M.Sc., Ph.D., AFHEA.,
Advanced Research Fellow
- About
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- Email Address
- amalraj.raja@abdn.ac.uk
- Telephone Number
- +44 (0)1224 437147
- Office Address
Telephone :01224-437147 Fax :01224 437857 Medical Statistics Team Division of Applied Health Sciences University of Aberdeen Polwarth Building Foresterhill ABERDEEN AB25 2ZD UK
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Edwin Amalraj Raja joined Public Health as a Research Fellow in Medical Statistics in May 2006. In 1983, Edwin Amalraj Raja got his undergraduate degree in Statistics from St.Joseph's College, Trichy, India and postgraduate degree in Statistics from Loyola College, Chennai, India.
Edwin Amalraj Raja completed advanced training on the application of Statistics in the Department of Biostatistics, Christian Medical College, Vellore. He worked in 'Advanced Center for Clinical Epidemiological Research and Training Centre' at Madras Medical College, Chennai. His work with the Tamil Nadu Government funded project on 'Epidemiology of Head Injury' led him to pursue and obtain his PhD in 'Biostatistical Application in the Prediction of Outcome of Severe Head Injury' from the Tamil Nadu M G R Medical University, Chennai, India.
Within Institute of Apllied Health Sciences (IAHS), Edwin Amalraj Raja is involved in the analysis of research projects, especially statistical modelling of longitudinal data, Statistical methods in Epidemiology, etc., He is also involved in teaching and training in Medical statistics organised by the Medical Statistics Team for staff and students of this University.
Memberships and Affiliations
- Internal Memberships
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Member of School Ethics Committee
Member of Health and Safety, School of Medicine
- External Memberships
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Statistical expert for North of Scotland Research Ethics Committee (NRES)
- Research
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Research Overview
Clinical Areas of Consulting Experience
Obstetric & Gynaecology Factors associated with Maternal complications, Maternal BMI & Offspring CVD , Mortality
Infertility Classification of infertility and demographic factors affecting fertility
Maternal Obesity Offspring developing CVD
Renal disease The relationship between renal function parameters and blood pressure
common Cancers Factors contributing to time to consult GP, provider delay & stage , Mortality
Diabetes Mellitus Prevalence, risk factors, incidence of complications, patients perception of their complication
Current Research
Methodological research interests
Prediction Modelling
Categorical data analysis
Statistical methods in Epidemiology
Analysis of repeated measures / Longitudinal Data Analysis / Multilevel Modeling
Structural Equation Modelling
Cubic spline analysis - Non-linear relationship between continuous variable and outcome
Survival analysis- Competing risks- recurrent events
Supervision
Looking for a PhD student
Title: The impact of duration of freezing of IVF embryos on pregnancy and perinatal outcomes – analysis of UK national data
Background of the research proposal:
IVF (in-vitro fertilisation) is the recommended treatment for couples with unresolved infertility. It involves mixing eggs and sperm to create embryos which are then cultured in the laboratory. Usually, the best embryo is then put back in the womb, while others can be frozen for future use. The use of frozen embryos has become popular across the globe in recent years, accounting for 41% of all IVF treatments in 2019 in UK. Although many embryos are frozen for short durations, others can be kept in the freezer for many months or years and it is believed that patients can use them at any time without affecting their chances of pregnancy rates or the health of their babies.
Aim: To find an association between the duration of embryo freezing and pregnancy and perinatal outcomes among couples treated for infertility
Dataset: This study will use information of treatments undertaken between 2000 and 2019 from the Human Fertilisation Embryology Authority (HFEA) database which holds data of all IVF treatments undertaken in the UK licensed clinics, to explore the impact of the duration of embryo freezing on IVF live birth rate and safety of children.
Exposure: the duration of embryo freezing
Outcomes: The main outcome measures are live birth, gestational age (preterm vs term), birthweight (small/large for gestational age vs normal for gestational age) and congenital anomalies. The results of the proposed research will provide patients and clinicians with the necessary information so that they can make informed choices in the future.
