Professor Dana Dawson

Professor Dana Dawson
DM, FRCP, D.Phil, FESC
Chair in Cardiovascular Medicine
- About
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Polwarth Building School of Medicine and Dentistry University of Aberdeen Foresterhill Aberdeen AB25 2ZD
Biography
Professor Dawson qualified in medicine at University of Medicine “Grigore T. Popa”, Iasi, Romania. After completing her MRCP with the Royal College of Physicians in London she read for a D. Phil in Cardiovascular Medicine at Merton College, University of Oxford. She trained in Cardiovascular Medicine in Edinburgh, Oxford and London in the UK and at the University of Virginia, Charlottesville, in the USA. In 2010 she moved to the University of Aberdeen and Aberdeen Royal Infirmary where she currently is Professor of Cardiovascular Medicine and Consultant Cardiologist.
She made a significant contribution in advancing knowledge in acute stress induced (Takotsubo) cardiomyopathy, one of the main areas of research interest within the group. Several Takotsubo studies are ongoing and the Scottish Takotsubo Registry is accruing all incident and prevalent cases dating back to 2010.
There is keen interest in other topics such as diet and exercise based interventions to improve cardio-metabolic health in patients with type 2 diabetes, mechanistic trials exploring the cardiac substrate in patients with COPD who show clinical improvement whilst on betablocker therapy. There is a developing interest in cardio-oncology and in therapies for acute coronary syndromes.
The group is working together with MR physicists towards the unique development of fast field cycling magnetic resonance for cardiovascular disease (with Professor David Lurie's group).
Professor Dana Dawson leads the Cardiology and Cardiovascular Research Unit and together with her NHS Consultant Colleagues who have distinct Principal Investigator roles, they bring specific expertise to the group, creating a broad scope of activities.
The Cardiology and Cardiovascular Research Unit also has strong collaborative links with molecular nutritionists, diabetes/endocrinology and oncology clinical colleagues, sport physiologists, MR and PET physicists, synthetic molecular chemists and cardio-thoracic surgeons.
Memberships and Affiliations
- Internal Memberships
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Team members and close collaborators:
Dr. Alice Mezincescu – Clinical Lecturer (former BHF Clinical Research Fellow)
Dr. Hassan Abbas – BHF Clinical Research Fellow
Dr. James Ross - Lecturer in Cardiovascular Magnetic Resonance Physics
Dr. David Gamble - BHF Clinical Research Fellow
Dr. Hilal Khan - Clinical Research Fellow
Dr. Maheshi Gunasekara - Clinical Research Fellow
Dr. Chaitanya Pradeep Joshi - Clinical Research Fellow - Dental, Elphinstone Scholar
Ms Amelia Rudd, MSc - BHF AHP Clinical Research Fellow
Miss Lesley Cheyne - Cardiovascular Technician
Ms Janaki Srivanastan – Senior Research Sonographer
Dr. Lionel Broche – Lecturer in Fast Field Cycling MR Physics
Dr. Gareth Davies - Fast Field Cycling MR Physics Reseach Fellow
Dr. Caroline Scally – former BHF Clinical Research Fellow
Miss Nadine Godsman – former BHF non-clinical PhD student
Nursing staff:
RN Valerie Harries
RN Paula Henderson
Research Radiographers:
Ms Nicola Crouch (MRI)
Mr Mike Hendry (MRI)
Ms Laura Reid (MRI)
Mrs Denise Forrest (CT)
Ms Louise Lamley (CT)
- External Memberships
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She is a member of the British Cardiovascular Society, American Heart Association, Fellow of the European Society of Cardiology (ESC), chair-elect of the Myocardial Function Working Group (ESC) and a Committee member of the Takotsubo Syndrome Study Group.
