Professor Miriam Brazzelli

Professor Miriam Brazzelli
Professor Miriam Brazzelli
Professor Miriam Brazzelli

Personal Chair

About
Email Address
m.brazzelli@abdn.ac.uk
Telephone Number
+44 (0)1224 438404
Office Address
Floor 2 Room 204 Health Sciences Building
Foresterhill Campus
Foresterhill
AB25 2ZD

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School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Miriam Brazzelli obtained her degree in Physiotherapy from the San Carlo Borromeo Physiotherapy School in 1988, followed by an Honours degree in Psychology (Cognitive Psychology) from the University of Turin, Italy, in 1997. She began her career with appointments in the field of physiotherapy and neuropsychology. In January 1999, she joined the Unit, and in 2005 was awarded a Research Fellowship by the Chief Scientist Office of the Scottish Executive Health Department, which focused on methods for conducting systematic reviews of diagnostic test accuracy studies. She earned her PhD in Public Health Sciences from the University of Edinburgh in 2011. She re-joined the Unit in February 2012 as the lead of the Knowledge Synthesis Programme within the wider Healthcare Assessment Programme. Her research focuses on complex evidence syntheses and health technology assessments, with the aim of evaluating the clinical and cost-effectiveness of both new and existing healthcare, social care and public health interventions.

Qualifications

  • Degree Physiotherapy 
    1988 - Physiotherapy School, Azienda Ospedaliera San Carlo Borromeo, Milan, Italy 
  • BSc, Hons Psychology 
    1997 - University of Turin, Italy 
  • PhD by Research, Public Health Sciences 
    2011 - University of Edinburgh 

Memberships and Affiliations

Internal Memberships

Member of the ACE Public Engagement Group.

Member of the Institute of Applied Health Sciences (IAHS) Equality, Diversity and Inclusion Group.

External Memberships

Member of the NIHR HTA Commissioning Funding Committee (since May 2023)

Latest Publications

  • Supplemental imaging modalities for breast cancer screening in women with dense breasts: A systematic review with economic considerations

    Duggan, S. N., Azharuddin, M., Hernández, R., Robertson, C., Cooper, D., McCall, E., Manson, P., Virgili, G., Clarke, M., Treweek, S., Brazzelli, M.
    Breast, vol. 85, 104668
    Contributions to Journals: Articles
  • Trifluridine-tipiracil with bevacizumab for treating metastatic colorectal cancer after 2 systemic treatments [ID6298]: NICE Single Technology Appraisal

    Cruickshank, M., Kilonzo, M., Ayansina, D., Kumar, S., Manson, P., Brazzelli, M., Samuel, L., Boyers, D.
    Commissioned by National Institute for Health and Care Excellence (NICE). Aberdeen HTA Group
    Books and Reports: Commissioned Reports
  • Effects of Pharmacologic and Nonpharmacologic Interventions for the Management of Sleep Problems in People With Fibromyalgia: Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

    Hudson, J., Imamura, M., Robertson, C., Whibley, D., Aucott, L., Gillies, K., Manson, P., Dulake, D., Abhishek, A., Tang, N., Macfarlane, G., Brazzelli, M.
    Arthritis Care & Research, vol. 77, no. 9, pp. 1095-1105
    Contributions to Journals: Review articles
  • Tackling health inequalities in cancer screening: Experiences of Eastern European and African communities in Northeast Scotland

    Prowse, S., Treweek, S., Larrea, M. J. P., Brazzelli, M., Uribe, A.
    Cancer Medicine, vol. 14, no. 18, e71236
    Contributions to Journals: Articles
  • What are the influences on women’s preferences and decision-making when planning mode of birth in high-income countries? A qualitative systematic review

    Cruickshank, M. D., Robertson, C., Brazzelli, M. G., Ekong, A. I., Ade Pgce, M., Mcdonagh Hull, P., Manson, P. D., Bick, D. E., Williams, D. O., Taylor, G., Ward, L. A., Kilonzo, M. M., Fairley, T. E., Bhattacharya, S., Locock, L., Rzewuska Diaz, M., Black, M. E.
    AJOG Global Reports, 100556
    Contributions to Journals: Articles

View My Publications

Research

Research Overview

My research focuses on complex evidence syntheses and health technology assessments (HTAs), aimed at evaluating the clinical and cost-effectiveness of both new and established healthcare interventions. I have expertise in conducting various types of systematic reviews - including quantitative, qualitative, and mixed-methods reviews - across a wide range of topics in healthcare, public health, and social care. This includes work on interventions targeting specific clinical conditions, as well as broader evaluations and policy-relevant evidence syntheses. My work supports evidence-informed decision-making by synthesising diverse forms of evidence to address complex questions in real-world settings.

Research Areas

Applied Health Sciences

Research Specialisms

  • Health Sciences
  • Applied Science
  • Neuroscience

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Collaborations

ABEC, the Aberdeen Belfast Collaboration, is a collaborative initiative between the University of Aberdeen and Queen's University Belfast

Teaching

Teaching Responsibilities

Contributing to the PU5526 Systematic Reviewing course by delivering lectures and marking students' assignments.

