Lecturer
- About
-
- Email Address
- w.zhan@abdn.ac.uk
- Office Address
R353, Fraser Noble Building
School of Engineering
King's College
University of Aberdeen
Aberdeen AB24 3UE, UK
- School/Department
- School of Engineering
Biography
Wenbo Zhan is a Lecturer in Biological Engineering in the School of Engineering. He received his undergraduate degrees from Xi’an Jiaotong University in 2008 and a master degree from Harbin Institute of Technology in 2010. He graduated from Imperial College London with his PhD degree in 2014 and then worked as a project consultant at Imperial College London and a postdoctoral research fellow at the National University of Singapore until 2016. Prior to joining the University of Aberdeen in 2019, he was a research associate at Imperial College London.
Qualifications
- PhD Chemical Engineering2014 - Imperial College London
- MSc Thermal Energy and Power Engineering2010 - Harbin Institute of Technology
- BEng Thermal Energy and Power Engineering2008 - Xi'an Jiaotong University
- BEc Finance2008 - Xi'an Jiaotong Univerisity
Memberships and Affiliations
- Internal Memberships
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- Overall coordinator of the School MSc individual projects
- Deputy coordinator of MSc Biomedical Engineering programme
- Member of School Postgraduate Education Committee
- External Memberships
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- Editorial Advisory Board member of Pharmaceutical Research, 12/2022-present
- Research
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Research Overview
Wenbo Zhan's research centres on biological engineering and bioprocessing, with a particular focus on the biomechanics and transport processes in biological and physiological systems.
- Multiscale modelling of drug delivery processes
- Soft tissue deformation
- Image-based analysis of cardiovascular fluid mechanics
Funding and Grants
- Injectable thermosensitive hydrogel for controlled drug release targeting resected glioblastoma, The Royal Society, PI, 01/10/2024 - 30/09/2025
- HyWay: Hydrogen production from waste, European Union & EPSRC, Co-I, 15/04/2024 - 14/04/2028
- Evaluation and optimisation of thermosensitive hydrogel for controllable drug delivery against brain tumour, The Royal Society of Edinburgh, PI, 01/02/2023 - 30/09/2023
- Image-based modelling and optimisation of convection-enhanced delivery for combination therapy against heterogeneous human brain tumour, The Royal Society, PI, 12/08/2022 - 11/08/2024
- Gender differences in sex hormone transport in abdominal aortic aneurysm, The Royal Society, PI, 31/03/2022 - 30/03/2024
- Optimisation of infusion catheter posture for improving convection-enhanced drug delivery to brain cancer, Children's Brain Tumour Drug Delivery Consortium, Children with Cancer UK, PI, 01/03/2022 - 30/09/2022
- Novel nanoparticle-embedded membranes for long-term bioactive SARS-CoV2 prevention, Grampian University Hospitals NHS Trust, Co-I, 01/04/2021 - 31/03/2023
- Multifunctional liquid crystals stabilised by hydrogen-bounding and their integration in new devices for energy harvesting, conversion and storage, The Royal Society of Edinburgh, Co-I, 23/10/2020 - 30/12/2021
- Teaching
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Teaching Responsibilities
Programme
MSc Biomedical Engineering programme
Course coordinator
- EG555L - Modelling of Biological Systems
- EG20H7 - Fluid Mechanics for Civil Engineers 1
- EG30H3 - Fluid Mechanics for Civil Engineers 2
- EG555N,EG59F1,EG59F2,EG59M2 - MSc Individual Project (all MSc programmes)
Course contributor
- EG555J - Research Methods for Bioengineers
- EG4578 - Group Design Project (Chemical Engineering)
Previous course
- EG504Q - Introduction to Engineering for Life Scientists
- Publications
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On the microstructurally driven heterogeneous response of brain white matter to drug infusion pressure
Biomechanics and Modeling in Mechanobiology, vol. 21, pp. 1299–1316Contributions to Journals: ArticlesEffects of tissue hydraulic permeability on intracerebral transport of interstitial fluid and nanoparticle-encapsulated drugs upon convection-enhanced delivery
9th World Congress of Biomechanics, pp. O-20123Contributions to Conferences: AbstractsNumerical modelling of nanoparticle-mediated drug delivery across blood-brain barrier using focused ultrasound
9th World Congress of Biomechanics, pp. P-2010Contributions to Conferences: Abstracts- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/18954/1/P_2010.pdf
Effect of tissue permeability on drug transport in brain tumour after pressure-driven infusion
