FRSE
Emeritus Professor
- About
-
- Email Address
- alison.murray@abdn.ac.uk
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Professor Emerita (Radiology) with expertise in brain MRI correlates of cognitive ageing in the Aberdeen Birth Cohorts and in molecular brain imaging in TauRx clinical trials of novel therapeutics in Alzheimer's disease.
Consultant radiologist then honorary consultant NHS Grampian (1995-2020) with expertise in neuroradiology and molecular imaging.
Qualifications
- MB ChB (Hons) Medicine1985 - University of Aberdeen
- MRCP Medicine1988 - Royal College of Physicians & Surgeons of Glasgow
- FRCR Radiology1992 - Royal College of Radiologists UK
- PhD Medical Sciences2013 - University of Aberdeen
PhD Thesis November 2012 “Brain white matter hyperintensities: Correlates in normal ageing and relevance in Alzheimer’s disease.” Successfully defended January 2013
External Memberships
Fellow and council member of the Royal Society of Edinburgh
Chairperson Roland Sutton Academic Trust
Treasurer and Trustee Campaign for Evidence Based Healthcare
Trustee TENOVUS Scotland (Grampian Highlands and Islands)
Volunteer North-East Scotland Coastal Trust
Latest Publications
The Influence of Birth Weight, Socio-Economic Status, and Adult Health on Brain Volumes during Ageing
Neuroepidemiology, vol. 59, no. 5, pp. 489-497Contributions to Journals: ArticlesFDG-PET Image Classification in Alzheimer’s Disease: from Traditional Visual Analysis to Advanced Transfer Learning
Nuclear Medicine and Molecular Imaging, vol. 59, pp. 201-208Contributions to Journals: Articles- [ONLINE] https://pubmed.ncbi.nlm.nih.gov/40385367/
- [ONLINE] DOI: https://doi.org/10.1007/s13139-025-00908-2
Myelin mapping in patients with rheumatoid arthritis-related fatigue: a TBSS-MTR study of integrity
BJR Open, vol. 7, no. 1, tzaf014Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/bjro/tzaf014
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/66cb5473-3395-42ea-a4ef-c9c5319b63fe/download
- [ONLINE] View publication in Scopus
Phantom study investigating the repeatability of radiomic features with alteration of image acquisition parameters in magnetic resonance imaging
Journal of Medical Imaging and Radiation Sciences, vol. 55, no. 1, pp. 19-28Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jmir.2023.10.003
- [ONLINE] View publication in Scopus
The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions
Nature Genetics, vol. 55, no. 3, pp. 423-436Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/s41588-023-01323-z
- [ONLINE] View publication in Scopus
Prizes and Awards
FRSE (2017-)
- Research
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Supervision
Dr Sima Salarirad (2011) “The relative contributions of imaging biomarkers of cerebrovascular and Alzheimer’s diseases to cognitive ageing”
Dr Moses Olufemi Sokunbi (2011) “Functional MRI entropy measurements of brain complexity”
Dr Ivan Roijals Miras (2012) “Information processing speed and information flow in the ageing brain”
Dr Dorota Chapko (2016) “Life-course determinants of resilience to cognitive ageing”
Dr Maryam Hashim (2016) 3rd supervisor “Optimisation of MRI for neuroimaging in inflammatory diseases”
Dr Maria Goni (2018) 3rd supervisor “Imaging correlates of fatigue in inflammatory disease”
Dr Clarisse De Vries – (2020) “Early life and life-course predictors of brain entropy and functional connectivity.
