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Professor Graham Scotland

Professor Graham Scotland
Professor Graham Scotland
Professor Graham Scotland

Interim Director of HERU

About
Email Address
g.scotland@abdn.ac.uk
Telephone Number
+44 (0)1224 437181
School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Graham is a Professor and leads the Assessment of Technologies theme in HERU. He joined HERU in 2004 and held a joint appointment between HERU and the Health Services Research Unit (HSRU) from 2012 to 2022. His current research interests span both model- and trial-based economic evaluation, with particular emphasis on the use decision analytic modelling alongside randomised controlled trials to maximise their value for informing health care decision making. Graham graduated from the University of Edinburgh in 1998 with BSc (Hons) in pharmacology, and following this undertook an MSc in Health Services and Public Health Research at the University of Aberdeen. After completing his MSc he worked at the Dugald Baird Centre for Research in Women's Health, University of Aberdeen, where he undertook research into economic aspects of maternal healthcare delivery in developing countries. Since his appointment in HERU he has gained over 19 years’ experience working in the area of health technology assessment. Graham also has an in interest in how the broader measures of value can incorporated in health technology assessment, and in 2012 completed a part-time PhD on methods for incorporating broader measures of value into economic evaluation in the area of reproductive healthcare.

Publications

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  • Effectiveness and cost-effectiveness of a peer-delivered, relational, harm reduction intervention to improve mental health, quality of life, and related outcomes, for people experiencing homelessness and substance use problems: protocol for the ‘SHARPS’ cluster randomised controlled trial

    Parkes, T., Carver, H., Boyd, J., Cotton, S., Breeman, S., Cooper, D., Forrest, M., Foster, R., Hawthorn, J., Hunt, K., Kilonzo, M., Matheson, C., Maxwell, M., Mercer, S. W., Pauly, B., Scotland, G., Steele, W., Sumnall, H., Wallace, J., Macaulay, L., MacLennan, G.
    Trials
    Contributions to Journals: Articles

  • User Preferences for the Use of AI in the National Breast Screening Programme: A Discrete Choice Experiment

    Branson, C., Anderson, L., Newlands, R., Lip, G., Loria Rebolledo, L. E., Antunes, M., Scotland, G.
    Contributions to Conferences: Papers

  • Cost-effectiveness of fenofibrate versus standard care for reducing the progression of diabetic retinopathy: an economic evaluation based on data from the LENS trial

    Scotland, G., Tsehaye, M., Styles, C., Logue, J., Sammons, E., Zayed, M., Emberson, J., Wade, R., Wallendszus, K., Stevens, W., Cretney, R., Harding, S., Leese, G., Currie, G., Armitage, J., Preiss, D., LENS collaborative group
    Diabetic Medicine, vol. 42, no. 9, e70098
    Contributions to Journals: Articles

  • Fenofibrate and progression of retinopathy in adults with diabetes: the randomised placebo-controlled LENS trial

    Preiss, D., Scotland, G.
    Health Technology Assessment
    Contributions to Journals: Articles

  • Sotatercept for treating pulmonary arterial hypertension [ID6163]: NICE Single Technology Appraisal

    Robertson, C., Boyers, D., Vadiveloo, T., Cooper, D., Brewis, M., McCabe, C., Manson, P., Brazzelli, M., Scotland, G.
    Commissioned by National Institute for Health and Care Excellence (NICE). Aberdeen HTA Group
    Books and Reports: Commissioned Reports

  • Patients and health care professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: Qualitative Study of the CATHETER II Trial

    Tripathee, S., Abdel-Fattah, M., Johnson, D., Constable, L., Cotton, S., Cooper, D., MacLennan, G., Evans, S., Young, A. J., Dimitropoulos, K., Hashim, H., Kilonzo, M., Larcombe, J., Little, P., Murchie, P., Myint, P. K., N'Dow, J., Paterson, C., Powell, K., Scotland, G., Thiruchelvam, N., Norrie, J., Omar, M. I., MacLennan, S.
    BMJ Open, vol. 15, no. 4, e087206
    Contributions to Journals: Articles

