Male synthetic sling versus Artificial urinary Sphincter for men with urodynamic stress incontinence after prostate surgery: Evaluation by Randomised controlled trial (MASTER)
Around one in five patients who undergo prostate surgery (for cancer or benign disease) need to use incontinence pads because of leaking urine. The male synthetic sling (male sling) is an alternative to the artificial urinary sphincter (AUS) for people with urodynamic stress incontinence after prostate surgery, but there is limited evidence of relative effectiveness and cost-effectiveness to guide choice. We aim to resolve this by directly comparing the rate of incontinence at 12 months.
MASTER is a multicentre randomised controlled trial, funded by the NIHR HTA Programme.
The MASTER trial aims to compare male sling surgery with artificial urinary sphincter surgery in 360 men with urodynamic stress incontinence after prostate surgery, over 3 years.
The primary outcome is clinical and cost effectiveness of the male sling compared with an artificial urinary sphincter using the participant's report of incontinence at 12 months.
The MASTER trial is led by Professor Paul Abrams based at the Bristol Urological Institute.
MASTER closed to recruitment in 31 December 2017.
For more information please see the MASTER Study Website
- Lynda Constable; email@example.com
StatusOngoing - Data Collection/ In Follow Up
MASTER protocol publication http://rdcu.be/Hxkf