Dr Jennifer Waymont (2020) “Automated detection of brain lesions in the Aberdeen Children of the 1950s and analysis of lifecourse determinants”
Dr Shaun Stone (2021) “Prediction models of dementia risk from brain MR images and proxies of cognitive reserve”
Dr Mina Kherzian (2021) “Investigating the role of polypharmacy in brain ageing, and cognitive, physical and emotional impairment in three well characterised cohort studies in Aberdeen”
Dr Shailendra Mohan Tripathi (2021) “Machine learning in classification of Alzheimer’s disease diagnosis and response to treatment”
- Publications
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Page 1 of 4 Results 1 to 50 of 181
The Influence of Birth Weight, Socio-Economic Status, and Adult Health on Brain Volumes during Ageing
Neuroepidemiology, vol. 59, no. 5, pp. 489-497Contributions to Journals: ArticlesFDG-PET Image Classification in Alzheimer’s Disease: from Traditional Visual Analysis to Advanced Transfer Learning
Nuclear Medicine and Molecular Imaging, vol. 59, pp. 201-208Contributions to Journals: Articles- [ONLINE] https://pubmed.ncbi.nlm.nih.gov/40385367/
- [ONLINE] DOI: https://doi.org/10.1007/s13139-025-00908-2
Myelin mapping in patients with rheumatoid arthritis-related fatigue: a TBSS-MTR study of integrity
BJR Open, vol. 7, no. 1, tzaf014Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/bjro/tzaf014
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/66cb5473-3395-42ea-a4ef-c9c5319b63fe/download
- [ONLINE] View publication in Scopus
Phantom study investigating the repeatability of radiomic features with alteration of image acquisition parameters in magnetic resonance imaging
Journal of Medical Imaging and Radiation Sciences, vol. 55, no. 1, pp. 19-28Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.jmir.2023.10.003
- [ONLINE] View publication in Scopus
The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions
Nature Genetics, vol. 55, no. 3, pp. 423-436Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/s41588-023-01323-z
- [ONLINE] View publication in Scopus
Structural brain correlates of childhood trauma with replication across two large, independent community-based samples
European Psychiatry, vol. 66, no. 1, e19Contributions to Journals: ArticlesFrancis William Smith, MD, FRCR, FRCS, FRCP, FFSEM (UK) (1943-2022)
Journal of Magnetic Resonance Imaging, vol. 57, no. 1, pp. 324-325Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1002/jmri.28552
- [ONLINE] View publication in Scopus
Alzheimer’s Dementia: The Emerging Role of Positron Emission Tomography
The Neuroscientist, vol. 28, no. 5Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1177/1073858421997035
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/429ec665-7386-419f-853b-8e1110b9bd5a/download
- [ONLINE] View publication in Scopus
Cognitive Test Scores and Progressive Cognitive Decline in the Aberdeen 1921 and 1936 Birth Cohorts
Brain Sciences, vol. 12, no. 3, 318Contributions to Journals: ArticlesHaemoglobin Concentration and Cognitive Ability in the Aberdeen Children of the 1950s
Cureus, vol. 14, no. 2, e21806Contributions to Journals: ArticlesEpigenome-wide association study of global cortical volumes in Generation Scotland: Scottish Family Health Study
Epigenetics, vol. 17, no. 10, pp. 1143–1158Contributions to Journals: ArticlesThe use of PET/MRI in Dementia: A Literature Review
International Journal of Geriatric Psychiatry, vol. 36, no. 10, pp. 1501-1513Contributions to Journals: Review articles- [ONLINE] DOI: https://doi.org/10.1002/gps.5586
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/03132325-493a-4f4f-96dc-48dfbffebf07/download
Degeneration of basal and limbic networks is a core feature of behavioural variant frontotemporal dementia
Brain Communications, vol. 3, no. 4, fcab241Contributions to Journals: ArticlesSpectral Clustering Based on Structural Magnetic Resonance Imaging and its Relationship with Major Depressive Disorder and Cognitive Ability
European Journal of Neuroscience, vol. 54, no. 6, pp. 6281-6303Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/ejn.15423
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/0fcbc2ab-375a-44a8-ad0c-c882f54eb78e/download
- [ONLINE] View publication in Scopus
Early life predictors of late life cerebral small vessel disease in four prospective cohort studies
Brain, vol. 144, no. 12, pp. 3769–3778Contributions to Journals: ArticlesA cross-cohort study: sexual dimorphism in the relationship between brain complexity & intelligence
Organization for Human Brain Mapping meetingContributions to Conferences: AbstractsImprinting methylation predicts hippocampal volumes and hyperintensities and the change with age in later life
Scientific Reports, vol. 11, 943Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/s41598-020-78062-2
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/f435d98d-e4e4-4833-968c-fc8a75722c74/download
- [ONLINE] View publication in Scopus
Cohort profile for the STratifying Resilience and Depression Longitudinally (STRADL) study: A depression-focused investigation of Generation Scotland, using detailed clinical, cognitive, and neuroimaging assessments
Wellcome open research, vol. 4, 185Contributions to Journals: ArticlesCirculating asymmetric dimethylarginine and cognitive decline: A 4‐year follow‐up study of the 1936 Aberdeen Birth Cohort
International Journal of Geriatric Psychiatry, vol. 35, no. 10, pp. 1181-1188Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/gps.5355
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/5ea5c253-6790-4fed-9b68-71e0c18c07e4/download
- [ONLINE] View publication in Scopus
iCAIRD – a Safe Haven model for NHS, Academia, and Industry partnership in AI.
