People

Professor Miriam Brazzelli

Professor Miriam Brazzelli
Professor Miriam Brazzelli
Professor Miriam Brazzelli

Personal Chair

About
Email Address
m.brazzelli@abdn.ac.uk
Telephone Number
+44 (0)1224 438404
Office Address
Floor 2 Room 204 Health Sciences Building
Foresterhill Campus
Foresterhill
AB25 2ZD

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School/Department
School of Medicine, Medical Sciences and Nutrition
ORCiD

Biography

Miriam Brazzelli obtained her degree in Physiotherapy from the San Carlo Borromeo Physiotherapy School in 1988, followed by an Honours degree in Psychology (Cognitive Psychology) from the University of Turin, Italy, in 1997. She began her career with appointments in the field of physiotherapy and neuropsychology. In January 1999, she joined the Unit, and in 2005 was awarded a Research Fellowship by the Chief Scientist Office of the Scottish Executive Health Department, which focused on methods for conducting systematic reviews of diagnostic test accuracy studies. She earned her PhD in Public Health Sciences from the University of Edinburgh in 2011. She re-joined the Unit in February 2012 as the lead of the Knowledge Synthesis Programme within the wider Healthcare Assessment Programme. Her research focuses on complex evidence syntheses and health technology assessments, with the aim of evaluating the clinical and cost-effectiveness of both new and existing healthcare, social care and public health interventions.

Qualifications

  • Degree Physiotherapy 
    1988 - Physiotherapy School, Azienda Ospedaliera San Carlo Borromeo, Milan, Italy 
  • BSc, Hons Psychology 
    1997 - University of Turin, Italy 
  • PhD by Research, Public Health Sciences 
    2011 - University of Edinburgh 

Memberships and Affiliations

Internal Memberships

Member of the ACE Public Engagement Group.

Member of the Institute of Applied Health Sciences (IAHS) Equality, Diversity and Inclusion Group.

External Memberships

Member of the NIHR HTA Commissioning Funding Committee (since May 2023)

Latest Publications

  • Duration of wound coverage for the prevention of surgical site infections after surgery: A systematic review of current evidence with meta-analysis of randomised controlled trials

    Cruickshank, M., Brazzelli, M., Loudon, K., Ramsay, G.
    International Wound Journal
    Contributions to Journals: Articles

  • Concordance between automated/semi-automated measurement and manual assessment of mammographic breast density in individuals undergoing breast cancer screening: A systematic review

    Robertson, C., Cooper, D., Duggan, S. N., Manson, P., Imamura, M., Hernández, R. A., Clarke, M., Treweek, S., Brazzelli, M.
    Journal of Medical Screening
    Contributions to Journals: Articles

  • Trial informativeness across research practices: Initial findings from a mapping exercise

    Prowse, S., Brazzelli, M., Bain, J., Treweek, S.
    Journal of Clinical Epidemiology, 112274
    Contributions to Journals: Articles

  • DECODE: An innovative tool to aid cross-linguistic neuropsychological assessment

    Calia, C., Della Sala, S., O’Donald, F., Forrest, M., Brazzelli, M.
    Clinical Neuropsychologist
    Contributions to Journals: Articles

  • Clinical utility of biomarkers for outcomes prediction in adults with suspected sepsis presenting to the emergency department: a synthesis of current evidence

    Imamura, M., Duggan, S. N., Vadiveloo, T., Cooper, J. G., Kaye, C. T., Manson, P., Virgili, G., Aucott, L., Clarke, M., Brazzelli, M.
    Health Technology Assessment, pp. 1-90
    Contributions to Journals: Articles

View My Publications

Research

Research Overview

My research focuses on complex evidence syntheses and health technology assessments (HTAs), aimed at evaluating the clinical and cost-effectiveness of both new and established healthcare interventions. I have expertise in conducting various types of systematic reviews - including quantitative, qualitative, and mixed-methods reviews - across a wide range of topics in healthcare, public health, and social care. This includes work on interventions targeting specific clinical conditions, as well as broader evaluations and policy-relevant evidence syntheses. My work supports evidence-informed decision-making by synthesising diverse forms of evidence to address complex questions in real-world settings.

Research Areas

Applied Health Sciences

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Research Specialisms

  • Health Sciences
  • Applied Science
  • Neuroscience

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Collaborations

ABEC, the Aberdeen Belfast Collaboration, is a collaborative initiative between the University of Aberdeen and Queen's University Belfast

Teaching

Teaching Responsibilities

Contributing to the PU5526 Systematic Reviewing course by delivering lectures and marking students' assignments.

