People

Professor Miriam Brazzelli

Professor Miriam Brazzelli
Professor Miriam Brazzelli
Professor Miriam Brazzelli

Personal Chair

About
Email Address
m.brazzelli@abdn.ac.uk
Telephone Number
+44 (0)1224 438404
Office Address
Floor 2 Room 204 Health Sciences Building
Foresterhill Campus
Foresterhill
AB25 2ZD

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School/Department
School of Medicine, Medical Sciences and Nutrition
ORCiD

Biography

Miriam Brazzelli obtained her degree in Physiotherapy from the San Carlo Borromeo Physiotherapy School in 1988, followed by an Honours degree in Psychology (Cognitive Psychology) from the University of Turin, Italy, in 1997. She began her career with appointments in the field of physiotherapy and neuropsychology. In January 1999, she joined the Unit, and in 2005 was awarded a Research Fellowship by the Chief Scientist Office of the Scottish Executive Health Department, which focused on methods for conducting systematic reviews of diagnostic test accuracy studies. She earned her PhD in Public Health Sciences from the University of Edinburgh in 2011. She re-joined the Unit in February 2012 as the lead of the Knowledge Synthesis Programme within the wider Healthcare Assessment Programme. Her research focuses on complex evidence syntheses and health technology assessments, with the aim of evaluating the clinical and cost-effectiveness of both new and existing healthcare, social care and public health interventions.

Qualifications

  • Degree Physiotherapy 
    1988 - Physiotherapy School, Azienda Ospedaliera San Carlo Borromeo, Milan, Italy 
  • BSc, Hons Psychology 
    1997 - University of Turin, Italy 
  • PhD by Research, Public Health Sciences 
    2011 - University of Edinburgh 

Memberships and Affiliations

Internal Memberships

Member of the ACE Public Engagement Group.

Member of the Institute of Applied Health Sciences (IAHS) Equality, Diversity and Inclusion Group.

External Memberships

Member of the NIHR HTA Commissioning Funding Committee (since May 2023)

Latest Publications

  • Duration of wound coverage for the prevention of surgical site infections after surgery: A systematic review of current evidence with meta-analysis of randomised controlled trials

    Cruickshank, M., Brazzelli, M., Loudon, K., Ramsay, G.
    International Wound Journal
    Contributions to Journals: Articles

  • Concordance between automated/semi-automated measurement and manual assessment of mammographic breast density in individuals undergoing breast cancer screening: A systematic review

    Robertson, C., Cooper, D., Duggan, S. N., Manson, P., Imamura, M., Hernández, R. A., Clarke, M., Treweek, S., Brazzelli, M.
    Journal of Medical Screening
    Contributions to Journals: Articles

  • Trial informativeness across research practices: Initial findings from a mapping exercise

    Prowse, S., Brazzelli, M., Bain, J., Treweek, S.
    Journal of Clinical Epidemiology, 112274
    Contributions to Journals: Articles

  • DECODE: An innovative tool to aid cross-linguistic neuropsychological assessment

    Calia, C., Della Sala, S., O’Donald, F., Forrest, M., Brazzelli, M.
    Clinical Neuropsychologist
    Contributions to Journals: Articles

  • Clinical utility of biomarkers for outcomes prediction in adults with suspected sepsis presenting to the emergency department: a synthesis of current evidence

    Imamura, M., Duggan, S. N., Vadiveloo, T., Cooper, J. G., Kaye, C. T., Manson, P., Virgili, G., Aucott, L., Clarke, M., Brazzelli, M.
    Health Technology Assessment, pp. 1-90
    Contributions to Journals: Articles

View My Publications

Research

Research Overview

My research focuses on complex evidence syntheses and health technology assessments (HTAs), aimed at evaluating the clinical and cost-effectiveness of both new and established healthcare interventions. I have expertise in conducting various types of systematic reviews - including quantitative, qualitative, and mixed-methods reviews - across a wide range of topics in healthcare, public health, and social care. This includes work on interventions targeting specific clinical conditions, as well as broader evaluations and policy-relevant evidence syntheses. My work supports evidence-informed decision-making by synthesising diverse forms of evidence to address complex questions in real-world settings.

