BSc (Aberdeen, 1991), PhD (London, 1994). Recipient of the College of Life Sciences and Medicine award for Excellence in Teaching, 2009 and of the Aberdeen University Students Association award for Most Accessible Lecturer (Champion for Disabilities), 201
Derryck Shewan graduated in Physiology from the University of Aberdeen in 1991, having gained a particular interest in the mechanisms of axon guidance. He undertook a studentship with Prof Jim Cohen at Guy’s Hospital Medical School, under the co-supervision of Prof Martin Berry, in the Developmental Neurobiology department, which has since evolved to the MRC Unit for Developmental Neurobiology at Hunt’s House, Kings College London. He gained his PhD in Anatomy and Cell Biology in 1994 having studied mechanisms of axon growth and regeneration, building up an appreciation of the changing nature of neuronal behaviour during development. In 1994 Dr Shewan was appointed a Research Fellow in Dr Cohen’s laboratory, which involved some time working with Dr Geneviève Rougon and her colleagues at the CNRS Faculté des Sciences de Luminy in Marseille. In 1997 he moved to the Department of Anatomy at the University of Cambridge as a Research Associate in Prof Christine Holt’s laboratory. Having spent 3 years studying the development of the visual system, Dr Shewan moved on in 2000 to the Department of Physiology at the University of Cambridge as a Research Associate in Professor James Fawcett’s laboratory. In 2001 he moved with Professor Fawcett’s group to he Cambridge Centre for Brain Repair. Dr Shewan was appointed Lecturer in Biomedical Sciences at the University of Aberdeen in 2003, and promoted to Senior Lecturer in 2006. He now forms part of the Aberdeen University Spinal Injury Research Group. He was afforded the College of Life Sciences and Medicine Award for Excellence in Teaching in 2009, nominated again in 2010, nominated for the Students Association award for Supporting Students in 2011 and afforded the Students Association award for most Accessible Lecturer (Champion for Disabilities) in 2016.
Dr Shewan is interested in the changing intracellular signalling mechanisms that accompany neuronal maturation. In particular, he focuses on the growth and regenerative capacities of embryonic and adult neurons in order to find differences that may help to explain why neurons of the central nervous system become incapable of regenerating after injury. A more detailed synopsis of Dr Shewan's work can be found at the Cell and Developmental Biology Research Theme at the University of Aberdeen.
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I am the co-ordinator of Biomedical Sciences Honours year research projects (BM4501, DB 4501, PA4501, PY4501 and SR4501).
Also at Level 4 I deliver lectures on axon guidance andÂ contributeÂ to courseÂ assessmentsÂ on theÂ HonoursÂ yearÂ coreÂ courseÂ onÂ AdvancedÂ Molecules,Â MembranesÂ andÂ CellsÂ (BM4004), as well as lecture on Sensory Systems and participate in the assessment of student seminars on Brain Function and Malfunction (AN4002).
At level 2Â IÂ presentÂ andÂ demonstrate on Foundation Skills for Life Sciences (BI2005) and also tutor and act as Theme leader for 'Nervous System Diseases' on the Research Skills for Life Sciences course (BI2506). I deliver lectures on Sensory Systems on Physiology of Human Cells (BI20B2).
I co-ordinate the DevelopMental Theme for the Phase 1 MBChB Student Selected Module 1.
IÂ participate in University Open,Â ApplicantÂ and Induction days, and host School visits for secondary school pupils.
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cAMP-Dependent Axon Guidance is Distinctly Regulated by Epac and Protein Kinase AJournal of Neuroscience, vol. 29, no. 49, pp. 15434-15444Contributions to Journals: Articles
cGMP promotes neurite outgrowth and growth cone turning and improves axon regeneration on spinal cord tissue in combination with cAMPBrain Research, vol. 1294, pp. 12-21Contributions to Journals: Articles
B-raf Regulates cAMP-Dependant Axon Growth and GuidanceScottish Neuroscience Group Annual Meeting (2009)Contributions to Conferences: Posters
B-raf regulates cAMP-dependent axon growth and guidanceScottish Neuroscience Group Meeting 2009Contributions to Conferences: Posters
Epac promotes axon regeneration in vitroContributions to Conferences: Papers
Epac mediates cyclic AMP-dependent axon growth, guidance and regenerationMolecular and Cellular Neuroscience, vol. 38, no. 4, pp. 578-588Contributions to Journals: Articles
Differential mechanisms of cAMP signalling in astrocyte-mediated inhibition of axon regenerationSociety for Neuroscience Annual Meeting (2008)Contributions to Conferences: Posters
The use of FRET sensors to examine age-dependent signalling mechanisms in DRG growth conesSociety for Neuroscience Annual Meeting (2008)Contributions to Conferences: Posters
Distinct Mechanisms of cAMP-Dependent Axon GuidanceSociety for Neuroscience Annual Meeting (2007)Contributions to Conferences: Posters
Neuronal Signalling Pathways Controlling Axon Growth and RegenerationScottish Neuroscience Group Annual Meeting (2007)Contributions to Conferences: Posters