BSc (Hons), MSc, PhD, CStat, FSS, FFPH, FSCT, FRSE, FMedSci
Chair in HSRU
Professor Marion Campbell is Professor of Health Services Research at the University of Aberdeen. She is also co-Director of the RCSEng Aberdeen Surgical Trials Centre. Marion is a medical statistician by training, a clinical trialist and methodologist. Her main research interests are in the design, conduct and analysis of clinical trials especially complex trial design and the design and conduct of surgical and device trials. She has published widely on clinical trials methodology including on cluster randomised trials, design of trials of surgical interventions, pragmatic trials and trials reporting. She has served on many national and international funding agencies and committees and is an elected Fellow of the Academy of Medical Sciences, the Royal Society of Edinburgh, the Faculty of Public Health, and the International Society for Clinical Trials and is a previous NIHR senior investigator.
Previously Marion was Vice-Principal (Research) for the University of Aberdeen. In this role, she had primary responsibility for promoting the University's research ambitions, ensuring effective delivery of the University's strategic objectives for research. and for enabling a research context for academic colleagues to deliver world-leading, impactful research. She also led on the establishment of interdisciplinary research across the institution. Prior to this, Marion was Dean of Research for Life Sciences and Medicine following ten years as Director of the Scottish government core-funded Health Services Research Unit.
Marion graduated with an honours degree in Statistics from the University of Aberdeen and subsequently gained an MSc in Statistics and PhD in Public Health. Following early career appointments within the National Health Service in the fields of Operational Research and Statistics of Medical Audit, she joined the University of Aberdeen in 1993.
Chair. MRC Better Methods Better Research Panel
Member of REF2021 UoA2 sub-panel
Marion’s main research interests are in the design, conduct and analysis of clinical trials especially complex trial design and the design and conduct of surgical and device trials. She has also published widely on clinical trials methodology including on cluster randomised trials, design of trials of non-pharmacological interventions, pragmatic trials and trials reporting.
Some examples of current and recent research include:
REINFORCE: The NIHR-funded REINFORCE study aims to evaluation the introduction and scale up of robot-assisted surgery across the NHS. Further information is available at: https://www.abdn.ac.uk/hsru/what-we-do/research/projects/reinforce-291
UK-REBOA: The NIHR-funded UK-REBOA trial aims to establish the clinical and cost-effectiveness of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA), in addition to standard major trauma centre treatment, for the treatment of patients with life-threatening torso haemorrhage. The trial is currently live across major trauma centres in England. Further information is available on the trial website: https://w3.abdn.ac.uk/hsru/REBOA/Public/Public/index.cshtml
TOPKAT: The NIHR-funded TOPKAT trial is investigating the clinical and cost effectiveness of partial (PKR) vs total (THR) knee replacements. The trial recruited 528 patients from across the UK. Five year results have been published in the Lancet (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)31281-4/fulltext) and showed that PKR has similar, if not a slightly better clinical outcome than TKR. More importantly, the economic benefit of using PKR is substantial. Patients are now being followed up to 10 years.
CLASS: The NIHR-funded CLASS trial is assessing the clinical and cost-effectiveness of three treatment modalities for the treatment of varicose veins: a) foam; b) EVLA with subsequent foam to varicosities when required; and c) surgery. A total of 798 adult patients were recruited into the trial and randomised to one of the treatment options. Six weeks results have been published in the NEJM (http://www.nejm.org/doi/full/10.1056/NEJMoa1400781). Five year follow-up is now complete.
KAT: The NIHR-funded KAT trial, explores different knee replacement surgery options (the effects of patellar resurfacing, mobile bearings and metal backing were investigated). A total of 116 surgeons in 34 UK centres participated and 2352 participants were randomised. Ten year outcomes were previously published (https://www.journalslibrary.nihr.ac.uk/hta/hta18190/#/abstract); long term follow up to 20 years is underway.
Applied Health Sciences
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Comparing outcomes in renal replacement therapy: how should we correct for case mix?American Journal of Kidney Diseases, vol. 31, no. 3, pp. 473-8Contributions to Journals: Articles
Direct disclosure of bone density results to patients: Effect on knowledge of osteoporosis risk and anxiety levelOsteoporosis International, vol. 8, pp. 584-590Contributions to Journals: Articles
Randomized trial of osteoporosis screening: Use of hormone replacement therapy and quality-of-life resultsArchives of Internal Medicine, vol. 157, no. 18, pp. 2121-2125Contributions to Journals: Articles
Alcohol consumption and age of maternal menopause are associated with menopause onsetMaturitas, vol. 26, no. 1, pp. 21-25Contributions to Journals: Articles
Health Check ups in General Practice: A patient perspective.Health Bulletin, vol. 54, pp. 241-247Contributions to Journals: Articles
Prediction of perimenopausal fractures by bone mineral density and other risk factorsJournal of Bone and Mineral Research, vol. 11, no. 2, pp. 293-297Contributions to Journals: Articles
Survival on renal replacement therapy in Europe: is there a 'centre effect'?Nephrology Dialysis Transplantation, vol. 11, no. 2, pp. 300-7Contributions to Journals: Articles
Complementary therapies in a local healthcare setting. Part1: Is there real public demand?Complimentary Therapies in Medicine, vol. 4, pp. 39-42Contributions to Journals: Articles