Research Areas

Applied Health Sciences

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Research Specialisms

  • Health Sciences
  • Applied Science
  • Neuroscience

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Collaborations

ABEC, the Aberdeen Belfast Collaboration, is a collaborative initiative between the University of Aberdeen and Queen's University Belfast

Teaching

Teaching Responsibilities

Contributing to the PU5526 Systematic Reviewing course by delivering lectures and marking students' assignments.

Publications

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  • Laparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones: the C-GALL RCT

    Innes, K., Ahmed, I., Hudson, J., Hernández, R. A., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J. M., Brazzelli, M., Cotton, S., Croal, B., Forrest, M., MacLennan, G., Murchie, P., Wileman, S., Ramsay, C.
    Health Technology Assessment, vol. 28, no. 26, pp. 1-151
    Contributions to Journals: Articles

  • What factors influence the uptake of bowel, breast, and cervical cancer screening?: An overview of international research

    Prowse, S., Brazzelli, M., Treweek, S.
    European Journal of Public Health, vol. 34, no. 4, pp. 818–825
    Contributions to Journals: Articles

  • Fruquintinib for previously treated metastatic colorectal cancer [ID6274]: NICE Single Technology Appraisal

    Boyers, D., Booth, C., Cruickshank, M., Kilonzo, M., Cooper, D., Manson, P., Braun, M., Brazzelli, M.
    Commissioned by National Institute for Health and Care Excellence (NICE). Aberdeen HTA Group
    Books and Reports: Commissioned Reports

  • Reversal of stoma with biosynthetic mesh fascial reinforcement: a systematic review and meta-analysis

    Dewantoro, D., Manson, P., Brazzelli, M., Ramsay, G.
    Colorectal Disease, vol. 26, no. 4, pp. 632-642
    Contributions to Journals: Articles

  • Using the GRADE Evidence to Decision Framework to reach recommendations together with ethnic minority community organisations: the example of COVID-19 vaccine uptake in the UK

    Treweek, S., Brazzelli, M., Crosse, A., Daga, S., Isaacs, T., Sunga, R., Collaboration for Change
    Journal of Clinical Epidemiology, vol. 168, 111268
    Contributions to Journals: Articles

  • What is the impact of long-term COVID-19 on workers in healthcare settings? A rapid systematic review of current evidence

    Cruickshank, M., Brazzelli, M., Manson, P., Torrance, N., Grant, A.
    PloS ONE, vol. 19, no. 3 , e0299743
    Contributions to Journals: Review articles

  • Cost-effectiveness of testosterone treatment utilising individual patient data from randomised controlled trials in men with low testosterone levels

    Hernández, R., de Silva, N. L., Hudson, J., Cruickshank, M., Quinton, R., Manson, P., Dhillo, W. S., Bhattacharya, S., Brazzelli, M., Jayasena, C. N.
    Andrology, vol. 12, no. 3, pp. 477-486
    Contributions to Journals: Articles

  • The experience of poor sleep in people with fibromyalgia: a qualitative meta-synthesis

    Robertson, C., Beasley, M., Stevens, M., Imamura, M., Whibley, D., Aucott, L., Manson, P., Abhishek, A., Dulake, D., Macfarlane, G., Tang, N. K. Y., Brazzelli, M., Gillies, K.
    Sleep Medicine, vol. 115, no. Suppl 1, pp. 192
    Contributions to Journals: Abstracts

  • Ivosidenib for treating advanced cholangiocarcinoma with an IDH1 R132 mutation after 1 or more systemic treatments

    Imamura, M., Getaneh, A., Cooper, D., Cruickshank, M., Manson, P., Shaukat, A. A., Brazzelli, M., Scotland, G.
    National Institute for Health and Care Excellence (NICE). 20 pages
    Books and Reports: Commissioned Reports

  • Netarsudil-latanoprost for previously treated openangle glaucoma or ocular hypertension [ID1363]: NICE Single Technology Appraisal