  • CATHETER II: a randomised controlled trial comparing the clinical and cost effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long term catheters

    Abdel-Fattah, M., Omar, M. I., Johnson, D., Cooper, D., Constable, L., Tripathee, S., MacLennan, S., Dimitropoulos, K., Evans, S., Hashim, H., Kilonzo, M., Larcombe, J., Little, P., Murchie, P., Myint, P. K., N'Dow, J., Paterson, C., Powell, K., Scotland, G., Thiruchelvam, N., Young, A., Cotton, S., Norrie, J., MacLennan, G.
    BMJ Open, vol. 14, no. 12, e087203
    Contributions to Journals: Articles

  • Direct and indirect costs of paediatric asthma in the UK: a cost analysis

    Kennedy, C., Scotland, G., Cotton, S., Turner, S.
    Archives of Disease in Childhood, vol. 109, no. 9, pp. 724-729
    Contributions to Journals: Articles

  • Ivosidenib for treating advanced cholangiocarcinoma with an IDH1 R132 mutation after 1 or more systemic treatments

    Imamura, M., Getaneh, A., Cooper, D., Cruickshank, M., Manson, P., Shaukat, A. A., Brazzelli, M., Scotland, G.
    National Institute for Health and Care Excellence (NICE). 20 pages
    Books and Reports: Commissioned Reports

  • Elranatamab for treating relapsed or refractory multiple myeloma after 3 therapies [ID4026]: NICE Single Technology Appraisal

    Robertson, C., Kennedy, C., Vadiveloo, T., Aucott, L., Manson, P., Kilonzo, M., Brazzelli, M., Preston, G., Scotland, G.
    Commissioned by National Institute for Health and Care Excellence (NICE). Aberdeen HTA Group
    Books and Reports: Commissioned Reports

  • Deucravacitinib for treating moderate-to-severe plaque psoriasis

    Cruickshank, M., Cooper, D., Crozier, A., Robertson, C., Aucott, L., Manson, P., Ormerod, A., Scotland, G., Brazzelli, M.
    Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 155 pages
    Books and Reports: Commissioned Reports

  • Economic evaluation of Medically Assisted Reproduction: an educational overview of methods and applications for healthcare professionals

    Luyten, J., Connolly, M. P., Verbeke, E., Buhler, K., Scotland, G., Lispi, M., Revelli, A., Borget, I., Cedrin-Durnerinm, I., D’hooghe, T. M.
    Best Practice & Research Clinical Obstetrics & Gynaecology, vol. 85 , pp. 217-228
    Contributions to Journals: Articles

  • Randomised controlled trial comparing the clinical and cost-effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long-term catheters: study protocol for the CATHETER II study

    Abdel-fattah, M., Johnson, D., Constable, L., Thomas, R., Cotton, S., Tripathee, S., Cooper, D., Boran, S., Dimitropoulos, K., Evans, S., Granitsiotis, P., Hashim, H., Kilonzo, M., Larcombe, J., Little, P., MacLennan, S., Murchie, P., Myint, P., N’Dow, J., Norrie, J., Omar, M. I., Paterson, C., Scotland, G., Thiruchelvam, N., MacLennan, G.
    Trials, vol. 23, no. 1, 630
    Contributions to Journals: Articles

  • Early detection of neovascular age-related macular degeneration: an economic evaluation based on data from the EDNA study

    Hernández, R., Banister, K., Goulao, B., Cook, J., Sivaprasad, S., Hogg, R. E., Azuara-Blanco, A., Heimann, H., Dimitrova, M. P., Gale, R., Porteous, M., Ramsay, C., Chakravarthy, U., Scotland, G., Kennedy, C.
    British Journal of Ophthalmology, vol. 106, no. 12, pp. 1754-1761
    Contributions to Journals: Articles