Publications

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  • Physical Fitness Training for Patients with Stroke

    Saunders, D. H., Sanderson, M., Hayes, S., Kilrane, M., Greig, C. A., Brazzelli, M., Mead, G. E.
    Stroke, vol. 47, no. 9, pp. e219-e220
    Contributions to Journals: Articles

  • A randomised controlled trial comparing laparoscopic cholecystectomy with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated symptomatic gallstones. (C-Gall trial)

    Malik, M., Murchie, P., Gillies, K., Brazzelli, M. G., Avenell, A., Hernandez, R., Norrie, J., Blazeby, J., Ramsay, C., Ahmed, I.
    International Surgical Congress of the Association-of-Surgeons-of-Great-Britain-and-Ireland, pp. 195-196
    Contributions to Journals: Abstracts

  • Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review

    Cruickshank, M., Henderson, L., MacLennan, G., Fraser, C., Campbell, M., Blackwood, B., Gordon, A., Brazzelli, M.
    Health Technology Assessment, vol. 20, no. 25, pp. 0-120
    Contributions to Journals: Literature Reviews

  • Author Response - ABCD2 score and secondary stroke prevention: Meta-analysis and effect per 1,000 patients triaged

    Wardlaw, J. M., Brazzelli, M., Chappell, F., Dennis, M. S., Sandercock, P. A.
    Neurology, vol. 86, no. 7, pp. 697
    Contributions to Journals: Letters

  • Physical fitness training for stroke patients

    Sanders, D. H., Sanderson, M., Hayes, S., Kilrane, M., Greig, C. A., Brazzelli, M., Mead, G. E.
    Cochrane Database of Systematic Reviews, no. 3, pp. 1-411
    Contributions to Journals: Literature Reviews

  • The clinical and cost-effectiveness of open mesh repairs in adults presenting with a clinically diagnosed unilateral, primary inguinal hernia who are operated in an elective setting: systematic review and economic evaluation

    Sharma, P., Boyers, D., Scott, N. W., Hernandez, R. A., Fraser, C. M., Cruickshank, M., Ahmed, I., Ramsay, C. R., Brazzelli, M. G.
    Health Technology Assessment, vol. 19, no. 92, pp. i - 141
    Contributions to Journals: Literature Reviews

  • Collagenase clostridium histolyticum for the treatment of Dupuytren’s contracture: systematic review and economic evaluation

    Brazzelli, M., Cruickshank, M., Tassie, E., McNamee, P., Robertson, C., Elders, A., Fraser, C., Hernandez, R., Lawrie, D., Ramsay, C.
    Health Technology Assessment, vol. 19, no. 90, pp. 1-202
    Contributions to Journals: Articles

  • ABCD2 score and secondary stroke prevention: Meta-analysis and effect per 1,000 patients triaged

    Wardlaw, J. M., Brazzelli, M., Chappell, F. M., Miranda, H., Shuler, K., Sandercock, P. A. G., Dennis, M. S.
    Neurology, vol. 85, no. 4, pp. 373-380
    Contributions to Journals: Articles

  • Ablative therapy for people with localised prostate cancer: a systematic review and economic evaluation

    Ramsay, C. R., Adewuyi, T. E., Gray, J., Hislop, J., Shirley, M. D., Jayakody, S., MacLennan, G., Fraser, C., MacLennan, S., Brazzelli, M., N'Dow, J., Pickard, R., Robertson, C., Rothnie, K., Rushton, S. P., Vale, L., Lam, T. B.
    Health Technology Assessment, vol. 19, no. 49, pp. 1-524
    Contributions to Journals: Articles

  • Is self-monitoring an effective option for people receiving long-term vitamin K antagonist therapy? A systematic review and economic evaluation

    Sharma, P., Scotland, G., Cruickshank, M., Tassie, E., Fraser, C., Burton, C. D., Croal, B., Ramsay, C. R., Brazzelli, M. G.
    BMJ Open, vol. 5, no. 6, e007758
    Contributions to Journals: Articles

  • Assessment of diagnostic tests and the impact on decision making: self-monitoring of oral anticoagulation therapy: Oral presentation

    Sharma, P., Scotland, G. S., Cruickshank, M., Tassie, E., Fraser, C. M., Burton, C. D., Croal, B. L., Ramsay, C. R., Brazzelli, M. G.
    Contributions to Conferences: Other Contributions