    Boyers, D., Scott, N., Cruickshank, M., Azharuddin, M., Hernández, R. A., Ayansina, D., Manson, P., Virgili, G., Azuara-Blanco, A., Brazzelli, M.
    Commissioned by National Institute for Health and Care Excellence (NICE). Aberdeen HTA Group
    Books and Reports: Commissioned Reports

  • Effectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial

    Ahmed, I., Hudson, J., Innes, K., Hernández, R., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J., Brazzelli, M., Cotton, S., Croal, B., Forrest, M., MacLennan, G., Murchie, P., Wileman, S., Ramsay, C.
    BMJ, vol. 383, e075383
    Contributions to Journals: Articles

  • Clinical Predictors Of Symptomatic Benefit In Men With Low Testosterone During Testosterone Treatment Compared With Placebo:: Results Of Individual Patient And Aggregate Data Meta-analyses

    Hudson, J., Cruickshank, M., Quinton, R., Aucott, L., Wu, F. C. W., Grossmann, M., Bhasin, S., Snyder, P., Ellenberg, S., Travison, T., Brock, G., Gianatti, E. J., Van Der Schouw, Y. T., Ramachandran, S., Svartberg, J., Hildreth, K., Antonic, K. G., Tenover, J. S., Tan, H. M., Ho Chee Kong, C., Shen Tan, W., Marks, L. S., Ross, R. J. M., Schwartz, R., Roberts, S., Andersen, M., Magnussen, L., Aceves Martins, M., Bhattacharya, S., Dhillo, W. S., Brazzelli, M., Jayasena, C. N.
    Annual Meeting of the Endocrine Society 2023, bvad114.1704
    Contributions to Journals: Abstracts

  • Elranatamab for treating relapsed or refractory multiple myeloma after 3 therapies [ID4026]: NICE Single Technology Appraisal

    Robertson, C., Kennedy, C., Vadiveloo, T., Aucott, L., Manson, P., Kilonzo, M., Brazzelli, M., Preston, G., Scotland, G.
    Commissioned by National Institute for Health and Care Excellence (NICE). Aberdeen HTA Group
    Books and Reports: Commissioned Reports

  • Symptomatic benefits of testosterone treatment in patient subgroups: a systematic review, individual participant data meta-analysis, and aggregate data meta-analysis

    Hudson, J., Cruickshank, M., Quinton, R., Aucott, L., Wu, F., Grossmann, M., Bhasin, S., Snyder, P. J., Ellenberg, S. S., Travison, T. G., Brock, G. B., Gianatti, E. J., van der Schouw, Y. T., Emmelot-Vonk, M. H., Giltay, E. J., Hackett, G., Ramachandran, S., Svartberg, J., Hildreth, K. L., Antonic, K. G., Tenover, J. L., Tan, H. M., Ho Chee Kong, C., Tan, W. S., Marks, L. S., Ross, R. J., Schwartz, R. S., Manson, P., Roberts, S. A., Skovsager Andersen, M., Velling Magnussen, L., Aceves-Martins, M., Gillies, K., Hernández, R., Oliver, N., Dhillo, W. S., Bhattacharya, S., Brazzelli, M., Jayasena, C. N.
    The Lancet Healthy Longevity, vol. 4, no. 10, pp. e561-e572
    Contributions to Journals: Articles

  • Deucravacitinib for treating moderate-to-severe plaque psoriasis

    Cruickshank, M., Cooper, D., Crozier, A., Robertson, C., Aucott, L., Manson, P., Ormerod, A., Scotland, G., Brazzelli, M.
    Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 155 pages
    Books and Reports: Commissioned Reports

  • Determinants and factors associated with infant food insecurity in high-income countries: A scoping review

    Singal, K., Douglas, F. C. G., Paranjothy, S., Brazzelli, M.
    OSF.
    Other Contributions: Other Contributions

  • Secukinumab for Moderate-to-Severe Hidradenitis Suppurativa [ID4039]: NICE Single Technology Appraisal