Prizes and Awards
Most recent mentored scientific investigations shortlisted for prize awards include:
1. Janaki Srivanasan – winner of the British Society of Echocardiography Young Investigator Research Prize, October 2016
2. Caroline Scally – finalist at the Early Career award, Society of Cardiovascular Magnetic Resonance, Washington, January 2017
3. Caroline Scally – finalist at the Samuel A Levine Young Investigator Award of the American Heart Association, Anaheim, CA, November 2017
4. Nadine Godsman – winner of the Young Investigator’s prize of the British Pharmacological Society – Pharmacology, December 2017 – London, England
5. Caroline Scally - finalist at the Melvin Judkins Young Investigator Award of the American Heart Association, Chicago, IL, November 2018
6. Alice Mezincescu – finalist at the Early Career Award-Translational Sciences of the Society of Cardiovascular Magnetic Resonance, Seattle, February 2019
- Research
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Funding and Grants
RESEARCH GRANTS – current:
- Replacement of (ultrasound) echocardiography equipment for clinical research, BHF Infrastructure Grant IG/F/21/50010, D Dawson, 2022, £73,604
- Epigenetic Phase Variation of Periodontal Bacteria – a Mechanistic Contributor to Coronary Artery Disease, BHF Clinical Research Training Fellowship - FS/CRTF/22/24275, K Hijazi (PI) and D Dawson, £217,509, 2022-2025
- Epidemiology and predisposition of acute stress-induced (takotsubo) Cardiomyopathy - BHF Research Training Fellowship (FS/RTF/20/30009, for Ms Amelia Rudd): D Dawson (CI), David Newby, 2021-2023, £215,051
- Demographic, multi-morbidity and genetic impact on myocardial involvement and its recovery from Covid-19: The Covid-Heart Study, NIHR, CI John Greenwood, D Dawson co-applicant, £775,095
- The next leap in cardiac magnetic resonance imaging: cycling the field: D Dawson (CI), D Lurie, L Broche, J Ross, H Abbas: BHF New Horizons Grant no. NH/19/1/34595, 2020-2024, £277,722
- Towards Elucidating the Genetic Predisposition for Acute Stress-Induced (Takostubo) Cardiomyopathy: D Dawson (Chief Investigator), Z Miedzybrodzka, Chest Heart and Stroke Scotland, 2019-2021, £24,950
- PhysicaL Exercise and mental wellbeing rehabilitation for Acute StrEss-induced takotsubo cardiomyopathy: The PLEASE trial BHF Project Grant no. PG/18/35/33786; D Dawson (Chief Investigator), D.E. Newby, Marc Petrie, S Leslie, C.C. Lang, G Horgan, S Gray, C Williams, 2019-2022, £298,134
- Cardiac Energetics and Breast Cancer Treatment, Tenovus Scotland 01, D Dawson (Chief Investigator), R Sharma, 2019-2021, £19,595
- Resting Cardiac Energetics in Patients Undergoing Anthracycline Chemotherapy for Breast Cancer, Friends of Anchor, D Dawson (Chief Investigator), R Sharma, 2019-2021, £14,724
- Fast Field Cycling-Magnetic Resonance Imaging (FFC-MRI): A New Diagnostic that Reveals Acutely Inflamed Coronary Artery Plaques by Detecting Fat Dysfunction: D Dawson (Chief Investigator), D Lurie, L Broche, Justin Rochford and Hussein El-Shafei, Grampian NHS-Endowments, 2018-2020, £9,350
- A randomised, double-blind placebo controlled trial to test if a beneficial effect of beta-blockers on exacerbations of chronic obstructive pulmonary disease (COPD) is restricted to those patients with occult heart disease: D Dawson (Chief Investigator), G Devereux, C Lang, B Lipowrth, W MacNee, N Mills, S Fielding, R Chaudhuri, P Short: BHF Project Grant no. PG/17/64/33205, 2018-2022, £299,169
- Duration of dual anti-platelet therapy in acute coronary syndrome across Scotland. The DUAL-ACS2 trial: D Newby (Chief Investigator), N Mills, K Fox, D Dawson, J Irving, D McAllister, A Morris, J Norrie, M Petrie, C Berry, M McEntegart: British Heart Foundation Clinical Study no. CS/17/4/32960, 2017-2022, £630,845
- Muscle fat compartments and turnover as a determinant of insulin sensitivity: D Dawson (Chief Investigator), M Delibegovic, S Gray, S Philip, P Whitfield, F Thies, G Lobley, British Heart Foundation Project Grant no. PG/15/88/31780, £259,358, 2016-2020
- Publications