  • The clinical effectiveness and cost-effectiveness of point-of-care tests (CoaguChek system, INRatio2 PT/INR monitor and ProTime Microcoagulation system) for the self-monitoring of the coagulation status of people receiving long-term vitamin K antagonist therapy, compared with standard UK practice: systematic review and economic evaluation

    Sharma, P., Scotland, G. S., Cruickshank, M., Tassie, E., Fraser, C., Burton, C. D., Croal, B., Ramsay, C. R., Brazzelli, M.
    Health Technology Assessment, vol. 19, no. 48, pp. 1-172
    Contributions to Journals: Articles

  • Systematic review of the clinical and cost effectiveness of cholecystectomy versus observation/conservative management for uncomplicated symptomatic gallstones or cholecystitis

    Brazzelli, M., Cruickshank, M., Kilonzo, M., Ahmed, I., Stewart, F., McNamee, P., Elders, A., Fraser, C., Avenell, A., Ramsay, C.
    Surgical Endoscopy, vol. 29, no. 3, pp. 637-647
    Contributions to Journals: Articles

  • Optic nerve head and fibre layer imaging for diagnosing glaucoma

    Michelessi, M., Lucenteforte, E., Oddone, F., Brazzelli, M. G., Parravano, M., Franchi, S., Ng, S. M., Virgili, G.
    Cochrane Database of Systematic Reviews, no. 11, CD008803
    Contributions to Journals: Literature Reviews

  • Clinical effectiveness and cost-effectiveness of cholecystectomy compared with observation/conservative management for preventing recurrent symptoms and complications in adults presenting with uncomplicated symptomatic gallstones or cholecystitis: a systematic review and economic evaluation

    Brazzelli, M., Cruickshank, M., Kilonzo, M., Ahmed, I., Stewart, F., McNamee, P., Elders, A., Fraser, C., Avenell, A., Ramsay, C.
    Health Technology Assessment, vol. 18, no. 55, pp. 1-102
    Contributions to Journals: Articles

  • An assessment of the cost-effectiveness of magnetic resonance, including diffusion-weighted imaging in patients with transient ischaemic attack and minor stroke: a systematic review, meta-analysis and economic evaluation

    Wardlaw, J., Brazzelli, M., Miranda, H., Chappell, F., McNamee, P., Scotland, G. S., Quayyum, Z., Martin, D., Shuler, K., Sandercock, P., Dennis, M.
    Health Technology Assessment, vol. 18, no. 27, pp. 1-368, v-xxvi
    Contributions to Journals: Articles

  • Physical Fitness Training for Patients With Stroke: An Updated Review

    Saunders, D. H., Sanderson, M., Brazzelli, M., Greig, C. A., Mead, G. E.
    Stroke, vol. 45, no. 4, pp. e54-e55
    Contributions to Journals: Literature Reviews

  • Diffusion-weighted imaging and diagnosis of transient ischemic attack

    Brazzelli, M., Chappell, F. M., Miranda, H., Shuler, K., Dennis, M., Sandercock, P. A. G., Muir, K., Wardlaw, J. M.
    Annals of Neurology, vol. 75, no. 1, pp. 67-76
    Contributions to Journals: Articles

  • Transcranial Doppler sonography for detecting stenosis or occlusion of intracranial arteries in people with acute ischaemic stroke

    Mattioni, A., Brazzelli, M., Cenciarelli, S., Mazzoli, T., Del Sette, M., Gandolfo, C., Marinoni, M., Finocchi, C., Saia, V., Eusebi, P., Sandercock, P. A. G., Ricci, S.
    Cochrane Database of Systematic Reviews, no. 9, pp. 1-15
    Contributions to Journals: Literature Reviews

  • Clinical and imaging services for TIA and minor stroke: results of two surveys of practice across the UK

    Brazzelli, M., Shuler, K., Quayyum, Z., Hadley, D., Muir, K., McNamee, P., De Wilde, J., Dennis, M., Sandercock, P., Wardlaw, J. M.
    BMJ Open, vol. 3, no. 8, 3359
    Contributions to Journals: Articles

  • Physical fitness training for stroke patients

    Saunders, D. H., Sanderson, M., Brazzelli, M., Greig, C. A., Mead, G. E.
    Cochrane Database of Systematic Reviews, no. 10, CD003316
    Contributions to Journals: Literature Reviews

  • Physical fitness training for patients with stroke: updated review

    Brazzelli, M. G., Saunders, D. H., Greig, C. A., Mead, G. E.
    Stroke, vol. 43, no. 4, pp. e39-e40
    Contributions to Journals: Articles

