Search Menu
People

Dr Louie Van de Lagemaat

Dr Louie Van de Lagemaat
Dr Louie Van de Lagemaat
Dr Louie Van de Lagemaat

Bioinformatician

About
Office Address
G16 23 St. Machar Drive
Old Aberdeen Campus
23 St. Machar Drive
AB24 3RY

View on Map

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Louie van de Lagemaat joined the Centre for Genome-Enabled Biology and Medicine as a bioinformatician in October 2021. He completed his PhD in Genetics at the University of British Columbia, Canada in 2006. Subsequent positions focused on diverse subjects, including molecular neuroscience of the mammalian excitatory synapse and developmental and malignant haematopoiesis. He has used varied analytical methods such as linear and mixed effects models and has broad experience with short-read sequencing technologies including ChIP-seq, bulk and low-cell-count RNA-seq, mRNA splicing, ribosomal profiling (Ribo-seq), transcript methylation (meRIP-seq), poly-A tail length (tail-seq) and transcript half-life (SLAM-seq). He has also performed analysis of survival and loss of HLA allele heterozygosity in cancers.

Research

Research Specialisms

  • Genomics
  • Behavioural Biology
  • Bioinformatics

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.

Publications

Page 2 of 4 Results 11 to 20 of 35

  • Standardized experiments in mutant mice reveal behavioural similarity on 129S5 and C57BL/6J backgrounds

    van de Lagemaat, L. N., Stanford, L. E., Pettit, C. M., Strathdee, D. J., Strathdee, K. E., Elsegood, K. A., Fricker, D. G., Croning, M. D. R., Komiyama, N. H., Grant, S. G. N.
    Genes, Brain, and Behavior, vol. 16, no. 4, pp. 409-418
    Contributions to Journals: Articles

  • Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions

    Guitart, A. V., Panagopoulou, T. I., Villacreces, A., Vukovic, M., Sepulveda, C., Allen, L., Carter, R. N., van de Lagemaat, L. N., Morgan, M., Giles, P., Sas, Z., Gonzalez, M. V., Lawson, H., Paris, J., Edwards-Hicks, J., Schaak, K., Subramani, C., Gezer, D., Armesilla-Diaz, A., Wills, J., Easterbrook, A., Coman, D., So, C. W. E., O'Carroll, D., Vernimmen, D., Rodrigues, N. P., Pollard, P. J., Morton, N. M., Finch, A., Kranc, K. R.
    Journal of Experimental Medicine, vol. 214, no. 3, pp. 719-735
    Contributions to Journals: Articles

  • Psychometric precision in phenotype definition is a useful step in molecular genetic investigation of psychiatric disorders

    Xu, M. K., Gaysina, D., Barnett, J. H., Scoriels, L., van de Lagemaat, L. N., Wong, A., Richards, M., Croudace, T. J., Jones, P. B., LHA Genetics Group
    Translational Psychiatry, vol. 5, no. 6, pp. e593
    Contributions to Journals: Articles

  • Age-related decreased inhibitory vs. excitatory gene expression in the adult autistic brain.

    van de Lagemaat, L., Nijhof, B., Bosch, D., Kohansal-Nodehi, M., Shivakumar, K., Heimel, J.
    Frontiers in Neuroscience, vol. 8
    Contributions to Journals: Articles

  • Human post-mortem synapse proteome integrity screening for proteomic studies of postsynaptic complexes

    Bayés, ?., Collins, M. O., Galtrey, C. M., Simonnet, C., Roy, M., Croning, M. D. R., Gou, G., van de Lagemaat, L. N., Milward, D., Whittle, I. R., Smith, C., Choudhary, J. S., Grant, S. G. N.
    Molecular brain, vol. 7, 88
    Contributions to Journals: Articles

  • Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins

    Hill, W. D., Davies, G., Van De Lagemaat, L. N., Christoforou, A., Marioni, R. E., Fernandes, C. P. D., Liewald, D. C., Croning, M. D. R., Payton, A., Craig, L. C. A., Whalley, L. J., Horan, M., Ollier, W., Hansell, N. K., Wright, M. J., Martin, N. G., Montgomery, G. W., Steen, V. M., Le Hellard, S., Espeseth, T., Lundervold, A. J., Reinvang, I., Starr, J. M., Pendleton, N., Grant, S. G. N., Bates, T. C., Deary, I. J.
    Translational Psychiatry, vol. 4, pp. 1-8
    Contributions to Journals: Articles

  • Synaptic scaffold evolution generated components of vertebrate cognitive complexity

    Nithianantharajah, J., Komiyama, N. H., McKechanie, A., Johnstone, M., Blackwood, D. H., Clair, D. S., Emes, R. D., Van De Lagemaat, L. N., Saksida, L. M., Bussey, T. J., Grant, S. G.
    Nature Neuroscience, vol. 16, no. 1, pp. 16-24
    Contributions to Journals: Articles

  • Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins

    Bayés, A., Collins, M. O., Croning, M. D. R., van de Lagemaat, L. N., Choudhary, J. S., Grant, S. G. N.
    PloS ONE, vol. 7, no. 10, e46683
    Contributions to Journals: Articles

  • An anatomically comprehensive atlas of the adult human brain transcriptome.

    Hawrylycz, M., Lein, E., Guillozet-Bongaarts, A., Shen, E., Ng, L., Miller, J., van de Lagemaat, L., Smith, K., Ebbert, A., Riley, Z., Abajian, C., Beckmann, C. F., Bernard, A., Bertagnolli, D., Boe, A., Cartagena, P., Chakravarty, M., Chapin, M., Chong, J., Dalley, R., David, D. B., Dang, C., Datta, S., Dee, N., Dolbeare, T., Faber, V., Feng, D., Fowler, D., Goldy, J., Gregor, B., Haradon, Z., Haynor, D., Hohmann, J., Horvath, S., Howard, R., Jeromin, A., Jochim, J., Kinnunen, M., Lau, C., Lazarz, E., Lee, C., Lemon, T., Li, L., Li, Y., Morris, J., Overly, C., Parker, P., Parry, S., Reding, M., Royall, J., Schulkin, J.
    Nature, vol. 489, pp. 391-399
    Contributions to Journals: Articles

  • De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.

    Kirov, G., Pocklington, A., Holmans, P., Ivanov, D., Ikeda, M., Ruderfer, D. M., Moran, J., Chambert, K., Toncheva, D., Georgieva, L., Grozeva, D., Fjodorova, M., Wollerton, R., Rees, E., Nikolov, I., van de Lagemaat, L., Bayés, ?., Fernandez, E., Olason, P., Böttcher, Y., Komiyama, N., Collins, M. O., choudhary, j., Stefansson, K., Stefansson, H., Grant, S., Purcell, S., Sklar, P., O'Donovan, M. C., Owen, M.
    Molecular Psychiatry, vol. 17, pp. 142-153
    Contributions to Journals: Articles
Show 10 | 25 | 50 | 100 results per page

Refine

Contributions to Journals

Working Papers

Update