  • Management of the first stage of convulsive status epilepticus in adults: a systematic review of current randomised evidence

    Cruickshank, M., Imamura, M., Counsell, C., Aucott, L., Manson, P., Booth, C., Scotland, G., Brazzelli, M.
    Journal of Neurology, vol. 269, no. 7, pp. 3420-3429
    Contributions to Journals: Review articles

  • Reducing asthma attacks in children using exhaled nitric oxide (RAACENO) as a biomarker to inform treatment strategy: a multicentre, parallel, randomised, controlled, phase 3 trial

    Turner, S., Cotton, S., Wood, J., Bell, V., Raja, E. A., Scott, N., Morgan, H., Lawrie, L., Emele, D., Kennedy, C., Scotland, G., Fielding, S., MacLennan, G., Norrie, J., Forrest, M., Gaillard, E. A., de Jongste, J. C., Pijnenburg, M. W., Thomas, M., Price, D.
    The Lancet. Respiratory medicine, vol. 10, no. 6, pp. 584-592
    Contributions to Journals: Articles

  • Treatment guided by fractional exhaled nitric oxide in addition to standard care in 6- to 15-year-olds with asthma: the RAACENO RCT

    Turner, S., Cotton, S., Wood, J., Bell, V., Raja, E. A., Scott, N., Morgan, H., Lawrie, L., Emele, D., Kennedy, C., Scotland, G., Fielding, S., MacLennan, G., Norrie, J., Forrest, M., Gaillard, E. A., de Jongeste, J., Pijnenburg, M. W., Thomas, M., Price, D.
    Efficacy and Mechanism Evaluation, vol. 9, no. 4
    Contributions to Journals: Articles

  • Transfer of thawed frozen embryo versus fresh embryo to improve the healthy baby rate in women undergoing IVF: the E-Freeze RCT

    Maheshwari, A., Bari, V., Bell, J. L., Bhattacharya, S., Bhide, P., Bowler, U., Brison, D., Child, T., Chong, H. Y., Cheong, Y., Cole, C., Coomarasamy, A., Cutting, R., Goodgame, F., Hardy, P., Hamoda, H., Juszczak, E., Khalaf, Y., King, A., Kurinczuk, J. J., Lavery, S., Lewis-Jones, C., Linsell, L., Macklon, N., Mathur, R., Murray, D., Pundir, J., Raine-Fenning, N., Rajkohwa, M., Robinson, L., Scotland, G., Stanbury, K., Troup, S.
    Health Technology Assessment, vol. 26, no. 25
    Contributions to Journals: Articles

  • Axicabtagene ciloleucel for treating relapsed or refractory low-grade non-Hodgkin lymphoma

    Vadiveloo, T., Scotland, G., Booth, C., Robertson, C., Cruickshank, M., Aucott, L., Kennedy, C., Manson, P., Preston, G., Brazzelli, M.
    London: Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 106 pages
    Books and Reports: Commissioned Reports

  • Elective freezing of embryos versus fresh embryo transfer in IVF: a multicentre randomized controlled trial in the UK (E-Freeze)

    Maheshwari, A., Bell, J. L., Bhide, P., Brison, D., Child, T., Chong, H. Y., Cheong, Y., Cole, C., Coomarasamy, A., Cutting, R., Hardy, P., Hamoda, H., Juszczak, E., Khalaf, Y., Kurinczuk, J. J., Lavery, S., Linsell, L., Macklon, N., Mathur, R., Pundir, J., Raine-Fenning, N., Rajkohwa, M., Scotland, G., Stanbury, K., Troup, S., Bhattacharya, S.
    Human reproduction (Oxford, England), vol. 37, no. 3, pp. 476-487
    Contributions to Journals: Articles

  • Pre-hospital and emergency department treatment of convulsive status epilepticus in adults: an evidence synthesis

    Cruickshank, M., Imamura, M., Booth, C., Aucott, L., Counsell, C., Manson, P., Scotland, G., Brazzelli, M.
    Health technology assessment (Winchester, England), vol. 26, no. 20, pp. 1-76
    Contributions to Journals: Articles