Contributions to Conferences: Oral Presentations- [ONLINE] https://sfmm2022.org
Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour
Pharmaceutical Research, vol. 39, no. 5, pp. 877-892Contributions to Journals: ArticlesEffect of particle size and surface charge on nanoparticles diffusion in the brain white matter
Pharmaceutical Research, vol. 39, pp. 767–781Contributions to Journals: ArticlesMathematical modelling of nanoparticle-mediated topical drug delivery to skin tissue
International Journal of Pharmaceutics, vol. 611, 121322Contributions to Journals: ArticlesConvection Enhanced Delivery of Light Responsive Antigen Capturing Oxygen Generators for Chemo-Phototherapy Triggered Adaptive Immunity
AIChE 2021Contributions to Conferences: AbstractsAnti-angiogenic effect on convection-enhanced delivery of cytotoxic drugs
BioMedEng21Contributions to Conferences: AbstractsEffect of brain tissue anisotropy on convection-enhanced delivery of nanoparticles encapsulated carmustine
BioMedEng21Contributions to Conferences: Abstracts- [ONLINE] Conference Book of Abstracts
- [ONLINE] Conference site
Convection enhanced delivery of light responsive antigen capturing oxygen generators for chemo-phototherapy triggered adaptive immunity
Biomaterials, vol. 275, 120974Contributions to Journals: ArticlesCharacterization of Transport Properties of Drugs in Brain Tissue Using Computational Fluid Dynamics
Contributions to Conferences: Oral PresentationsParticle velocity measurement of binary mixtures in the riser of a circulating fluidized bed by the combined use of electrostatic sensing and high-speed imaging
Petroleum Science, vol. 17, no. 4, pp. 1159-1170Contributions to Journals: ArticlesEnhanced penetration of pro-apoptotic and anti-angiogenic micellar nanoprobe in 3D multicellular spheroids for chemophototherapy
Journal of Controlled Release, vol. 323, pp. 502-518Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jconrel.2020.05.005
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/16380/1/Mozhi_etal_JCR_Enhanced_AAM.pdf
- [ONLINE] View publication in Scopus
A pilot study of aortic hemodynamics before and after thoracic endovascular repair with a double-branched endograft
Medicine in Novel Technology and Devices, vol. 4, 100027Contributions to Journals: ArticlesEffects of Focused-Ultrasound-and-Microbubble-Induced Blood-Brain Barrier Disruption on Drug Transport under Liposome-Mediated Delivery in Brain Tumour: a Pilot Numerical Simulation Study
Pharmaceutics, vol. 12, no. 1, 69Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3390/pharmaceutics12010069
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13664/1/WZhan_Pharmaceutics_2020.pdf
- [ONLINE] View publication in Scopus
Convection enhanced delivery of anti-angiogenic and cytotoxic agents in combination therapy against brain tumour
European Journal of Pharmaceutical Sciences, vol. 141, 105094Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ejps.2019.105094
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/15228/1/Zhan_EurJPharmSci_AAM.pdf
- [ONLINE] View publication in Scopus
Convection Enhanced Delivery of Light Responsive Antigen Capturing Oxygen Generators for Photoimmunotherapy of Hypoxic Tumors
Contributions to Conferences: PapersEffect of Enhanced Cerebrospinal Fluid Flow on Drug Penetration in Convection Enhanced Delivery
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsDevelopment of Nanoparticles for Drug Delivery to Brain Tumor: The Effect of Surface Materials on Penetration Into Brain Tissue
Journal of Pharmaceutical Sciences, vol. 108, no. 5, pp. 1736-1745Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.xphs.2018.12.002
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Delivery of liposome encapsulated temozolomide to brain tumour: Understanding the drug transport for optimisation
International Journal of Pharmaceutics, vol. 557, pp. 280-292Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ijpharm.2018.12.065
- [ONLINE] View publication in Scopus
Effect of tissue permeability and drug diffusion anisotropy on convection-enhanced delivery
Drug Delivery, vol. 26, no. 1, pp. 773-781Contributions to Journals: ArticlesNeurosurgical Convection Enhanced Drug Delivery: Experiments and Modelling
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsOptimising Nanoparticle Property and Treatment Regimen for Improving Convection Enhanced Delivery of Doxorubicin to Brain Tumour
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsTowards a multiphysics modelling framework for thermosensitive liposomal drug delivery to solid tumour combined with focused ultrasound hyperthermia
Biophysics Reports, vol. 5, no. 1, pp. 43-59Contributions to Journals: Articles