Faculty of Clinical Informatics Annual Scientific MeetingContributions to Conferences: AbstractsAutomated classification of depression from structural brain measures across two independent community‐based cohorts
Human Brain Mapping, vol. 41, no. 14, pp. 3922-3937Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/hbm.25095
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/14afe8c1-3ac5-4f7c-86fa-182c7421c459/download
- [ONLINE] View publication in Scopus
Blunted medial prefrontal cortico-limbic reward-related effective connectivity and depression
Brain, vol. 143, no. 6, pp. 1946-1956Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/brain/awaa106
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/fe87a5d3-1dfb-4481-afc2-9340238e9370/download
- [ONLINE] View publication in Scopus
Brain hyperintensities in magnetic resonance imaging of patients with mild acute focal neurology
Neurological Sciences, vol. 41, no. 6, pp. 1633-1635Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s10072-020-04256-1
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/dda49684-e74f-46f7-a9a2-6697a3e79591/download
- [ONLINE] View publication in Scopus
Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia
Journal of Alzheimer's Disease, vol. 75, no. 2, pp. 501-519Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3233/JAD-191173
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/53b6ee0c-d5be-45c3-90a0-1afea8f620c4/download
- [ONLINE] View publication in Scopus
Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose
PloS ONE, vol. 15, no. 5, pp. e0230815Contributions to Journals: ArticlesAspirin moderates the association between cardiovascular risk, brain white matter hyperintensity total lesion volume and processing speed in normal ageing
Maturitas, vol. 133, pp. 49-53Contributions to Journals: ArticlesKlotho gene polymorphism, brain structure and cognition in early-life development
Brain Imaging and Behavior, vol. 14, pp. 213-225Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s11682-018-9990-1
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/5b4b49b1-d838-4db1-8272-4006c4d9533e/download
- [ONLINE] View publication in Scopus
Motion during Acquisition is Associated with fMRI Brain Entropy
IEEE journal of biomedical and health informatics, vol. 24, no. 2, pp. 586-593Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1109/JBHI.2019.2907189
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/bf2be340-591e-41ba-ac93-18dd6edd574e/download
- [ONLINE] View publication in Mendeley
- [ONLINE] https://abdn.pure.elsevier.com/en/en/researchoutput/motion-during-acquisition-is-associated-with-fmri-brain-entropy(29372db1-d432-4fbd-a73a-468872424e30).html
- [ONLINE] View publication in Scopus
Validation and comparison of two automated methods to quantify brain white matter hyperintensities of presumed vascular origin
Journal of International Medical Research, vol. 48, no. 2, pp. 1-12Contributions to Journals: ArticlesAssociation of Inflammation With Pronociceptive Brain Connections in Rheumatoid Arthritis Patients With Concomitant Fibromyalgia
Arthritis & Rheumatology, vol. 72, no. 1, pp. 41-46Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/art.41069
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/fc02bbfb-924d-4741-8ee3-86b2cedc050f/download
- [ONLINE] View publication in Scopus
An overview of prevalence, determinants and health outcomes of polypharmacy
Therapeutic Advances in Drug Safety, vol. 11, pp. 1-10Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1177/2042098620933741
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/f0b3e86e-f927-4c61-b62c-789ae2d53060/download
- [ONLINE] View publication in Scopus
An epigenome-wide association study of sex-specific chronological ageing
Genome Medicine, vol. 12, 1Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.7488/ds/2709
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/be106bb1-afe9-430a-a370-8bd5b09c687b/download
Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer’s Disease
Journal of Alzheimer's Disease, vol. 72, no. 3, pp. 931-946Contributions to Journals: ArticlesA meta-analysis of genome-wide association studies of epigenetic age acceleration
PLoS Genetics, vol. 15, no. 11, e1008104Contributions to Journals: ArticlesAssociations of autozygosity with a broad range of human phenotypes
