Personal Chair
- About
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- Email Address
- m.brazzelli@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438404
- Office Address
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Miriam Brazzelli obtained her degree in Physiotherapy from the San Carlo Borromeo Physiotherapy School in 1988, followed by an Honours degree in Psychology (Cognitive Psychology) from the University of Turin, Italy, in 1997. She began her career with appointments in the field of physiotherapy and neuropsychology. In January 1999, she joined the Unit, and in 2005 was awarded a Research Fellowship by the Chief Scientist Office of the Scottish Executive Health Department, which focused on methods for conducting systematic reviews of diagnostic test accuracy studies. She earned her PhD in Public Health Sciences from the University of Edinburgh in 2011. She re-joined the Unit in February 2012 as the lead of the Knowledge Synthesis Programme within the wider Healthcare Assessment Programme. Her research focuses on complex evidence syntheses and health technology assessments, with the aim of evaluating the clinical and cost-effectiveness of both new and existing healthcare, social care and public health interventions.
Qualifications
- Degree Physiotherapy1988 - Physiotherapy School, Azienda Ospedaliera San Carlo Borromeo, Milan, Italy
- BSc, Hons Psychology1997 - University of Turin, Italy
- PhD by Research, Public Health Sciences2011 - University of Edinburgh
Memberships and Affiliations
- Internal Memberships
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Member of the ACE Public Engagement Group.
Member of the Institute of Applied Health Sciences (IAHS) Equality, Diversity and Inclusion Group.
- External Memberships
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Member of the NIHR HTA Commissioning Funding Committee (since May 2023)
Latest Publications
Supplemental imaging modalities for breast cancer screening in women with dense breasts: A systematic review with economic considerations
Breast, vol. 85, 104668Contributions to Journals: ArticlesTrifluridine-tipiracil with bevacizumab for treating metastatic colorectal cancer after 2 systemic treatments [ID6298]: NICE Single Technology Appraisal
Commissioned by National Institute for Health and Care Excellence (NICE). Aberdeen HTA GroupBooks and Reports: Commissioned ReportsEffects of Pharmacologic and Nonpharmacologic Interventions for the Management of Sleep Problems in People With Fibromyalgia: Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Arthritis Care & Research, vol. 77, no. 9, pp. 1095-1105Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1002/acr.25505
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/c3336c40-e1b2-42d1-92ee-088c3b63004f/download
Tackling health inequalities in cancer screening: Experiences of Eastern European and African communities in Northeast Scotland
Cancer Medicine, vol. 14, no. 18, e71236Contributions to Journals: ArticlesWhat are the influences on women’s preferences and decision-making when planning mode of birth in high-income countries? A qualitative systematic review
AJOG Global Reports, 100556Contributions to Journals: Articles
- Research
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Research Overview
My research focuses on complex evidence syntheses and health technology assessments (HTAs), aimed at evaluating the clinical and cost-effectiveness of both new and established healthcare interventions. I have expertise in conducting various types of systematic reviews - including quantitative, qualitative, and mixed-methods reviews - across a wide range of topics in healthcare, public health, and social care. This includes work on interventions targeting specific clinical conditions, as well as broader evaluations and policy-relevant evidence syntheses. My work supports evidence-informed decision-making by synthesising diverse forms of evidence to address complex questions in real-world settings.
Research Areas
Applied Health Sciences
Research Specialisms
- Health Sciences
- Applied Science
- Neuroscience
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
Collaborations
ABEC, the Aberdeen Belfast Collaboration, is a collaborative initiative between the University of Aberdeen and Queen's University Belfast
- Teaching
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Teaching Responsibilities
Contributing to the PU5526 Systematic Reviewing course by delivering lectures and marking students' assignments.