Publications

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  • Lanadelumab for preventing recurrent attacks of hereditary angioedema.

    Robertson, C., Walker, A., Jacobsen, E., Aucott, L., Herriot, R., Scotland, G., Brazzelli, M.
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports
  • Lorlatinib for previously treated ALK-positive advanced non-small-cell lung cancer

    Robertson, C., Fielding, S., Walker, A., Kopasker, D., Vadiveloo, T., Manson, P., Price, G., Brazzelli, M., Scotland, G.
    Commissioned by National Institute for Health and Care Excellence. Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence
    Books and Reports: Commissioned Reports
  • Risankizumab for treating moderate to severe plaque psoriasis

    Imamura, M., Cooper, D., Hernández, R. A., Ormerod, A., Scotland, G., Brazzelli, M., Aberdeen HTA Group
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports
  • The ARCHITECT and Alinity urine NGAL assays, urine NephroCheck test, and urine and plasma NGAL tests to help assess the risk of acute kidney injury in people who are being considered for admission to critical care

    Brazzelli, M., Aucott, L., Aceves Martins, M., Robertson, C., Jacobsen, E., Imamura, M., Poobalan, A., Manson, P., Scotland, G., Kaye, C., Sawhney, S., Boyers, D.
    National Institute for Health and Care Excellence (NICE). 376 pages
    Books and Reports: Commissioned Reports
  • TYRX Absorbable Antibacterial Envelope for preventing infection from cardiac implantable electronic devices.

    Hernández, R. A., Robertson, C., Scott, N., Scotland, G., Booth, C., Manson, P., Broadhurst, P., Brazzelli, M.
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports
  • Contrast-enhanced ultrasound and/or colour duplex ultrasound for surveillance after endovascular abdominal aortic aneurysm repair: a systematic review and economic evaluation

    Brazzelli, M., Hernández, R., Sharma, P., Robertson, C., Shimonovich, M., MacLennan, G., Fraser, C., Jamieson, R., Vallabhaneni, S. R.
    Health Technology Assessment, vol. 22, no. 72, pp. 1-220
    Contributions to Journals: Articles
  • Child food insecurity in the UK: a rapid review

    Aceves Martins, M., Cruickshank, M., Fraser, C., Brazzelli, M. G.
    Public Health Research, vol. 6, no. 13
    Contributions to Journals: Articles
  • COMPARISON OF NINE SURGICAL TREATMENTS FOR WOMEN WITH STRESS URINARY INCONTINENCE: A COST-EFFECTIVENESS AND VALUE OF INFORMATION ANALYSIS

    Javanbakht, M., Moloney, E., Brazzelli, M., Wallace, S. A., Ternent, L., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Imamura, M., Hudson, J., Shimonovich, M., MacLennan, G., Vale, L., Craig, D.
    11th Annual European UroGynaecological Association Congress
    Contributions to Conferences: Abstracts
  • Dupilumab for treating adults with moderate to severe atopic dermatitis.

    Hernández, R. A., Cruickshank, M., Dimitrova, M. P., Cooper, D. J., Aucott, L. S., Fraser, C., Shimonovich, M., Ormerod, A., Scotland, G. S., Brazzelli, M. G.
    Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence
    Books and Reports: Commissioned Reports
  • EMA and NICE Appraisal Processes for Cancer Drugs: Current Status and Uncertainties

    Dickson, R., Boland, A., Duarte, R., Kotas, E., Woolacott, N., Hodgson, R., Riemsma, R., Grimm, S., Ramaekers, B., Joore, M., Büyükkaramikli, N., Kaltenthaler, E., Stevenson, M., Pandor, A., Edwards, S., Hoyle, M., Shepherd, J., Armoiry, X., Brazzelli, M.
    Applied Health Economics and Health Policy, vol. 16, no. 4, pp. 429-432
    Contributions to Journals: Articles
  • Multiple-frequency bioimpedance devices for fluid management in people with chronic kidney disease receiving dialysis: a systematic review and economic evaluation

    Scotland, G., Cruickshank, M., Jacobsen, E., Cooper, D., Fraser, C., Shimonovich, M., Marks, A., Brazzelli, M.
    Health Technology Assessment, vol. 22, no. 1, pp. 1-138
    Contributions to Journals: Literature Reviews
  • Abiraterone for treating newly diagnosed metastatic hormone-naïve prostate cancer.