  • Behavioural and cognitive interventions with or without other treatments for the management of faecal incontinence in children

    Brazzelli, M. G., Griffiths, P. V., Cody, J. D., Tappin, D.
    Cochrane Database of Systematic Reviews, no. 12, CD002240
    Contributions to Journals: Articles

  • Physical fitness training for stroke patients

    Brazzelli, M., Saunders, D. H., Greig, C. A., Mead, G. E.
    Cochrane Database of Systematic Reviews, no. 11, CD003316
    Contributions to Journals: Literature Reviews

  • Evidence-based guideline: the role of diffusion and perfusion MRI for the diagnosis of acute ischemic stroke: report of the Therapeutics and Technology Subcommittee of the American Academy of Neurology

    Brazzelli, M. G., Sandercock, P., Wardlaw, J.
    Neurology, vol. 76, no. 23, pp. 2036-2038
    Contributions to Journals: Letters

  • MRI versus CT for detection of acute vascular lesions in patients presenting with stroke symptoms

    Brazzelli, M., Sandercock, P. A., Celani, M. G., Righetti, E., Chappell, F. M., Arestis, N., Wardlaw, J. M., Deeks, J. J.
    Contributions to Journals: Short Survey

  • A systematic review of clinical trials of pharmacological interventions for acute ischaemic stroke (1955-2008) that were completed, but not published in full

    Gibson, L. M., Brazzelli, M. G., Thomas, B. M., Sandercock, P. A. G.
    Trials, vol. 11, 43
    Contributions to Journals: Articles

  • Optic nerve head and fibre layer imaging for diagnosing glaucoma

    Oddone, F., Virgili, G., Parravano, M., Brazzelli, M. G., Novielli, N., Michelessi, M.
    Cochrane Database of Systematic Reviews, no. 11
    Contributions to Journals: Literature Reviews

  • Magnetic resonance imaging versus computed tomography for detection of acute vascular lesions in patients presenting with stroke symptoms

    Brazzelli, M. G., Sandercock, P. A. G., Chappell, F. M., Celani, M. G., Righetti, E., Arestis, N., Wardlaw, J. M., Deeks, J. J.
    Cochrane Database of Systematic Reviews, no. 4, CD007424
    Contributions to Journals: Literature Reviews

  • No evidence of bias in the process of publication of diagnostic accuracy studies in stroke submitted as abstracts

    Brazzelli, M., Lewis, S. C., Deeks, J. J., Sandercock, P. A. G.
    Journal of Clinical Epidemiology, vol. 62, no. 4, pp. 425-430
    Contributions to Journals: Articles

  • Developing a sensitive search strategy in MEDLINE to retrieve studies on assessment of the diagnostic performance of Imaging techniques

    Astin, M. P., Brazzelli, M. G., Fraser, C. M., Counsell, C. E., Needham, G., Grimshaw, J. M.
    Radiology, vol. 247, no. 2, pp. 365-373
    Contributions to Journals: Articles

  • Doppler ultrasound, angiography, MR angiography, and contrast-enhanced MR angiography versus intra-arterial angiography for moderate and severe stenosis in symptomatic patients.

    Chappell, F., Wardlaw, J., Brazzelli, M. G., Best, J.
    Cochrane Database of Systematic Reviews, no. 4
    Contributions to Journals: Literature Reviews

  • Systematic review of the effectiveness and cost-effectiveness of HealOzone® for the treatment of occlusal pit/fissure caries and root caries

    Brazzelli, M., McKenzie, L., Fielding, S., Fraser, C., Clarkson, J., Kilonzo, M., Waugh, N.
    Health Technology Assessment, vol. 10, no. 16, pp. iii-50
    Contributions to Journals: Review articles

  • Efficicacy and safety of sacral nerve stimulation for urinary urge incontinence: a systematic review

    Brazzelli, M. G., Murray, A. C., Fraser, C. M.
    Journal of Urology, vol. 175, no. 3/1, pp. 835-41
    Contributions to Journals: Articles

  • Public health interventions to prevent early childhood caries: a systematic review

    Poobalan, A. S., Brazzelli, M. G., Aucott, L. S., Smith, W. C. S., Helms, P. J. B.
    Journal of Epidemiology and Community Health, vol. 59, no. Suppl 1, pp. A26-A27
    Contributions to Journals: Articles

  • Systematic review of the prognostic effectiveness of SPECT myocardial perfusion scintigraphy in patients with suspected or known coronary artery disease and following myocardial infarction

    Mowatt, G., Brazelli, M., Gemmell, H., Hillis, G. S., Metcalfe, M., Vale, L., Aberdeen Technology Assessment Review (TAR) Group
    Nuclear Medicine Communications, vol. 26, no. 3, pp. 217-229
    Contributions to Journals: Articles

  • Prevention of Early Childhood Caries: A Systematic Review.

