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Professor Graeme MacLennan

Professor Graeme MacLennan
Professor Graeme MacLennan
Professor Graeme MacLennan

Director (CHaRT)

About
Email Address
g.maclennan@abdn.ac.uk
Telephone Number
+44 (0)1224 438147
Office Address

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition
ORCiD

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the University of Aberdeen, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - University of Aberdeen 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available here on using instrumental variables in a surgery trial to address non-compliance. Collaborators were Jonathan Cook (Oxford), Tom Palmer (Lancaster), and Richard Emesley (Manchester). 

Research on making trials more efficient, collaborating with Trial Forge. 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking here

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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  • Survey on ureTEric draiNage post uncomplicaTed ureteroscopy (STENT)

    Bhatt, N. R., MacKenzie, K., Shah, T. T., Gallagher, K., Clement, K., Cambridge, W. A., Kulkarni, M., MacLennan, G., Manecksha, R. P., Wiseman, O. J., Mcclinton, S., Smith, D., Kasivisvanathan, V.
    BJUI Compass, vol. 2, no. 2, pp. 115-125
    Contributions to Journals: Articles

  • Psychological intervention, antipsychotic medication or a combined treatment for adolescents with a first episode of psychosis: the MAPS feasibility three-arm RCT

    Morrison, A. P., Pyle, M., Byrne, R., Broome, M., Freeman, D., Johns, L., James, A., Husain, N., Whale, R., MacLennan, G., Norrie, J., Hudson, J., Peters, S., Davies, L., Bowe, S., Smith, J., Shiers, D., Joyce, E., Jones, W., Hollis, C., Maughan, D.
    Health technology assessment (Winchester, England), vol. 25, no. 4, pp. 1-124
    Contributions to Journals: Articles

  • Open urethroplasty versus endoscopic urethrotomy for recurrent urethral stricture in men: the OPEN RCT

    Pickard, R., Goulao, B., Carnell, S., Shen, J., MacLennan, G., Norrie, J., Breckons, M., Vale, L., Whybrow, P., Rapley, T., Forbes, R., Currer, S., Forrest, M., Wilkinson, J., McColl, E., Andrich, D., Barclay, S., Cook, J., Mundy, A., N'Dow, J., Payne, S., Watkin, N.
    Contributions to Journals: Registered Reports

  • Surgical Treatment for Recurrent Bulbar Urethral Stricture: A Randomised Open-label Superiority Trial of Open Urethroplasty Versus Endoscopic Urethrotomy (the OPEN Trial)

    Goulao, B., Carnell, S., Shen, J., MacLennan, G., Norrie, J., Cook, J., McColl, E., Breckons, M., Vale, L., Whybrow, P., Rapley, T., Forbes, R., Currer, S., Forrest, M., Wilkinson, J., Andrich, D., Barclay, S., Mundy, A., N'Dow, J., Payne, S., Watkin, N., Pickard, R.
    European Urology, vol. 78, no. 4, pp. 572-580
    Contributions to Journals: Articles

  • Antipsychotic medication versus psychological intervention versus a combination of both in adolescents with first-episode psychosis (MAPS): a multicentre, three-arm, randomised controlled pilot and feasibility study

    Morrison, A. P., Pyle, M., Maughan, D., Johns, L., Freeman, D., Broome, M. R., Husain, N., Fowler, D., Hudson, J., MacLennan, G., Norrie, J., Shiers, D., Hollis, C., James, A., MAPS group
    The lancet. Psychiatry, vol. 7, no. 9, pp. 788-800
    Contributions to Journals: Articles

  • Mesh inlay, mesh kit or native tissue repair for women having repeat anterior or posterior prolapse surgery: randomised controlled trial (PROSPECT)

    Glazener, C., Breeman, S., Elders, A., Hemming, C., Cooper, K. G., Freeman, R. M., Smith, A., Hagen, S., Montgomery, I., Kilonzo, M., Boyers, D., McDonald, A., McPherson, G., MacLennan, G., Norrie, J., Reid, F. M., PROSPECT study group
    BJOG-An International Journal of Obstetrics and Gynaecology, vol. 127, no. 8, pp. 1002-1013
    Contributions to Journals: Articles

  • The clinical and cost effectiveness of surgical interventions for stones in the lower pole of the kidney: the percutaneous nephrolithotomy, flexible ureterorenoscopy and extracorporeal shockwave lithotripsy for lower pole kidney stones randomised controlled trial (PUrE RCT) protocol

    McClinton, S., Starr, K., Thomas, R., MacLennan, G., Lam, T., Hernandez, R., Pickard, R., Anson, K., Clark, T., MacLennan, S., Thomas, D., Smith, D., Turney, B., McDonald, A., Cameron, S., Wiseman, O.
    Trials, vol. 21, 479
    Contributions to Journals: Articles

  • Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT

    Beard, D. J., Davies, L. J., Cook, J. A., MacLennan, G., Price, A., Kent, S., Hudson, J., Carr, A., Leal, J., Campbell, H., Fitzpatrick, R., Arden, N., Murray, D., Campbell, M. K.
    Health technology assessment (Winchester, England), vol. 24, no. 20, pp. 1-98
    Contributions to Journals: Articles

  • Baseline Characteristics of Participants in the Treatment of Advanced Glaucoma Study: A Multicenter Randomized Controlled Trial

    King, A. J., Hudson, J., Fernie, G., Burr, J., Azuara-Blanco, A., Sparrow, J. M., Barton, K., Garway-Heath, D., Kernohan, A., MacLennan, G., TAGS Research Group
    American Journal of Ophthalmology, vol. 213, pp. 186-194
    Contributions to Journals: Articles

  • Surgical treatments for women with stress urinary incontinence: a systematic review of economic evidence

    Javanbakht, M., Moloney, E., Brazzelli, M., Wallace, S., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Imamura, M., Hudson, J., MacLennan, G., Vale, L., Craig, D.
    Systematic reviews , vol. 9, 85
    Contributions to Journals: Articles
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