Professor Dana Dawson

Professor Dana Dawson
Professor Dana Dawson

Professor Dana Dawson

DM, FRCP, D.Phil, FESC

Chair in Cardiovascular Medicine

About

Polwarth Building School of Medicine and Dentistry University of Aberdeen Foresterhill Aberdeen AB25 2ZD

Biography

Professor Dawson qualified in medicine at University of Medicine “Grigore T. Popa”, Iasi, Romania. After completing her MRCP with the Royal College of Physicians in London she read for a D. Phil in Cardiovascular Medicine at Merton College, University of Oxford.  She trained in Cardiovascular Medicine in Edinburgh, Oxford and London in the UK and at the University of Virginia, Charlottesville, in the USA.  In 2010 she moved to the University of Aberdeen and Aberdeen Royal Infirmary where she currently is Professor of Cardiovascular Medicine and Consultant Cardiologist.

She made a significant contribution in advancing knowledge in acute stress induced (Takotsubo) cardiomyopathy,  one of the main areas of research interest within the group. Several Takotsubo studies are ongoing and the Scottish Takotsubo Registry is accruing all incident and prevalent cases dating back to 2010.

There is keen interest in other topics such as diet and exercise based interventions to improve cardio-metabolic health in patients with type 2 diabetes, mechanistic trials exploring the cardiac substrate in patients with COPD who show clinical improvement whilst on betablocker therapy.  There is a developing interest in cardio-oncology and in therapies for acute coronary syndromes.

The group is working together with MR physicists towards the unique development of fast field cycling magnetic resonance for cardiovascular disease (with Professor David Lurie's group).

Professor Dana Dawson leads the Cardiology and Cardiovascular Research Unit and together with her NHS Consultant Colleagues who have distinct Principal Investigator roles, they bring specific expertise to the group, creating a broad scope of activities.

The Cardiology and Cardiovascular Research Unit also has strong collaborative links with molecular nutritionists, diabetes/endocrinology and oncology clinical colleagues, sport physiologists, MR and PET physicists, synthetic molecular chemists and cardio-thoracic surgeons.

Memberships and Affiliations

Internal Memberships

Team members and close collaborators:

Dr. Alice Mezincescu – Clinical Lecturer (former BHF Clinical Research Fellow)

Dr. Hassan Abbas – BHF Clinical Research Fellow

Dr. James Ross - Lecturer in Cardiovascular Magnetic Resonance Physics

Dr. David Gamble - BHF Clinical Research Fellow

Dr. Hilal Khan - Clinical Research Fellow

Dr. Maheshi Gunasekara - Clinical Research Fellow

Dr. Chaitanya Pradeep Joshi - Clinical Research Fellow - Dental, Elphinstone Scholar

Ms Amelia Rudd, MSc - BHF AHP Clinical Research Fellow

Miss Lesley Cheyne - Cardiovascular Technician

Ms Janaki Srivanastan – Senior Research Sonographer

Dr. Lionel Broche – Lecturer in Fast Field Cycling MR Physics

Dr. Gareth Davies - Fast Field Cycling MR Physics Reseach Fellow

Dr. Caroline Scally – former BHF Clinical Research Fellow

Miss Nadine Godsman – former BHF non-clinical PhD student

 Nursing staff:

RN Valerie Harries

RN Paula Henderson

Research Radiographers:

Ms Nicola Crouch (MRI)

Mr Mike Hendry (MRI)

Ms Laura Reid (MRI)

Mrs Denise Forrest (CT)

Ms Louise Lamley (CT)

 

External Memberships

She is a member of the British Cardiovascular Society, American Heart Association, Fellow of the European Society of Cardiology (ESC), chair-elect of the Myocardial Function Working Group (ESC) and a Committee member of the Takotsubo Syndrome Study Group.

