BSc (Hons), PhD
Research Fellow
- About
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- Email Address
- alasdair.leeson-payne@abdn.ac.uk
- Office Address
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Alasdair Leeson-Payne graduated from the University of Aberdeen with a BSc in Neuroscience with Psychology (BioBusiness) in 2015. He continued his studies in Aberdeen, with an EastBio (BBSRC) Doctoral Training Partnership award, researching the metabolic pathways involved in adipose tissue energy expenditure. This work was carried out under the supervision of Dr Justin Rochford at the Rowett Institute and he graduated with a PhD in Medical Sciences in 2020. Alasdair joined Prof Lora Heisler’s Lab following his doctoral studies and is currently researching the neuronal regulation of appetite and energy expenditure.
Qualifications
- BSc Neuroscience with Psychology (BioBusness)2015 - University of Aberdeen
- PhD Medical Sciences2020 - University of Aberdeen
Memberships and Affiliations
- Internal Memberships
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ECR Member of the Equality and Diversity Team at the Rowett Institute (Subgroup lead Social and Culture)
- External Memberships
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Member of the British Society for Neuroendocrinology (BSN) and member of the ECR Sub-Committee
Member of the British Neuroscience Association (BNA)
Professional Member of DiabetesUK
- Research
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Research Overview
Our research aims to understand how the body regulates appetite and energy expenditure. This work focuses on how the brain, and different neurological circuits, sense and respond to changes in energy balance.
We aim to discover how brain circuits regulate energy balance with the purpose of identifying new treatments for obesity and type 2 diabetes. The goal of our research is to find novel medications to treat these diseases.
Our research also involves understanding how diet, body weight, and body composition affects and alters neuronal circuits and how we can correct these in disease states to treat obesity and diabetes.
This is part of our lab’s work programme on understanding Mechanisms Of Obesity, Metabolism, Insulin Senstivity and Nutrition (MOOMIN).

Research Areas
Biomedical Sciences
Nutrition and Health
Research Specialisms
- Diabetes
- Neuroscience
- Medical Sciences
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is HESA open data, published under the Creative Commons Attribution 4.0 International licence.
- Publications
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Loss of GPR75 protects against non-alcoholic fatty liver disease and body fat accumulation
Cell Metabolism, vol. 36, no. 5, pp. 1076-1087Contributions to Journals: ArticlesObesity medication lorcaserin activates brainstem GLP-1 neurons to reduce food intake and augments GLP-1 receptor agonist induced appetite suppression
Molecular Metabolism, vol. 68, 101665Contributions to Journals: ArticlesGuanidinoneomycin-Maleimide Molecular Transporter: Synthesis, Chemistry and Cellular Uptake
Organic & Biomolecular Chemistry, vol. 19, no. 29, pp. 6513-6520Contributions to Journals: ArticlesPhosphoprotein enriched in astrocytes (PEA)-15 is a novel regulator of adipose tissue expansion
Scientific Reports, vol. 11, 6949Contributions to Journals: ArticlesA refined rat primary neonatal microglial culture method that reduces time, cost and animal use
Journal of Neuroscience Methods, vol. 304, pp. 92-102Contributions to Journals: ArticlesCalmodulin is responsible for Ca2+-dependent regulation of TRPA1 Channels
Scientific Reports, vol. 7, 45098Contributions to Journals: Articles