Statistical Analyses: The student is expected to come up with appropriate statistical methods and use machine learning techniques to address the research question or objective of the study.
Funding and Grants
Murchie P, Lisa I, Raja EA, Lee AJ. Do melanoma excised in primary care have different outcomes to those excised in secondary care? Friends of ANCHOR £10,000
David M, Bhattacharya S, Abha M, Raja EA. Perinatal outcomes of singletons born following in-vitro fertilisation: a comparison of different embryo transfer strategies using UK data. NHS Grampian Endowment .(submitted)
Mairead B, Sohinee B, Andrea W, Gail F, EA Raja and Ipek. Maternal Body Mass Index in pregnancy ana cardiometabolic risk in monozygotic and dizygotic twin offspring (submitted to Wellbeing of Women)
Sohinee B, Geraldine M, Rebecca R and EA Raja. Reproductive consequences of third and fourth degree perineal tears (submitted to CHSS)
- Teaching
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Teaching Responsibilities
Teaching in the Short courses organised by Medical Statistics Team
Introduction to Medical Statistics
Intermediate Statistics Course
B medical Science SPSS practicals II
M Sc Public Health practicals
- Publications
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Page 1 of 1 Results 1 to 66 of 66
Cesarean section at full dilatation in the first birth is not associated with an increased risk of subsequent miscarriage: a historical cohort study
Acta Obstetricia et Gynecologica Scandinavica, vol. 103, no. 10, pp. 2092-2100Contributions to Journals: ArticlesInterrupted time series analysis of admissions before and after introduction of rapid review clinics in two centres
Archives of Disease in Childhood, vol. 109, no. 10, pp. 869-870Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1136/archdischild-2024-327314
- [ONLINE] View publication in Scopus
Paternal migration and child stunting in India: An analysis of NFHS-5 data.
Economic and Political Weekly, vol. 59, no. 35Contributions to Journals: ArticlesIs arrival by ambulance a risk factor for myocardial infarction in emergency department patients with cardiac sounding chest pain?
Emergency Medicine Journal, vol. 41, no. 6, pp. 376-378Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1136/emermed-2023-213643
- [ONLINE] View publication in Scopus
Symptom duration, ambulance response and emergency department transfer time in relation to development of myocardial infarction in patients with chest pain
Contributions to Conferences: PapersRisk of spontaneous preterm birth elevated after first cesarean delivery at full dilatation: a retrospective cohort study of over 30,000 women
American Journal of Obstetrics and Gynecology, vol. 230, no. 3, pp. 358.e1-358.e13Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ajog.2023.08.013
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/b258cb64-aacc-42fe-9a90-4a2d03b463ea/download
- [ONLINE] View publication in Scopus
Perinatal outcomes in singleton live births after blastocyst transfer: an analysis of 60,926 in vitro fertilization cycles from the United Kingdom
Fertility and Sterility, vol. 120, no. 2, pp. 312-320Contributions to Journals: ArticlesMaternal and perinatal outcomes of prolonged second stage of labour: a historical cohort study of over 51,000 women
BMC Pregnancy and Childbirth, vol. 23, no. 1, 467Contributions to Journals: ArticlesA comparison of perinatal outcomes following fresh blastocyst or cleavage stage embryo transfer in singletons and twins and between singleton siblings
Human Reproduction Open, vol. 2023, no. 2, hoad003Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/hropen/hoad003
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/7733d40e-680c-4965-94e8-ff58c11d895f/download
- [ONLINE] View publication in Scopus
In patients with chest pain suspicious for ACS, is arrival by ambulance associated with increased likelihood of myocardial infarction?