  • Biomarkers for assessing acute kidney injury for people who are being considered for admission to critical care: a systematic review and cost-effectiveness analysis

    Brazzelli, M., Aucott, L., Aceves Martins, M., Robertson, C., Jacobsen, E., Imamura, M., Poobalan, A., Manson, P., Scotland, G., Kaye, C., Sawhney, S., Boyers, D.
    Health Technology Assessment, vol. 26, no. 7, pp. 1-286
    Contributions to Journals: Articles

  • Non-invasive testing for early detection of neovascular macular degeneration in unaffected second eyes of older adults: EDNA diagnostic accuracy study

    Banister, K., Cook, J. A., Scotland, G., Azuara-Blanco, A., Goulao, B., Heimann, H., Hernández, R. A., Hogg, R. E., Kennedy, C., Sivaprasad, S., Ramsay, C., Chakravarthy, U., EDNA study group
    Health Technology Assessment, vol. 26, no. 8
    Contributions to Journals: Articles

  • Cost-effectiveness and value of information analysis of NephroCheck and NGAL tests compared to standard care for the diagnosis of acute kidney injury

    Jacobsen, E., Sawhney, S., Brazzelli, M., Aucott, L., Scotland, G., Aceves Martins, M., Robertson, C., Imamura, M., Poobalan, A., Manson, P., Kaye, C., Boyers, D.
    BMC Nephrology, vol. 22, 399
    Contributions to Journals: Articles

  • Diagnostic Accuracy of Monitoring Tests of Fellow Eyes in Patients with Unilateral Neovascular Age-Related Macular Degeneration: Early Detection of Neovascular Age-Related Macular Degeneration Study

    Sivaprasad, S., Banister, K., Azuro-Blanco, A., Goulao, B., Cook, J. A., Hogg, R., Scotland, G., Heimann, H., Lotery, A., Ghanchi, F., Gale, R., Menon, G., Downey, L., Hopkins, N., Scanlon, P., Burton, B., Ramsay, C., Chakravarthy, U.
    Ophthalmology, vol. 128, no. 12, pp. 1736-1747
    Contributions to Journals: Articles

  • Teduglutide for treating short bowel syndrome

    Kennedy, C., Robertson, C., Cruickshank, M., Ayansina, D., Manson, P., Moroni, F., Brazzelli, M., Scotland, G.
    Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 123 pages
    Books and Reports: Commissioned Reports

  • Assessing couples' preferences for fresh or frozen embryo transfer: a discrete choice experiment

    Abdulrahim, B., Scotland, G., Bhattacharya, S., Maheshwari, A.
    Human reproduction (Oxford, England), vol. 36, no. 11, pp. 2891-2903
    Contributions to Journals: Articles

  • Palforzia for treating peanut allergy

    Cruickshank, M., Boyers, D., Scott, N., Robertson, C., Manson, P., Lumsden, C., Scotland, G., Brazzelli, M.
    London: Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 125 pages
    Books and Reports: Commissioned Reports

  • Venetoclax with a hypomethylating agent or low dose cytarabine for untreated acute myeloid leukaemia unsuitable for intensive chemotherapy

    Cruickshank, M., Kennedy, C., Aucott, L., Booth, C., Imamura, M., Vadiveloo, T., Manson, P., Preston, G., Scotland, G., Brazzelli, M.
    London: National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports

  • Berotralstat for preventing acute attacks of hereditary angioedema

    Robertson, C., Booth, C., Ayansina, D., Hernández, R. A., Manson, P., Herriot, R., Brazzelli, M., Scotland, G.
    London: National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports

  • Cost-effectiveness and value of information analysis of multiple frequency bioimpedance devices for fluid management in people with chronic kidney disease having dialysis

    Jacobsen, E., Cruickshank, M., Cooper, D., Marks, A., Brazzelli, M., Scotland, G.
    Cost Effectiveness and Resource Allocation, vol. 19, 24
    Contributions to Journals: Articles