Prizes and Awards

Most recent mentored scientific investigations shortlisted for prize awards include:

1.    Janaki Srivanasan – winner of the British Society of Echocardiography Young Investigator Research Prize, October 2016

2.    Caroline Scally – finalist at the Early Career award, Society of Cardiovascular Magnetic Resonance, Washington, January 2017

3.    Caroline Scally – finalist at the Samuel A Levine Young Investigator Award of the American Heart Association, Anaheim, CA, November 2017

4.    Nadine Godsman – winner of the Young Investigator’s prize of the British Pharmacological Society – Pharmacology, December 2017 – London, England

5.    Caroline Scally - finalist at the Melvin Judkins Young Investigator Award of the American Heart Association, Chicago, IL, November 2018

6.    Alice Mezincescu – finalist at the Early Career Award-Translational Sciences of the Society of Cardiovascular Magnetic Resonance, Seattle, February 2019

Research

Funding and Grants

RESEARCH GRANTS  – current:

  1. Replacement of (ultrasound) echocardiography equipment for clinical research, BHF Infrastructure Grant IG/F/21/50010, D Dawson, 2022, £73,604
  2. Epigenetic Phase Variation of Periodontal Bacteria – a Mechanistic Contributor to Coronary Artery Disease, BHF Clinical Research Training Fellowship - FS/CRTF/22/24275, K Hijazi (PI) and D Dawson, £217,509, 2022-2025
  3. Epidemiology and predisposition of acute stress-induced (takotsubo) Cardiomyopathy - BHF Research Training Fellowship (FS/RTF/20/30009, for Ms Amelia Rudd): D Dawson (CI), David Newby, 2021-2023, £215,051
  4. Demographic, multi-morbidity and genetic impact on myocardial involvement and its recovery from Covid-19: The Covid-Heart Study, NIHR, CI John Greenwood, D Dawson co-applicant, £775,095
  5. The next leap in cardiac magnetic resonance imaging: cycling the field: D Dawson (CI), D Lurie, L Broche, J Ross, H Abbas: BHF New Horizons Grant no. NH/19/1/34595, 2020-2024, £277,722
  6. Towards Elucidating the Genetic Predisposition for Acute Stress-Induced (Takostubo) Cardiomyopathy: D Dawson (Chief Investigator), Z Miedzybrodzka, Chest Heart and Stroke Scotland, 2019-2021, £24,950
  7. PhysicaL Exercise and mental wellbeing rehabilitation for Acute StrEss-induced takotsubo cardiomyopathy: The PLEASE trial BHF Project Grant no. PG/18/35/33786; D Dawson (Chief Investigator), D.E. Newby, Marc Petrie, S Leslie, C.C. Lang, G Horgan, S Gray, C Williams, 2019-2022, £298,134
  8. Cardiac Energetics and Breast Cancer Treatment, Tenovus Scotland 01, D Dawson (Chief Investigator), R Sharma, 2019-2021, £19,595
  9. Resting Cardiac Energetics in Patients Undergoing Anthracycline Chemotherapy for Breast Cancer, Friends of Anchor, D Dawson (Chief Investigator), R Sharma, 2019-2021, £14,724
  10. Fast Field Cycling-Magnetic Resonance Imaging (FFC-MRI): A New Diagnostic that Reveals Acutely Inflamed Coronary Artery Plaques by Detecting Fat Dysfunction: D Dawson (Chief Investigator), D Lurie, L Broche, Justin Rochford and Hussein El-Shafei, Grampian NHS-Endowments, 2018-2020, £9,350
  11. A randomised, double-blind placebo controlled trial to test if a beneficial effect of beta-blockers on exacerbations of chronic obstructive pulmonary disease (COPD) is restricted to those patients with occult heart disease: D Dawson (Chief Investigator), G Devereux, C Lang, B Lipowrth, W MacNee, N Mills, S Fielding, R Chaudhuri, P Short: BHF Project Grant no. PG/17/64/33205, 2018-2022, £299,169
  12. Duration of dual anti-platelet therapy in acute coronary syndrome across Scotland. The DUAL-ACS2 trial: D Newby (Chief Investigator), N Mills, K Fox, D Dawson, J Irving, D McAllister, A Morris, J Norrie, M Petrie, C Berry, M McEntegart: British Heart Foundation Clinical Study no. CS/17/4/32960, 2017-2022, £630,845
  13. Muscle fat compartments and turnover as a determinant of insulin sensitivity: D Dawson (Chief Investigator), M Delibegovic, S Gray, S Philip, P Whitfield, F Thies, G Lobley, British Heart Foundation Project Grant no. PG/15/88/31780, £259,358, 2016-2020
Publications

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  • Myocardial Involvement After Hospitalization for COVID-19 Complicated by Troponin Elevation: A Prospective, Multicenter, Observational Study