- Publications
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Netarsudil-latanoprost for previously treated openangle glaucoma or ocular hypertension [ID1363]: NICE Single Technology Appraisal
Commissioned by National Institute for Health and Care Excellence (NICE). Aberdeen HTA GroupBooks and Reports: Commissioned ReportsEffectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial
BMJ, vol. 383, e075383Contributions to Journals: ArticlesClinical Predictors Of Symptomatic Benefit In Men With Low Testosterone During Testosterone Treatment Compared With Placebo:: Results Of Individual Patient And Aggregate Data Meta-analyses
Annual Meeting of the Endocrine Society 2023, bvad114.1704Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1210/jendso/bvad114.1704
Elranatamab for treating relapsed or refractory multiple myeloma after 3 therapies [ID4026]: NICE Single Technology Appraisal
Commissioned by National Institute for Health and Care Excellence (NICE). Aberdeen HTA GroupBooks and Reports: Commissioned ReportsSymptomatic benefits of testosterone treatment in patient subgroups: a systematic review, individual participant data meta-analysis, and aggregate data meta-analysis
The Lancet Healthy Longevity, vol. 4, no. 10, pp. e561-e572Contributions to Journals: ArticlesDeucravacitinib for treating moderate-to-severe plaque psoriasis
Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 155 pagesBooks and Reports: Commissioned ReportsDeterminants and factors associated with infant food insecurity in high-income countries: A scoping review
OSF.Other Contributions: Other Contributions- [ONLINE] DOI: https://doi.org/10.17605/OSF.IO/ZSPK8
Secukinumab for Moderate-to-Severe Hidradenitis Suppurativa [ID4039]: NICE Single Technology Appraisal
Commissioned by National Institute for Health and Care Excellence (NICE). Aberdeen HTA GroupBooks and Reports: Commissioned ReportsShort-Term Memory Conjunctive Binding in Alzheimer’s Disease: A Systematic Review and Meta-Analysis
Neuropsychology, vol. 37, no. 7, pp. 769–789Contributions to Journals: ArticlesPMON260 Cost-Effectiveness of Testosterone Treatment for Men with Hypogonadism
Annual Meeting of the Endocrine Society 2022Contributions to Conferences: Posters- [ONLINE] DOI: https://doi.org/10.1210/jendso/bvac150.1447
PMON258 Patient-Reported Outcomes for men with Hypogonadism and the Impact of Low Testosterone Levels: a review of measures
Annual Meeting of the Endocrine Society 2022Contributions to Conferences: Posters- [ONLINE] DOI: https://doi.org/10.1210/jendso/bvac150.1445
Mesh fixation techniques for inguinal hernia repair: an overview of systematic reviews of randomised controlled trials
Hernia, vol. 26, pp. 973–987Contributions to Journals: ArticlesManagement of the first stage of convulsive status epilepticus in adults: a systematic review of current randomised evidence
Journal of Neurology, vol. 269, no. 7, pp. 3420-3429Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1007/s00415-022-10979-2
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/37bb6e56-6464-46d4-9661-f1cacc32dc10/download
- [ONLINE] View publication in Scopus
Open versus laparoscopic repair of inguinal hernia: an overview of systematic reviews of randomised controlled trials
Surgical Endoscopy, vol. 36, pp. 4685–4700Contributions to Journals: ArticlesAxicabtagene ciloleucel for treating relapsed or refractory diffuse large B-cell lymphoma after one systemic therapy
London: Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 128 pagesBooks and Reports: Commissioned ReportsAdverse cardiovascular events and mortality in men during testosterone treatment: an individual patient and aggregate data meta-analysis
The Lancet Healthy Longevity, vol. 3, no. 6, pp. e381–393Contributions to Journals: ArticlesIdentifying the outcomes important to men with hypogonadism: a qualitative evidence synthesis
Journal of Andrology, vol. 10, no. 4, pp. 625-641Contributions to Journals: ArticlesAxicabtagene ciloleucel for treating relapsed or refractory low-grade non-Hodgkin lymphoma
London: Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 106 pagesBooks and Reports: Commissioned ReportsPre-hospital and emergency department treatment of convulsive status epilepticus in adults: an evidence synthesis
Health technology assessment (Winchester, England), vol. 26, no. 20, pp. 1-76Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/RSVK2062
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/0d0add37-106c-48d5-b491-224909bef442/download
- [ONLINE] View publication in Scopus
Biomarkers for assessing acute kidney injury for people who are being considered for admission to critical care: a systematic review and cost-effectiveness analysis
Health Technology Assessment, vol. 26, no. 7, pp. 1-286Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/UGEZ4120
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/26a1aa20-06d0-4c43-b8c9-0494cd42e46d/download
Relugolix with oestradiol and norethisterone acetate for treating uterine fibroids
Commissioned by National Institute for Health and Care Excellence. London: Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 171 pagesBooks and Reports: Commissioned ReportsCost-effectiveness and value of information analysis of NephroCheck and NGAL tests compared to standard care for the diagnosis of acute kidney injury
BMC Nephrology, vol. 22, 399Contributions to Journals: ArticlesDistance assessment of cognitive deficits in older immigrants
Alzheimer's and Dementia, vol. 17, no. S8, e049315Contributions to Journals: Special Issues- [ONLINE] DOI: https://doi.org/10.1002/alz.049315
- [ONLINE] View publication in Scopus
Teduglutide for treating short bowel syndrome
Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 123 pagesBooks and Reports: Commissioned ReportsQuadas-c: A tool for assessing risk of bias in comparative diagnostic accuracy studies
Annals of Internal Medicine, vol. 174, no. 11, pp. 1592-1599Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.7326/M21-2234
- [ONLINE] View publication in Scopus
- [ONLINE] https://eprints.whiterose.ac.uk/182770/