STOPPIT-2 was a multi-centre randomised controlled trial, funded by the NIHR HTA Programme investigating whether the Arabin cervical pessary prevents preterm birth in women with a twin pregnancy and a short cervix. Patients with a short cervix (≤30mm) who agree to participate in the treatment phase of the study were randomised to either treatment with the Arabin cervical pessary or to standard care (no additional treatment).

STOPPIT-2 randomised 500 participants.

The primary endpoint of the trial is birth before 34+0 weeks following the spontaneous onset of labour.

STOPPIT-2 was led by Professor Jane Norman based at the University of Edinburgh.

For more information see the STOPPIT-2 Study Website