    Cummins, E., Aucott, L. S., Robertson, C., Fraser, C., Johnston, R., Lam, T., Brazzelli, M. G.
    Commissioned by National Institute for Health and Care Excellence (NICE). Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence
    Books and Reports: Commissioned Reports
  • Teduglutide for treating short bowel syndrome

    Scotland, G., Kopasker, D., Scott, N., Cruickshank, M., Hernández, R. A., Fraser, C. M., McLean, M., McKinlay, A., Brazzelli, M.
    Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 142 pages
    Books and Reports: Commissioned Reports
  • Doppler ultrasound, CT angiography, MR angiography, and contrast-enhanced MR angiography versus intra-arterial angiography for moderate and severe carotid stenosis in symptomatic patients

    Chappell, F. M., Wardlaw, J. M., Brazzelli, M., Best, J. J.
    Cochrane Database of Systematic Reviews, vol. 2017, no. 2, CD007423
    Contributions to Journals: Articles
  • Aflibercept for treating myopic choroidal neovascularisation

    Brazzelli, M. G., Cummins, E., Fielding, S. A., Cruickshank, M., Fraser, C. M., Azuara-Blanco, A.
    Commissioned by Department of Health via the NIHR HTA Programme. NICE Fast Track Appraisal Programme. London: National Institute for Health and Care Excellence. 252 pages
    Books and Reports: Commissioned Reports
  • The eEffectiveness and cost-effectiveness of Surgical Treatments for womEn with stRess urinary incontinence:: an evidence synthesis (ESTER)

    Brazzelli, M., Craig, D., Imamura, M., Wallace, S., MacLennan, G., Hudson, J., Saraswat, L., Omar, M. I., Montgomery, I.
    Contributions to Journals: Registered Reports
  • Physical Fitness Training for Patients with Stroke

    Saunders, D. H., Sanderson, M., Hayes, S., Kilrane, M., Greig, C. A., Brazzelli, M., Mead, G. E.
    Stroke, vol. 47, no. 9, pp. e219-e220
    Contributions to Journals: Articles
  • A randomised controlled trial comparing laparoscopic cholecystectomy with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated symptomatic gallstones. (C-Gall trial)

    Malik, M., Murchie, P., Gillies, K., Brazzelli, M. G., Avenell, A., Hernandez, R., Norrie, J., Blazeby, J., Ramsay, C., Ahmed, I.
    International Surgical Congress of the Association-of-Surgeons-of-Great-Britain-and-Ireland, pp. 195-196
    Contributions to Journals: Abstracts
  • Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review

    Cruickshank, M., Henderson, L., MacLennan, G., Fraser, C., Campbell, M., Blackwood, B., Gordon, A., Brazzelli, M.
    Health Technology Assessment, vol. 20, no. 25, pp. 0-120
    Contributions to Journals: Literature Reviews
  • Author Response - ABCD2 score and secondary stroke prevention: Meta-analysis and effect per 1,000 patients triaged

    Wardlaw, J. M., Brazzelli, M., Chappell, F., Dennis, M. S., Sandercock, P. A.
    Neurology, vol. 86, no. 7, pp. 697
    Contributions to Journals: Letters
  • Physical fitness training for stroke patients

    Sanders, D. H., Sanderson, M., Hayes, S., Kilrane, M., Greig, C. A., Brazzelli, M., Mead, G. E.
    Cochrane Database of Systematic Reviews, no. 3, pp. 1-411
    Contributions to Journals: Literature Reviews
  • The clinical and cost-effectiveness of open mesh repairs in adults presenting with a clinically diagnosed unilateral, primary inguinal hernia who are operated in an elective setting: systematic review and economic evaluation

    Sharma, P., Boyers, D., Scott, N. W., Hernandez, R. A., Fraser, C. M., Cruickshank, M., Ahmed, I., Ramsay, C. R., Brazzelli, M. G.
    Health Technology Assessment, vol. 19, no. 92, pp. i - 141
    Contributions to Journals: Literature Reviews
  • Collagenase clostridium histolyticum for the treatment of Dupuytren’s contracture: systematic review and economic evaluation

    Brazzelli, M., Cruickshank, M., Tassie, E., McNamee, P., Robertson, C., Elders, A., Fraser, C., Hernandez, R., Lawrie, D., Ramsay, C.
    Health Technology Assessment, vol. 19, no. 90, pp. 1-202
    Contributions to Journals: Articles
  • ABCD2 score and secondary stroke prevention: Meta-analysis and effect per 1,000 patients triaged

    Wardlaw, J. M., Brazzelli, M., Chappell, F. M., Miranda, H., Shuler, K., Sandercock, P. A. G., Dennis, M. S.
    Neurology, vol. 85, no. 4, pp. 373-380
    Contributions to Journals: Articles
  • Ablative therapy for people with localised prostate cancer: a systematic review and economic evaluation

    Ramsay, C. R., Adewuyi, T. E., Gray, J., Hislop, J., Shirley, M. D., Jayakody, S., MacLennan, G., Fraser, C., MacLennan, S., Brazzelli, M., N'Dow, J., Pickard, R., Robertson, C., Rothnie, K., Rushton, S. P., Vale, L., Lam, T. B.
    Health Technology Assessment, vol. 19, no. 49, pp. 1-524
    Contributions to Journals: Articles
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