    Poobalan, A., Brazzelli, M., Aucott, L., Smith, W. C. S., Helms, P.
    Contributions to Conferences: Papers

  • The effectiveness of metal on metal hip resurfacing: a systematic review of the available evidence published before 2002

    Wyness, L., Vale, L., McCormack, K., Grant, A., Brazzelli, M.
    BMC Health Services Research, vol. 4, 39
    Contributions to Journals: Articles

  • Systematic review of the effectiveness and cost-effectiveness, and economic evaluation, of myocardial perfusion scintigraphy for the diagnosis and management of angina and myocardial infarction

    Mowatt, G., Vale, L., Brazzelli, M., Hernandez, R., Murray, A., Scott, N., Fraser, C., McKenzie, L., Gemmell, H., Hillis, G., Metcalfe, M.
    Health Technology Assessment, vol. 8, no. 30, pp. iii-iv, 1-207
    Contributions to Journals: Articles

  • Public Health interventions to prevent Early Childhood Caries.

    Poobalan, A., Brazzelli, M., Aucott, L., Smith, W., Helms, P.
    Contributions to Conferences: Papers

  • Systematic review of the efficacy and safety of sacral nerve stimulation for urinary urge incontinence and urgency-frequency

    Brazzelli, M. G., Murray, A. C., Fraser, C. M., Grant, A. M.
    Review Body Report submitted to the Interventional Procedures Programme, National Institute for Clinical Excellence. University of Aberdeen, Health Services Research Unit, 2004. Available from: http://www.nice.org.uk/docref.asp?d=105933&c=56779&l=1: Unknown Publisher
    Books and Reports: Other Reports

  • Making the Best Use of Department of Clinical Radiology. Guidelines for Doctors

    Brazzelli, M. G., Astin, M. P.
    Royal College of Radiologists, London
    Books and Reports: Books

  • Drug treatment for faecal incontinence in adults

    Cheetham, M. J., Brazzelli, M., Norton, C. C., Glazener, C. M. A.
    Cochrane Database of Systematic Reviews, no. 3, CD002116
    Contributions to Journals: Articles

  • A systematic review of the effectiveness and cost-effectiveness of metal-on-metal hip resurfacing arthroplasty for treatment of hip disease

    Vale, L. D., Wyness, L., McKenzie, L., McCormack, K., Brazzelli, M. G., Stearns, S. C.
    Health Technology Assessment, vol. 6, no. 15, pp. 1-109
    Contributions to Journals: Articles

  • Absorbent products for containing urinary and/or fecal incontinence in adults

    Brazzelli, M. G., Shirran, E. A., Vale, L. D.
    Journal of Wound , Ostomy , & Continence Nursing, vol. 29, no. 1, pp. 45-54
    Contributions to Journals: Articles

  • Review: behavioural interventions plus laxatives are effective for defaecation disorders in children, but biofeedback does not add benefit

    Brazzelli, M. G., Griffiths, P.
    Evidence-Based Nursing, vol. 5, no. 3
    Contributions to Journals: Articles

  • Behavioural and cognitive interventions with or without other treatments for defaecation disorders in children

    Brazzelli, M., Griffiths, P.
    Cochrane Database of Systematic Reviews, no. 4
    Contributions to Journals: Articles

  • How to identify and assess evidence from diagnostic studies of imaging

    Brazzelli, M. G., Astin, M. P., Needham, G.
    Information pack on how to develop guidelines for 'making the best use of a department of clinical radiology - 5th edition (MBUR5): Unknown Publisher
    Books and Reports: Commissioned Reports

  • Management of faecal incontinence and constipation in adults with central neurological diseases

    Coggrave, M., Wiesel, P., Norton, C., Brazzelli, M.
    Cochrane Database of Systematic Reviews, no. 1, CD002115
    Contributions to Journals: Articles

  • Reducing the burden of faecal incontinence: a systematic review of controlled trials: final report to the NHS R&D Complex Disabilities Programme

    Grant, A. M., Norton, C., Hosker, G., Glazener, C. M. A., Vale, L. D., Bachoo, P., Brazzelli, M. G., Cheetham, M., Cody, D. J., Griffiths, P., Shirran, E. A.
    NHS
    Books and Reports: Commissioned Reports
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