschel, M., Frank, J., Owen, M., Bonetto, C., Suvisaari, J., Thygesen, J. H., Pétursson, H., Lönnqvist, J., Sigurdsson, E., Giegling, I., Craddock, N., O'Donovan, M. C., Ruggeri, M., Cichon, S., Ophoff, R. A., Pietiläinen, O., Peltonen, L., Nöthen, M. M., Rujescu, D., St Clair, D., Collier, D. A., Andreassen, O. A., Werge, T.

    Biological Psychiatry, vol. 70, no. 1, pp. 59-63

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  • DISC1 exon 11 rare variants found more commonly in schizoaffective spectrum cases than controls

    Green, E. K., Grozeva, D., Sims, R., Raybould, R., Forty, L., Gordon-Smith, K., Russell, E., St. Clair, D., Young, A. H., Ferrier, I. N., Kirov, G., Jones, I., Jones, L., Owen, M. J., O'Donovan, M. C., Craddock, N.

    American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, vol. 156, no. 4, pp. 490-492

    Contributions to Journals: Articles

  • Evidence of sex-modulated association of ZNF804A with schizophrenia

    Zhang, F., Chen, Q., Ye, T., Lipska, B. K., Straub, R. E., Vakkalanka, R., Rujescu, D., St Clair, D., Hyde, T. M., Bigelow, L., Kleinman, J. E., Weinberger, D. R.

    Biological Psychiatry, vol. 69, no. 10, pp. 914-917

    Contributions to Journals: Articles

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