Royal College of Emergency Medicine Annual Scientific Conference, pp. 970Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1136/emermed-2022-RCEM2.15
Comparison of perinatal outcomes following frozen or fresh embryo transfer: separate analyses of singleton, twin and sibling live births from a linked national In vitro fertilisation registry
Fertility and Sterility, vol. 118, no. 2, pp. 323-334Contributions to Journals: ArticlesReducing asthma attacks in children using exhaled nitric oxide (RAACENO) as a biomarker to inform treatment strategy: a multicentre, parallel, randomised, controlled, phase 3 trial
The Lancet. Respiratory medicine, vol. 10, no. 6, pp. 584-592Contributions to Journals: ArticlesTreatment guided by fractional exhaled nitric oxide in addition to standard care in 6- to 15-year-olds with asthma: the RAACENO RCT
Efficacy and Mechanism Evaluation, vol. 9, no. 4Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/AWOI5587
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/56f5855f-523f-470e-b91b-5b143227048a/download
Maternal over-the-counter analgesics use during pregnancy and adverse perinatal outcomes: Cohort study of 151,141 singleton pregnancies
BMJ Open, vol. 12, no. 5, e048092Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmjopen-2020-048092
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/84895fed-18e6-421d-9549-c8eadc6cf06f/download
- [ONLINE] View publication in Scopus
Predicting personalized cumulative live birth following in vitro fertilization
Fertility and Sterility, vol. 117, no. 2, pp. 326-338Contributions to Journals: ArticlesMaternal over-the-counter analgesics use during pregnancy and adverse perinatal outcomes: cohort study of 151,141 singleton pregnancies
Human Reproduction, vol. 36, no. S1, pp. 469-469Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1093/humrep/deab130.731
The association between opening a short stay paediatric assessment unit and trends in short stay hospital admissions
BMC Health Services Research, vol. 21, no. 1, pp. 523Contributions to Journals: ArticlesDoes admission prevalence change after reconfiguration of inpatient services? An interrupted time series analysis of the impact of reconfiguration in five centres
BMC Health Services Research, vol. 21, no. 1, 75Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/s12913-021-06070-7
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/44334196-b93d-494f-96ea-5f2bbb0edd2d/download
- [ONLINE] View publication in Scopus
Family history and risk of miscarriage: a systematic review and meta-analysis of observational studies
Acta Obstetricia et Gynecologica Scandinavica, vol. 99, no. 12, pp. 1584-1594Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/aogs.13940
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/d9e849f1-0380-4ae9-a3b2-24fafab423b4/download
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Scopus
Corrigendum. Testing the twin testosterone transfer hypothesis: intergenerational analysis of 317 dizygotic twins born in Aberdeen, Scotland
Human reproduction (Oxford, England), vol. 35, no. 10, pp. 2401-2402Contributions to Journals: ArticlesTesting the twin testosterone transfer hypothesis: Intergenerational analysis of 317 dizygotic twins born in Aberdeen, Scotland
Human Reproduction, vol. 35, no. 7, pp. 1702-1710Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/humrep/deaa189
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/c00a4e8d-d7e4-4940-a48d-54029210e37b/download
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Scopus
Changing risk factors for placental abruption: a case crossover study using routinely collected data from Finland, Malta and Aberdeen
PloS ONE, vol. 15, no. 6, e0233641Contributions to Journals: ArticlesTesting the Twin Testosterone Transfer Hypothesis: Intergenerational Analysis of 317 Twins Born in Aberdeen, Scotland
67th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), pp. 288AContributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1007/s43032-020-00176-9
- [ONLINE] Springer SharedIt link
Inherited susceptibility to miscarriage: a nested case-control study of 31565 women from an intergenerational cohort
American Journal of Obstetrics and Gynecology, vol. 222, no. 2, pp. 168.e1-168.e8Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ajog.2019.08.013
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/ef52b78a-ba9b-42c0-8cb3-6527c92a3847/download
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
Weight-Based Guide Overestimates Endotracheal Tube Tip Position in Extremely Preterm Infants
American journal of perinatology, vol. 36, no. 14, pp. 1498-1503Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1055/s-0039-1678531
- [ONLINE] View publication in Mendeley
- [ONLINE] View publication in Scopus
Perinatal outcomes in singleton live births after fresh blastocyst-stage embryo transfer: a retrospective analysis of 67 147 IVF/ICSI cycles
Human Reproduction, vol. 34, no. 9, pp. 1716-1725Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/humrep/dez133
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/81ef931f-7522-4778-91d7-18b4b68a617a/download
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
Inherited predisposition to stillbirth: an intergenerational analysis of 26,788 mother-daughter pairs
American Journal of Obstetrics and Gynecology, vol. 220, no. 4, pp. 393.e1-393.e7Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ajog.2019.01.215
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/e0583e13-e1e2-4e46-85d0-f1fe374a1226/download
- [ONLINE] View publication in Scopus
Intervention thresholds and cesarean section rates: a time-trends analysis
Acta Obstetricia et Gynecologica Scandinavica, vol. 97, no. 10, pp. 1257-1266Contributions to Journals: ArticlesImpact of rurality on processes and outcomes in melanoma care: results from a whole-Scotland melanoma cohort in primary and secondary care
The British Journal of General Practice, vol. 68, no. 673, pp. 566-575Contributions to Journals: ArticlesReply: Excessive fetal growth in frozen embryo transfer: false alarm or clinical concern?