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Page 1 of 3 Results 1 to 50 of 122
Myocardial infarction risk is increased by periodontal pathobionts: a cross-sectional study
Scientific Reports, vol. 12, no. 1, 18608Contributions to Journals: ArticlesStructural and functional brain changes in acute Takotsubo Syndrome
JACC. Heart failureContributions to Journals: ArticlesManganese-Enhanced Magnetic Resonance Imaging in Takotsubo Syndrome
CirculationContributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1161/CIRCULATIONAHA.122.060375
Myocarditis Following SARS-CoV2 mRNA Vaccination Against COVID-19: Facts and Open Questions
Journal of the American College of Cardiology, vol. 80, no. 14, pp. 1363-1365Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jacc.2022.08.003
Renin-Angiotensin and Endothelin Systems in Patients post Takotsubo Cardiomyopathy
Journal of the American Heart Association, vol. 11, no. 14, e025989Contributions to Journals: ArticlesPsilocybin-induced takotsubo cardiomyopathy
BMJ Case Reports, vol. 15, no. 5, e245863Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bcr-2021-245863
- [ONLINE] View publication in Scopus
Use of the oral beta blocker bisoprolol to reduce the rate of exacerbation in people with chronic obstructive pulmonary disease (COPD): a randomised controlled trial. (BICS)
Trials, vol. 23, no. 1, 307Contributions to Journals: ArticlesTakotsubo Syndrome: Pathophysiology, Emerging Concepts, and Clinical Implications
Circulation, vol. 145, no. 13, pp. 1002-1019Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1161/CIRCULATIONAHA.121.055854
Pathophysiology of Takotsubo syndrome - a joint scientific statement from the Heart Failure Association Takotsubo Syndrome Study Group and Myocardial Function Working Group of the European Society of Cardiology - Part 1: overview and the central role for catecholamines and sympathetic nervous system
European Journal of Heart Failure, vol. 24, no. 2, pp. 257-273Contributions to Journals: ArticlesNovel case of takotsubo cardiomyopathy following COVID-19 vaccination
BMJ Case Reports, vol. 15, no. 1, e247291Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bcr-2021-247291
- [ONLINE] View publication in Scopus
Serum antibody response against periodontal bacteria and risk of coronary heart disease: systematic review and meta-analysis
Journal of Journal of Clinical Periodontology, vol. 48, no. 12, pp. 1570-1586Contributions to Journals: Review articlesReciprocal organ interactions during heart failure-a position paper from the ESC working group on myocardial function
Cardiovascular Research, vol. 117, no. 12, pp. 2416–2433Contributions to Journals: ArticlesA toolbox for generating scalable mitral valve morphometric models
Computers in Biology and Medicine, vol. 135, 104628Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.compbiomed.2021.104628
Demographic, multi-morbidity and genetic impact on myocardial involvement and its recovery from COVID-19: protocol design of COVID-HEART-a UK, multicentre, observational study
Journal of Cardiovascular Magnetic Resonance, vol. 23, no. 1, 77Contributions to Journals: ArticlesA systematic review of biomarkers in Takotsubo syndrome: A focus on better understanding the pathophysiology
IJC Heart & Vasculature, vol. 34, 100795Contributions to Journals: ArticlesQuality assurance of quantitative cardiac T1-mapping in multicenter clinical trials: A T1 phantom program from the hypertrophic cardiomyopathy registry (HCMR) study
International Journal of Cardiology, vol. 330, pp. 251-258Contributions to Journals: ArticlesThe role of inflammation in stress cardiomyopathy
Trends in Cardiovascular Medicine, vol. 31, no. 4, pp. 225-230Contributions to Journals: Review articlesSex Differences in Ischemic Stroke Outcomes in Patients With Pulmonary Hypertension
Journal of the American Heart Association, vol. 10, no. 6, e019341Contributions to Journals: ArticlesMetabolic alterations in a rat model of Takotsubo syndrome
Cardiovascular Research, cva081Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/cvr/cvab081