  • The Help for Hay Fever community pharmacy-based pilot randomised controlled trial for intermittent allergic rhinitis

    Smith, S., Porteous, T., Bond, C., Francis, J., Lee, A. J., Lowrie, R., Scotland, G., Sheikh, A., Thomas, M., Wyke, S., Smith, L.
    npj Primary Care Respiratory Medicine, vol. 30, pp. 23
    Contributions to Journals: Articles

  • Glyceryl trinitrate to reduce the need for manual removal of retained placenta following vaginal delivery: The GOT-IT RCT

    Denison, F. C., Carruthers, K. F., Hudson, J., McPherson, G., Scotland, G., Brook-Smith, S., Clarkson, C., Peace, M., Brewin, J., Chua, G. N., Hallowell, N., Norman, J. E., Lawton, J., Norrie, J.
    Health Technology Assessment, vol. 23, no. 70, pp. 1-72
    Contributions to Journals: Articles

  • Atezolizumab monotherapy for untreated advanced non-small-cell lung cancer

    Aucott, L., Robertson, C., Walker, A., Manson, P., Price, G., Scotland, G., Brazzelli, M.
    Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence
    Books and Reports: Commissioned Reports

  • Darolutamide with androgen deprivation therapy for treating non-metastatic hormone-relapsed prostate cancer

    Scotland, G., Kennedy, C., Imamura, M., Cooper, D., Robertson, C., Booth, C., Urquhart, G., Brazzelli, M.
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports

  • Enzalutamide with ADT for treating metastatic hormone-sensitive prostate cancer

    Kopasker, D., Robertson, C., Aucott, L., Vadiveloo, T., Imamura, M., Manson, P., Walker, A., Urquhart, G., Brazzelli, M., Scotland, G., Aberdeen HTA Group
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports

  • Nitroglycerin for treatment of retained placenta: A randomised, placebo-controlled, multicentre, double-blind trial in the UK

    Denison, F., Carruthers, K. F., Hudson, J., McPherson, G., Chua, G. N., Peace, M., Brewin, J., Hallowell, N., Scotland, G., Lawton, J., Norrie, J., Norman, J. E., GOT-IT investigator team
    PLoS Medicine, vol. 16, no. 12, 1003001
    Contributions to Journals: Articles

  • Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial

    Cooper, K., Breeman, S., Scott, N. W., Scotland, G., Clark, J., Hawe, J., Hawthorn, R., Phillips, K., MacLennan, G., Wileman, S., McCormack, K., Hernández, R. A., Norrie, J., Bhattacharya, S., HEALTH Study Group
    The Lancet, vol. 394, no. 10207, pp. 1425-1436
    Contributions to Journals: Articles

  • Laparoscopic supracervical hysterectomy compared with second-generation endometrial ablation for heavy menstrual bleeding: the HEALTH RCT

    Cooper, K., Breeman, S., Scott, N. W., Scotland, G. S., Hernández, R. A., Clark, T. J., Hawe, J., Hawthorn, R., Phillips, K., Wileman, S. M., McCormack, K., Norrie, J., Bhattacharya, S.
    Health Technology Assessment, vol. 23, no. 53, pp. 1-107
    Contributions to Journals: Articles

  • Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins

    Brittenden, J., Cooper, D., Dimitrova, M., Scotland, G., Cotton, S. C., Elders, A., MacLennan, G., Ramsay, C. R., Norrie, J., Burr, J. M., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., Tassie, E., Francis, J., Campbell, M. K.
    The New England Journal of Medicine, vol. 381, no. 10, pp. 912-922
    Contributions to Journals: Articles

  • Study protocol: E-freeze-freezing of embryos in assisted conception: A randomised controlled trial evaluating the clinical and cost effectiveness of a policy of freezing embryos followed by thawed frozen embryo transfer compared with a policy of fresh embryo transfer, in women undergoing in vitro fertilisation