Human Reproduction Update, vol. 24, no. 4, pp. 517-518Contributions to Journals: Letters- [ONLINE] DOI: https://doi.org/10.1093/humupd/dmy011
Is frozen embryo transfer better for mothers and babies? Can cumulative meta-analysis provide a definitive answer?
Human Reproduction Update, vol. 24, no. 1, pp. 35-58Contributions to Journals: ArticlesDo patients' faces influence General Practitioners' cancer suspicions? A test of automatic processing of sociodemographic information
PloS ONE, vol. 12, no. 11, pp. 1-13Contributions to Journals: ArticlesIs initial excision of cutaneous melanoma by General Practitioners (GPs) dangerous? Comparing patient outcomes following excision of melanoma by GPs or in hospital using national datasets and meta-analysis
European Journal of Cancer, vol. 86, pp. 373-384Contributions to Journals: ArticlesGestational age at delivery of twins and perinatal outcomes, a Scottish cohort study
British Maternal & Fetal Medicine Society (BMFMS) 19th Annual Conference 2017, pp. 145-145Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1111/1471-0528.14589
Obstetric and perinatal outcomes after either fresh or thawed frozen embryo transfer: an analysis of 112,432 singleton pregnancies recorded in the Human Fertilisation and Embryology Authority anonymized dataset
Fertility and Sterility, vol. 106, no. 7, pp. 1703-1708Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.fertnstert.2016.08.047
Maternal gestational weight gain and offspring's risk of cardiovascular disease and mortality
Heart, vol. 102, no. 18, pp. 1456-1463Contributions to Journals: ArticlesEffect of longer health service provider delays on stage at diagnosis and mortality in symptomatic breast cancer
Breast, vol. 24, no. 3, pp. 248-255Contributions to Journals: ArticlesMaternal Obesity During Pregnancy Associates With Premature Mortality and Major Cardiovascular Events in Later Life
Hypertension, vol. 66, no. 5, pp. 938-944Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1161/HYPERTENSIONAHA.115.05920
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/f02ea106-2693-42ca-b3b4-1d7be167f8b3/download
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/6c585f65-00a9-4878-a4c8-96d5b3f5d079/download
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/2910b6bf-f5b0-48d1-b9a1-c648a7250a39/download
Time from first presentation in primary care to treatment of symptomatic colorectal cancer: effect on disease stage and survival
British Journal of Cancer, vol. 111, no. 3, pp. 461-469Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/bjc.2014.352
Authors' response to Diagnostic biopsy of melanoma: primary or secondary care?: Mortality and morbidity after initial diagnostic excision biopsy of cutaneous melanoma in primary versus secondary care
The British Journal of General Practice, vol. 64, no. 618, pp. 14Contributions to Journals: Comments and Debates- [ONLINE] DOI: https://doi.org/10.3399/bjgp14X676311
Association between maternal body mass index during pregnancy, short-term morbidity and increased health service costs: a population based study
BJOG-An International Journal of Obstetrics and Gynaecology, vol. 121, no. 1, pp. 72-82Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/1471-0528.12443
Maternal and perinatal consequences of antepartum haemorrhage of unknown origin
BJOG-An International Journal of Obstetrics and Gynaecology, vol. 121, no. 1, pp. 44-52Contributions to Journals: ArticlesPrevalence and year-on-year trends in childhood thinness in a whole population study
Archives of Disease in Childhood, vol. 99, no. 1, pp. 58-61Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/archdischild-2013-304423
Maternal obesity during pregnancy and premature mortality from cardiovascular event in adult offspring: follow-up of 1 323 275 person years
