The Cancer Imaging Group (CIG) is a multi-disciplinary group involving physicists, oncologists, surgeons, radiologists and histologists.
We have developed a suite of advanced and novel magnetic resonance (MR) methods for revealing pathophysiological processes in breast cancer. We have demonstrated that lactate concentration, a marker of aerobic glycolysis (AG), can be quantified using double quantum filtered (DQF) MR spectroscopy as a potential early response marker for treatment. We have illustrated that cellularity, an established histological marker for treatment efficacy, can be non-invasively quantified using q-space imaging (QSI). We have further shown that lipid composition may provide crucial information for early diagnosis, phenotype identification and treatment monitoring using a combination of DQF MR spectroscopy, DQF correlation spectroscopy (COSY) and advanced Dixon method.
Dr Jiabao He