    Maheshwari, A., Bhattacharya, S., Bowler, U., Brison, D., Child, T., Cole, C., Coomarasamy, A., Cutting, R., Harbottle, S., Hardy, P., Juszczak, E., Khalaf, Y., Kurinczuk, J. J., Lavery, S., Lewis-Jones, C., Macklon, N., Raine-Fenning, N. J., Rajkohwa, M., Scotland, G., Troup, S.
    Reproductive Health, vol. 16, 81
    Contributions to Journals: Articles

  • Lanadelumab for preventing recurrent attacks of hereditary angioedema.

    Robertson, C., Walker, A., Jacobsen, E., Aucott, L., Herriot, R., Scotland, G., Brazzelli, M.
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports

  • Lorlatinib for previously treated ALK-positive advanced non-small-cell lung cancer

    Robertson, C., Fielding, S., Walker, A., Kopasker, D., Vadiveloo, T., Manson, P., Price, G., Brazzelli, M., Scotland, G.
    Commissioned by National Institute for Health and Care Excellence. Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence
    Books and Reports: Commissioned Reports

  • Risankizumab for treating moderate to severe plaque psoriasis

    Imamura, M., Cooper, D., Hernández, R. A., Ormerod, A., Scotland, G., Brazzelli, M., Aberdeen HTA Group
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports

  • The ARCHITECT and Alinity urine NGAL assays, urine NephroCheck test, and urine and plasma NGAL tests to help assess the risk of acute kidney injury in people who are being considered for admission to critical care

    Brazzelli, M., Aucott, L., Aceves Martins, M., Robertson, C., Jacobsen, E., Imamura, M., Poobalan, A., Manson, P., Scotland, G., Kaye, C., Sawhney, S., Boyers, D.
    National Institute for Health and Care Excellence (NICE). 376 pages
    Books and Reports: Commissioned Reports

  • TYRX Absorbable Antibacterial Envelope for preventing infection from cardiac implantable electronic devices.

    Hernández, R. A., Robertson, C., Scott, N., Scotland, G., Booth, C., Manson, P., Broadhurst, P., Brazzelli, M.
    National Institute for Health and Care Excellence (NICE)
    Books and Reports: Commissioned Reports

  • Dupilumab for treating adults with moderate to severe atopic dermatitis.

    Hernández, R. A., Cruickshank, M., Dimitrova, M. P., Cooper, D. J., Aucott, L. S., Fraser, C., Shimonovich, M., Ormerod, A., Scotland, G. S., Brazzelli, M. G.
    Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence
    Books and Reports: Commissioned Reports

  • Multiple-frequency bioimpedance devices for fluid management in people with chronic kidney disease receiving dialysis: a systematic review and economic evaluation

    Scotland, G., Cruickshank, M., Jacobsen, E., Cooper, D., Fraser, C., Shimonovich, M., Marks, A., Brazzelli, M.
    Health Technology Assessment, vol. 22, no. 1, pp. 1-138
    Contributions to Journals: Literature Reviews

  • HEALTH: laparoscopic supracervical hysterectomy versus second-generation endometrial ablation for the treatment of heavy menstrual bleeding: study protocol for a randomised controlled trial

    Cooper, K., McCormack, K., Breeman, S., Wood, J., Scott, N. W., Clark, J., Hawe, J., Hawthorn, R., Phillips, K., Hyde, A., McDonald, A., Forrest, M., Wileman, S., Scotland, G., Norrie, J., Bhattacharya, S., HEALTH Study Group
    Trials, vol. 19, 63
    Contributions to Journals: Articles

  • Teduglutide for treating short bowel syndrome

    Scotland, G., Kopasker, D., Scott, N., Cruickshank, M., Hernández, R. A., Fraser, C. M., McLean, M., McKinlay, A., Brazzelli, M.
    Evidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence. 142 pages
    Books and Reports: Commissioned Reports
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