    Scott, N., Kumar, S., Tsehaye, M., Imamura, M., Cruickshank, M., Manson, P., Ormerod, A., Brazzelli, M., Boyers, D.
    Commissioned by National Institute for Health and Care Excellence (NICE). Aberdeen HTA Group
    Books and Reports: Commissioned Reports

  • Short-Term Memory Conjunctive Binding in Alzheimer’s Disease: A Systematic Review and Meta-Analysis

    Cecchini, M. A., Parra, M. A., Brazzelli, M., Logie, R. H., Sala, S. D.
    Neuropsychology, vol. 37, no. 7, pp. 769–789
    Contributions to Journals: Articles

  • PMON260 Cost-Effectiveness of Testosterone Treatment for Men with Hypogonadism

    Jayasena, C. N., Hudson, J., Cruickshank, M., Kennedy, C., Quinton, R., Aceves Martins, M., Gillies, K., Manson, P., Dhillo, W. S., Bhattacharya, S., Brazzelli, M., Hernández, R. A.
    Annual Meeting of the Endocrine Society 2022
    Contributions to Conferences: Posters

  • PMON258 Patient-Reported Outcomes for men with Hypogonadism and the Impact of Low Testosterone Levels: a review of measures

    Jayasena, C. N., Aceves Martins, M., Quinton, R., Brazzelli, M., Aucott, L., Cruickshank, M., Manson, P., Hudson, J., Oliver, N., Hernández, R. A., Wu, F. C. W., Bhattacharya, S., Dhillo, W. S., Gilles, K.
    Annual Meeting of the Endocrine Society 2022
    Contributions to Conferences: Posters

  • Mesh fixation techniques for inguinal hernia repair: an overview of systematic reviews of randomised controlled trials

    Alabi, A., Haladu, N., Scott, N., Imamura, M., Ahmed, I., Ramsay, G., Brazzelli, M.
    Hernia, vol. 26, pp. 973–987
    Contributions to Journals: Articles

  • Management of the first stage of convulsive status epilepticus in adults: a systematic review of current randomised evidence

    Cruickshank, M., Imamura, M., Counsell, C., Aucott, L., Manson, P., Booth, C., Scotland, G., Brazzelli, M.
    Journal of Neurology, vol. 269, no. 7, pp. 3420-3429
    Contributions to Journals: Review articles

  • Open versus laparoscopic repair of inguinal hernia: an overview of systematic reviews of randomised controlled trials

    Haladu, N., Alabi, A., Brazzelli, M., Imamura, M., Ahmed, I., Ramsay, G., Scott, N. W.
    Surgical Endoscopy, vol. 36, pp. 4685–4700
    Contributions to Journals: Articles

  • Axicabtagene ciloleucel for treating relapsed or refractory diffuse large B-cell lymphoma after one systemic therapy

    Boyers, D., Cruickshank, M., Scott, N., Jacobsen, E., Kumar, S., Imamura, M., Manson, P., Preston, G., Brazzelli, M.
    London: Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 128 pages
    Books and Reports: Commissioned Reports

  • Adverse cardiovascular events and mortality in men during testosterone treatment: an individual patient and aggregate data meta-analysis

    Hudson, J., Cruickshank, M., Quinton, R., Aucott, L., Aceves Martins, M., Gillies, K., Bhasin, S., Snyder, P., Ellenberg, S., Grossmann, M., Travison, T., Gianatti, E., van der Schouw, Y., Emmelot Vonk, M., Gilaty, E., Hackett, G., Ramchandran, S., Svartberg, J., Hildreth, K., Groti Antoniv, K., Brock, G., Tenover, L., Meng, H., Ho Chee Kong, C., Shen Tan, W., Mark, L., Ross, R., Schwartz, R., Manson, P., Roberts, S., Skicsage Andersen, M., Velling, L., Hernández, R. A., Oliver, N., Wu, F. C. W., Dhillo, W. S., Bhattacharya, S., Brazzelli, M., Jayasena, C. N.
    The Lancet Healthy Longevity, vol. 3, no. 6, pp. e381–393
    Contributions to Journals: Articles
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