    Artico, J., Shiwani, H., Moon, J. C., Gorecka, M., McCann, G. P., Roditi, G., Morrow, A., Mangion, K., Lukaschuk, E., Shanmuganathan, M., Miller, C. A., Chiribiri, A., Prasad, S. K., Adam, R. D., Singh, T., Bucciarelli-Ducci, C., Dawson, D., Knight, D., Fontana, M., Manisty, C., Treibel, T. A., Levelt, E., Arnold, R., Macfarlane, P. W., Young, R., McConnachie, A., Neubauer, S., Piechnik, S. K., Davies, R. H., Ferreira, V. M., Dweck, M. R., Berry, C., Greenwood, J. P., OxAMI (Oxford Acute Myocardial Infarction Study) Investigators; COVID-HEART Investigators†
    Circulation, vol. 147, no. 5, pp. 364-374
    Contributions to Journals: Articles
  • Structural and functional brain changes in acute Takotsubo Syndrome

    Khan, H., Gamble, D., Rudd, A., Mezincescu, A., Abbas, H., Noman, A., Stewart, A., Horgan, G., Krishnadas, R., Williams, C., Waiter, G., Dawson, D.
    JACC. Heart failure
    Contributions to Journals: Articles
  • Manganese-Enhanced Magnetic Resonance Imaging in Takotsubo Syndrome

    Singh, T., Joshi, S., Kershaw, L. E., Baker, A. H., McCann, G. P., Dawson, D. K., Dweck, M. R., Semple, S. I., Newby, D. E.
    Circulation, vol. 146, no. 24, pp. 1823-35
    Contributions to Journals: Articles
  • Myocardial infarction risk is increased by periodontal pathobionts: a cross-sectional study

    Joshi, C., Mezincescu, A., Gunasekara, M., Rudd, A., Botchorichvili, H., Sabir, S., Dospinescu, C., Noman, A., Hogg, D., Cherukara, G., McLernon, D., Hijazi, K., Dawson, D.
    Scientific Reports, vol. 12, no. 1, 18608
    Contributions to Journals: Articles
  • Myocarditis Following SARS-CoV2 mRNA Vaccination Against COVID-19: Facts and Open Questions

    Heymans, S., Dawson, D., Fuster, V., Metra, M., Tocchetti, C. G.
    Journal of the American College of Cardiology, vol. 80, no. 14, pp. 1363-1365
    Contributions to Journals: Articles
  • Renin-Angiotensin and Endothelin Systems in Patients post Takotsubo Cardiomyopathy

    Khan, M. H. W., Newby, D. E., Cheyne, L., Gamble, D., Horgan, G., Dawson, D., Dhaun, N., Rudd, A., Mezincescu, A.
    Journal of the American Heart Association, vol. 11, no. 14, e025989
    Contributions to Journals: Articles
  • Psilocybin-induced takotsubo cardiomyopathy

    Kotts, W. J., Gamble, D. T., Dawson, D. K., Connor, D.
    BMJ Case Reports, vol. 15, no. 5, e245863
    Contributions to Journals: Articles
  • Optimization of an RF Array for Cardiac Magnetic Resonance at 8.5 MHz

    Davies, G., Stormont, R. S., Broche, L., Dawson, D., Lurie, D., Ross, J.
    Joint Annual Meeting ISMRM-ESMRMB
    Contributions to Conferences: Abstracts
  • Metabolic alterations in a rat model of Takotsubo syndrome

    Godsman, N., Kohlhaas, M., Nickel, A., Cheyne, L., Mingarelli, M., Schweiger, L., Hepburn, C., Munts, C., Welch, A., Delibegovic, M., van Bilsen, M., Maack, C., Dawson, D.
    Cardiovascular Research, vol. 118, no. 8, pp. 1932–1946
    Contributions to Journals: Articles
  • Use of the oral beta blocker bisoprolol to reduce the rate of exacerbation in people with chronic obstructive pulmonary disease (COPD): a randomised controlled trial. (BICS)

    Cotton, S., Devereux, G., Abbas, H., Briggs, A. H., Campbell, K., Chaudhuri, R., Choudhury, G., Dawson, D., De Soyza, A., Fielding, S., Gompertz, S., Haughney, J., Lang, C. C., Lee, A., MacLennan, G., MacNee, W., McCormack, K., McMeekin, N., Mills, N. L., Morice, A., Norrie, J., Petrie, L., Price, D., Short, P., Vestbo, J., Walker, P., Wedzicha, J. A., Wilson, A., Lipworth, B. J.
    Trials, vol. 23, no. 1, 307
    Contributions to Journals: Articles
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