University of Aberdeen leads the fight against cancer with £1.5 million grant

University of Aberdeen leads the fight against cancer with £1.5 million grant

The University of Aberdeen has secured a grant of up to £1.5million from Cancer Research UK to study how tumours develop.

The grant will fund a five-year programme of research led by Professor Anne Donaldson and will create a series of new research posts in her laboratory at the Foresterhill health campus.

The funds will enable Professor Donaldson and her team to gain a greater understanding of how cells become cancerous and how treatment could be targeted more effectively.

She said: “Our research will focus on a cell component known as RIF1 that we know plays a pivotal role in cancer but whose function we do not yet fully understand. RIF1 is important for maintaining the DNA in chromosomes on which our genetic information is written.  We want to investigate what happens to chromosomes when RIF1 activity goes wrong and how this contributes to cancer.

Joint leader of the research team Dr Shin-ichiro Hiraga added: “Our laboratory here in Aberdeen has developed a reputation for quality research exploring fundamental mechanisms that go wrong in cancer, and we will use the grant to take this work forward.  It’s great that this award will allow us to extend our work into human cells, bringing us closer to cancer treatments.

“We are delighted that Cancer Research UK is supporting our research into the biology of cancer, as understanding cancer fully will let us develop the most effective treatments.”

Professor Phil Hannaford, Vice-Principal for Research and Knowledge Exchange, said the new grant would enable the Donaldson laboratory, established at the University of Aberdeen in 2003, to continue its pioneering work into the causes of cancer.

“The University of Aberdeen is undertaking important research in the fight against cancer from understanding the development of the disease to improved diagnosis and treatment, cancer follow-up and survivorship care.

“Understanding how tumours develop in the first place is an important cornerstone of the fight against cancer and this grant from Cancer Research UK will enable an important area of that research to flourish within a world-class research environment.”

Professor Donaldson explained that work in the laboratory would ‘start from the beginning’ when it comes to the development of tumours. 

“We will be taking a bottom-up approach in the work we undertake in the lab, first to understand the basic biology of RIF1 and then to look at how it can be applied in a clinical setting to develop new therapies,” she said.

“The cell component RIF1 controls the repair and replication of DNA.   If these processes don’t occur or go wrong it can result in cancer. For cancer to grow cells need to multiply, and if we can work out how to stop this happening then it has great potential to improve cancer treatment.

“The component RIF1 is found in all types of cancer and is particularly frequently mutated in colon, endocrine and lung cancers—so it is vital that we improve our understanding. It is only through grants like this from Cancer Research UK—made possible by the support they receive from the public—that we can take forward the science needed to tackle the disease.” 

Search News

Browse by Month

2024

  1. Jan
  2. Feb There are no items to show for February 2024
  3. Mar There are no items to show for March 2024
  4. Apr There are no items to show for April 2024
  5. May There are no items to show for May 2024
  6. Jun There are no items to show for June 2024
  7. Jul There are no items to show for July 2024
  8. Aug There are no items to show for August 2024
  9. Sep There are no items to show for September 2024
  10. Oct There are no items to show for October 2024
  11. Nov There are no items to show for November 2024
  12. Dec There are no items to show for December 2024

2023

  1. Jan There are no items to show for January 2023
  2. Feb There are no items to show for February 2023
  3. Mar There are no items to show for March 2023
  4. Apr There are no items to show for April 2023
  5. May There are no items to show for May 2023
  6. Jun There are no items to show for June 2023
  7. Jul There are no items to show for July 2023
  8. Aug There are no items to show for August 2023
  9. Sep There are no items to show for September 2023
  10. Oct
  11. Nov There are no items to show for November 2023
  12. Dec

2022

  1. Jan
  2. Feb There are no items to show for February 2022
  3. Mar
  4. Apr There are no items to show for April 2022
  5. May
  6. Jun There are no items to show for June 2022
  7. Jul
  8. Aug
  9. Sep There are no items to show for September 2022
  10. Oct
  11. Nov There are no items to show for November 2022
  12. Dec There are no items to show for December 2022

2021

  1. Jan There are no items to show for January 2021
  2. Feb
  3. Mar
  4. Apr
  5. May
  6. Jun
  7. Jul
  8. Aug
  9. Sep
  10. Oct
  11. Nov
  12. Dec

2020

  1. Jan
  2. Feb
  3. Mar
  4. Apr
  5. May
  6. Jun
  7. Jul
  8. Aug There are no items to show for August 2020
  9. Sep There are no items to show for September 2020
  10. Oct There are no items to show for October 2020
  11. Nov
  12. Dec

2019

  1. Jan
  2. Feb
  3. Mar There are no items to show for March 2019
  4. Apr
  5. May
  6. Jun
  7. Jul
  8. Aug
  9. Sep
  10. Oct
  11. Nov
  12. Dec

2018

  1. Jan There are no items to show for January 2018
  2. Feb There are no items to show for February 2018
  3. Mar There are no items to show for March 2018
  4. Apr There are no items to show for April 2018
  5. May There are no items to show for May 2018
  6. Jun There are no items to show for June 2018
  7. Jul
  8. Aug
  9. Sep
  10. Oct
  11. Nov
  12. Dec

2017

  1. Jan
  2. Feb There are no items to show for February 2017
  3. Mar
  4. Apr
  5. May
  6. Jun
  7. Jul
  8. Aug There are no items to show for August 2017
  9. Sep
  10. Oct There are no items to show for October 2017
  11. Nov
  12. Dec There are no items to show for December 2017

2016

  1. Jan
  2. Feb
  3. Mar
  4. Apr
  5. May
  6. Jun
  7. Jul
  8. Aug There are no items to show for August 2016
  9. Sep
  10. Oct
  11. Nov There are no items to show for November 2016
  12. Dec

2014

  1. Jan
  2. Feb
  3. Mar
  4. Apr
  5. May
  6. Jun
  7. Jul
  8. Aug
  9. Sep There are no items to show for September 2014
  10. Oct
  11. Nov
  12. Dec

2012

  1. Jan There are no items to show for January 2012
  2. Feb There are no items to show for February 2012
  3. Mar There are no items to show for March 2012
  4. Apr There are no items to show for April 2012
  5. May There are no items to show for May 2012
  6. Jun There are no items to show for June 2012
  7. Jul There are no items to show for July 2012
  8. Aug There are no items to show for August 2012
  9. Sep
  10. Oct
  11. Nov There are no items to show for November 2012
  12. Dec There are no items to show for December 2012