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Health Economics Research Unit (HERU)

Professor Graeme MacLennan

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Professor Graeme MacLennan
Professor Graeme MacLennan
Professor Graeme MacLennan

Director (CHaRT)

About
Email Address
g.maclennan@abdn.ac.uk
Telephone Number
+44 (0)1224 438147
Office Address

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition
ORCiD

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - University of Aberdeen 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester). 

Research on making trials more efficient, collaborating with Trial Forge. 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking here

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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  • Effectiveness and cost-effectiveness of a peer-delivered, relational, harm reduction intervention to improve mental health, quality of life, and related outcomes, for people experiencing homelessness and substance use problems: protocol for the ‘SHARPS’ cluster randomised controlled trial

    Parkes, T., Carver, H., Boyd, J., Cotton, S., Breeman, S., Cooper, D., Forrest, M., Foster, R., Hawthorn, J., Hunt, K., Kilonzo, M., Matheson, C., Maxwell, M., Mercer, S. W., Pauly, B., Scotland, G., Steele, W., Sumnall, H., Wallace, J., Macaulay, L., MacLennan, G.
    Trials
    Contributions to Journals: Articles

  • ColoCap: determining the diagnostic accuracy of colon capsule endoscopy compared with standard colonoscopy in patients at risk of colorectal disease: a study protocol

    Ibrahim, H., Haritakis, M., Ballantine, L., McCormack, K., Cotton, S., Hudson, J., Atkin, K., Rogers, S., Nixon, L. S., Verghese, A., Holmes, H., Treweek, S., MacLennan, G., Dolwani, S., Gardner, G., Hurt, C., Watson, A. J. M., Turvill, J. L.
    BMJ Open, vol. 15, no. 9, e104661
    Contributions to Journals: Articles

  • Spirometry to manage asthma in children: a study protocol for a randomised controlled trial (SPIROMAC)

    Bell, V., Sergenson, N., Cotton, S., Emele, C. D., Thomas, R., Aucott, L., Forrest, M., Gaillard, E. A., Kennington, E., MacLennan, G., Sinha, I., Vadiveloo, T., Scott, N., Turner, S.
    Trials, vol. 26, 373
    Contributions to Journals: Articles

  • PUrE Randomised Controlled Trial 2: Clinical and Cost Effectiveness of Flexible Ureterorenoscopy and Percutaneous Nephrolithotomy for Lower-pole Stones of 10–25 mm

    Smith, D., Wiseman, O., Starr, K., Aucott, L., Hernández, R., Thomas, R., MacLennan, S., Clark, C. T., MacLennan, G., McRae, D., Bell, V., Cotton, S., Gall, Z., Turney, B., McClinton, S.
    European Urology Focus
    Contributions to Journals: Articles

  • Updated Systematic Review and Meta-analysis of Extracorporeal Shock Wave Lithotripsy, Flexible Ureterorenoscopy, and Percutaneous Nephrolithotomy for Lower Pole Renal Stones

    MacLennan, S., Wiseman, O. J., Smith, D., Starr, K., Aucott, L., Hernández, R. A., Manson, P., Thomas, R., Clark, C. T., MacLennan, G., McRae, D., Bell, V., Cotton, S., Gall, Z., Turney, B., McClinton, S.
    European Urology, vol. 88, no. 3, pp. 231-239
    Contributions to Journals: Review articles

  • Ten Year Follow-Up of a Multicentre Randomised Controlled Trial Assessing Clinical and Cost Effectiveness of Total Versus Partial Knee Replacement

    Beard, D. J., Davies, L. J., Cook, J. A., MacLennan, G., Hudson, J., Price, A., Carr, A. J., Little, M., Leal, J., Fitzpatrick, R., Murray, D., Campbell, M., TOPKAT Study Group
    The Lancet Rheumatology
    Contributions to Journals: Articles

  • Clinical and cost-effectiveness of percutaneous nephrolithotomy, flexible ureterorenoscopy and extracorporeal shockwave lithotripsy for lower pole stones: the PUrE RCTs

    Wiseman, O., Smith, D., Starr, K., Aucott, L., Hernández, R., Thomas, R., Maclennan, S., Clark, C. T., Maclennan, G., McRae, D., Bell, V., Cotton, S., Gall, Z., Turney, B., McClinton, S.
    Health Technology Assessment, vol. 29, no. 40
    Contributions to Journals: Articles

  • Secondary analysis of the Game of Stones trial for men with obesity: Examining moderator effects and exploratory outcomes

    Dombrowski, S. U., Hoddinott, P., Macaulay, L., O’Dolan, C., Swingler, J., Cotton, S., Avenell, A., Getaneh, A., Gray, C., Hunt, K., Kee, F., MacLean, A., McKinley, M. C., Torrens, C., Turner, K., Van der Pol, M., MacLennan, G.
    Obesity, vol. 33, no. 8, pp. 1432-1446
    Contributions to Journals: Articles

  • The PUrE Randomised Controlled Trial (RCT) 1: Clinical and cost-effectiveness of Flexible Ureterorenoscopy and Extracorporeal Shockwave Lithotripsy for lower pole stones ≤10mm.

    Wiseman, O. J., Smith, D., Starr, K., Aucott, L., Hernández, R. A., Thomas, R., MacLennan, S., Clark, C. T., MacLennan, G., McRae, D., Bell, V., Cotton, S., Gall, Z., Turney, B., McClinton, S.
    European Urology, vol. 88, no. 2, pp. 179-189
    Contributions to Journals: Articles

  • Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms: FUTURE, a superiority RCT and economic evaluation

    Abdel-Fattah, M., Chapple, C., Breeman, S., Cooper, D., Bell-Gorrod, H., Kuppanda, P., Guerrero, K. L., Dixon, S., Cotterill, N., Ward, K., Hashim, H., Monga, A., Brown, K., Drake, M., Gammie, A., Mostafa, A., Bruce, R., Bell, V., Kennedy, C., Evans, S., MacLennan, G., Norrie, J.
    Health Technology Assessment, vol. 29, no. 27
    Contributions to Journals: Articles
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