The early dynamic of ECG in takotsubo syndrome presenting with ST-elevation: A comparison with age and gender-matched ST-elevation myocardial infarction
International Journal of Cardiology, vol. 323, pp. 125-125Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1016/j.ijcard.2020.09.023
- [ONLINE] View publication in Scopus
Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function
Cardiovascular Research, vol. 117, no. 1, pp. 43–59Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/cvr/cvaa110
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/16365/1/cvaa110.pdf
- [ONLINE] View publication in Scopus
Detection of periodontal microorganisms in coronary atheromatous plaque specimens of myocardial infarction patients: A systematic review and meta-analysis
Trends in Cardiovascular Medicine, vol. 31, no. 1, pp. 69-82Contributions to Journals: ArticlesThe Early Dynamic of ECG in Takotsubo Syndrome presenting with ST-elevation: A comparison with age and gender-matched ST-elevation Myocardial Infarction
International Journal of Cardiology, vol. 320, pp. 7-11Contributions to Journals: ArticlesEffect of the 2017 European Guidelines on Reclassification of Severe Aortic Stenosis and Its Influence on Management Decisions for Initially Asymptomatic Aortic Stenosis
Circulation. Cardiovascular imaging, vol. 13, no. 12, 011763Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1161/CIRCIMAGING.120.011763
Multimodality imaging in takotsubo syndrome: a joint consensus document of the European Association of Cardiovascular Imaging (EACVI) and the Japanese Society of Echocardiography (JSE)
European Journal of Echocardiography, vol. 18, pp. 199-224Contributions to Journals: ArticlesCardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs. Novel cardio-oncology insights from the joint 2019 meeting of the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart
Cardiovascular Research, vol. 116, no. 11, pp. 1820-1834Contributions to Journals: ArticlesGeometric description for the anatomy of the mitral valve: A review
Journal of Anatomy, vol. 237, no. 2, pp. 209-224Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/joa.13196
- [ONLINE] View publication in Scopus
T1 mapping performance and measurement repeatability: results from the multi-national T1 mapping standardization phantom program (T1MES)
Journal of Cardiovascular Magnetic Resonance, vol. 22, 31Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/s12968-020-00613-3
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14341/1/document.pdf
- [ONLINE] View publication in Scopus
An Update on Cardiac Magnetic Resonance Imaging in Takotsubo Cardiomyopathy
Current Cardiovascular Imaging Reports, vol. 13, no. 5, 17Contributions to Journals: Review articlesTakotsubo syndrome in Heart Failure and World Congress on Acute Heart Failure 2019: highlights from the experts
ESC Heart Failure, vol. 7, no. 2, pp. 400-406Contributions to Journals: Review articlesFast field-cycling magnetic resonance detection of intracellular ultra-small iron oxide particles in vitro: Proof-of-concept
Journal of Magnetic Resonance, vol. 313, 106722Contributions to Journals: ArticlesDeterminants of Exercise Capacity and Myocardial Perfusion Reserve in Asymptomatic Patients With Aortic Stenosis
JACC. Cardiovascular Imaging, vol. 13, no. 1 Part 1, pp. 178-180Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1016/j.jcmg.2019.08.008
- [ONLINE] View publication in Scopus
Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans
The American Journal of Clinical Nutrition, vol. 111, no. 1, pp. 79-89Contributions to Journals: ArticlesLifelong recurrent takotsubo cardiomyopathy: a case report
European Heart Journal - Case Reports, vol. 3, no. 4, pp. 1-5Contributions to Journals: ArticlesDistinct Subgroups in Hypertrophic Cardiomyopathy in the NHLBI HCM Registry
Journal of the American College of Cardiology, vol. 74, no. 19, pp. 2333-2345Contributions to Journals: ArticlesResponse by Scally and Dawson to Letters Regarding Article, “Myocardial and Systemic Inflammation in Acute StressInduced (Takotsubo) Cardiomyopathy”