Nature Communications, vol. 10, 4957Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/s41467-019-12283-6
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/7e2baf94-5971-4342-a341-19aab711e29f/download
- [ONLINE] View publication in Scopus
Functional and structural magnetic resonance imaging correlates of fatigue in patients with rheumatoid arthritis
Rheumatology, vol. 58, no. 10, pp. 1822-1830Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/rheumatology/kez132
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/f3b61e5d-f826-44bd-a606-acc3266cd03e/download
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing
Genome Research, vol. 11, 54Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/s13073-019-0667-1
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/9ad0f53b-f763-4f27-b05d-b3314d2d79b2/download
- [ONLINE] https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-019-0667-1
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
AI could be our radiologists of the future, amid a healthcare staff crisis
The ConversationContributions to Specialist Publications: ArticlesP2-410: A RISK FACTOR PROFILE OF INCREASED WHITE MATTER HYPERINTENSITY BURDEN IN THE ABERDEEN CHILDREN OF THE NINETEEN FIFTIES COHORT
Chapters in Books, Reports and Conference Proceedings: Conference Proceedings- [ONLINE] DOI: https://doi.org/10.1016/j.jalz.2019.06.2817
Differences in brain functional connectivity networks between cognitive decliners and sustainers
SINAPSE Annual Scientific Meeting 2019Contributions to Conferences: AbstractsInsulin resistance: Genetic associations with depression and cognition in population based cohorts
Experimental Neurology, vol. 316, pp. 20-26Contributions to Journals: ArticlesMulti-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies novel loci associated with serum lipids
Nature Genetics, vol. 51, no. 4, pp. 636-648Contributions to Journals: Articles- [ONLINE] https://rdcu.be/buCgc
- [ONLINE] DOI: https://doi.org/10.1038/s41588-019-0378-y
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/66a142a3-bc54-439a-a9a9-91b8f6f0b909/download
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort
International Journal of Obesity, vol. 43, pp. 1795-1802Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/s41366-018-0262-3
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/7e90939e-abd4-46f9-b4a5-d329da337373/download
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries
Nature Genetics, vol. 51, no. 3, pp. 481-493Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/s41588-018-0321-7
- [ONLINE] View publication in Mendeley
Imprinting methylation in SNRPN and MEST1 in adult blood predicts cognitive ability
PloS ONE, vol. 14, no. 2, e0211799Contributions to Journals: ArticlesThe association between polypharmacy and late life deficits in cognitive, physical and emotional capability: a cohort study
International Journal of Clinical Pharmacy, vol. 41, no. 1, pp. 251-257Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s11096-018-0761-2
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/23b6e0c9-44ac-4507-8704-0a8c91a8e5e9/download
- [ONLINE] View publication in Mendeley
The Neurobiology of Personal Control During Reward Learning and Its Relationship to Mood
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, vol. 4, no. 2, pp. 190-199Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.bpsc.2018.09.015
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/621b436f-3b8b-4e40-8d59-532bda306dc0/download
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
Nature Communications, vol. 10, no. 1, 376Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/s41467-018-08008-w
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/e024a7df-4bb3-4aff-bb5c-bd621e3a8eb8/download
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Cortical Thickness and Surface Area Networks in Healthy Aging, Alzheimer’s Disease and Behavioral Variant Fronto-Temporal Dementia
International Journal of Neural Systems, vol. 29, no. 6, 1850055Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1142/S0129065718500557
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/8d52863b-34a5-4944-aa97-15d36af20879/download
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
Nature Neuroscience, vol. 21, no. 12, pp. 1656-1669Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/s41593-018-0275-1