Circulation, vol. 140, no. 13, pp. e698-e699Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1161/CIRCULATIONAHA.119.041878
- [ONLINE] View publication in Scopus
Reference range determination for imaging biomarkers: Myocardial T1
Journal of Magnetic Resonance Imaging, vol. 50, no. 3, pp. 771-778Contributions to Journals: ArticlesMatrix-dependent size modifications of iron oxide nanoparticles (Ferumoxytol) spiked into rat blood cells and plasma: Characterisation with TEM, AF4-UV-MALS-ICP-MS/MS and spICP-MS
Journal of Chromatography B, vol. 1124, pp. 356-365Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jchromb.2019.06.029
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/14562/1/Matrix_dependent_iron_oxide_NPs_Kenneth_Nwoko.pdf
- [ONLINE] https://linkinghub.elsevier.com/retrieve/pii/S1570023219304842
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
Aortic stiffness in aortic stenosis assessed by cardiovascular MRI: a comparison between bicuspid and tricuspid valves
European Radiology, vol. 29, no. 5, pp. 2340-2349Contributions to Journals: ArticlesDiastolic Ventricular Interaction in Heart Failure With Preserved Ejection Fraction
Journal of the American Heart Association, vol. 8, no. 7, e010114Contributions to Journals: ArticlesMyocardial and Systemic Inflammation in Acute Stress-Induced (Takotsubo) Cardiomyopathy
Circulation, vol. 139, no. 13, pp. 1581-1592Contributions to Journals: Articles- [ONLINE] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438459/
- [ONLINE] DOI: https://doi.org/10.1161/CIRCULATIONAHA.118.037975
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
- [ONLINE] http://europepmc.org/abstract/med/30586731
Takotsubo syndrome: State-of-the-art review by an expert panel – Part 2
Cardiovascular Revascularization Medicine, vol. 20, no. 2, pp. 153-166Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1016/j.carrev.2018.11.016
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Takotsubo syndrome: State-of-the-art review by an expert panel - Part 1
Cardiovascular revascularization medicine : including molecular interventions, vol. 20, no. 1, pp. 70-79Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1016/j.carrev.2018.11.015
- [ONLINE] View publication in Mendeley
Symptom Onset in Aortic Stenosis: Relation to Sex Differences in Left Ventricular Remodeling
JACC. Cardiovascular Imaging, vol. 12, no. 1, pp. 96-105Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jcmg.2017.09.019
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstream/2164/13761/1/Symptom_onset_in_aortic_stenosis.pdf
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Takotsubo: the myth of rapid and complete recovery
European Heart Journal, vol. 39, no. 42, pp. 3762-3763Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/eurheartj/ehy660
Response to Letters Regarding Article, "Persistent Long-Term Structural, Functional, and Metabolic Changes After Stress-Induced (Takotsubo) Cardiomyopathy"
Circulation, vol. 138, no. 9, pp. 962-963Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1161/CIRCULATIONAHA.118.035883
Complex roads from genotype to phenotype in dilated cardiomyopathy: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology
Cardiovascular Research, vol. 114, no. 10, pp. 1287-1303Contributions to Journals: ArticlesMetabolic changes in hypertrophic cardiomyopathies: Scientific update from the Working Group of Myocardial Function of the European Society of Cardiology
Cardiovascular Research, vol. 114, no. 10, pp. 1273-1280Contributions to Journals: ArticlesPreclinical Evaluation of [18F]LCATD as a PET Tracer to Study Drug-Drug Interactions Caused by Inhibition of Hepatic Transporters
Contrast Media & Molecular Imaging, vol. 2018, 3064751Contributions to Journals: ArticlesRegional expression of inflammatory and cardiac remodelling genes in a rat model of takotsubo cardiomyopathy
Annual Conference of the British-Cardiovascular-Society on High Performing Teams, pp. A79-A80Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1136/heartjnl-2018-BCS.97