British Medical Journal, vol. 347, no. -, f4539Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.f4539
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/3e9dff78-f3e2-4994-b2ef-800de8b82dc7/download
Growing up before growing out: secular trends in height, weight and obesity in 5–6-year-old children born between 1970 and 2006
Archives of Disease in Childhood, vol. 98, no. 4, pp. 269-273Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/archdischild-2012-302391
Pregnancy outcomes of women with and without a history of anorexia nervosa
Psychological Medicine, vol. 42, no. 12, pp. 2651-2660Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0033291712000414
Outcomes following hysterectomy or endometrial ablation for heavy menstrual bleeding: retrospective analysis of hospital episode statistics in Scotland reply
British Journal of Obstetrics and Gynaecology, vol. 119, no. 3, pp. 375Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1471-0528.2011.03236.x
Reproductive outcomes following induced abortion: a national register-based cohort study in Scotland
BMJ Open, vol. 2, e000911Contributions to Journals: ArticlesOutcomes following hysterectomy or endometrial ablation for heavy menstrual bleeding: retrospective analysis of hospital episode statistics in Scotland
BJOG-An International Journal of Obstetrics and Gynaecology, vol. 118, no. 10, pp. 1171-1179Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1471-0528.2011.03237.x
- [ONLINE] View publication in Scopus
Skilled care at birth among rural women in Nepal: practice and challenges
The Journal of Health, Population and Nutrition, vol. 29, no. 4, pp. 371-378Contributions to Journals: ArticlesKnowledge, attitude, and prevalence of overweight and obesity among civil servants in Nepal
Asia-Pacific Journal of Public Health, vol. 23, no. 4, pp. 507-517Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1177/1010539509348662
Inherited predisposition to spontaneous preterm delivery
Obstetrics & Gynecology, vol. 115, no. 6, pp. 1125-1133Contributions to Journals: ArticlesPatient satisfaction with GP-led melanoma follow-up: a randomised controlled trial
British Journal of Cancer, vol. 102, no. 10, pp. 1447-1455Contributions to Journals: Articles- [ONLINE] https://www.nature.com/articles/6605638
- [ONLINE] DOI: https://doi.org/10.1038/sj.bjc.6605638
- [ONLINE] https://pubmed.ncbi.nlm.nih.gov/20461089/
Seeing other women breastfeed: how vicarious experience relates to breastfeeding intention and behaviour
Maternal and Child Nutrition, vol. 6, no. 2, pp. 134-146Contributions to Journals: ArticlesThe Epidemiology of infertility in the North East of Scotland.
Human Reproduction, vol. 24, no. 12, pp. 3096-3107Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1093/humrep/dep287
Factors contributing to the time taken to consult with symptoms of lung cancer: a cross-sectional study
Thorax, vol. 64, no. 6, pp. 523-531Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/thx.2008.096560
Prevalence of Obesity in South Asians living in the UK.
Contributions to Conferences: PapersHealth and lifestyle of Nepalese migrants in the UK
BMC International Health and Human Rights, vol. 8, 6Contributions to Journals: ArticlesUtilisation of postnatal care among rural women in Nepal
BMC Pregnancy and Childbirth, vol. 3, no. 7, 19Contributions to Journals: ArticlesCost of Epilepsy Treatment in a State Government Hospital A Preliminary Study
Annals of Indian Academy o Neurology, vol. 6, no. 2, pp. 7-10Contributions to Journals: ArticlesTreatment-seeking behavior and compliance of diabetic patients in a rural area of south India
Ann N Y Acad Sci, vol. 958, no. 1, pp. 420-424Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/j.1749-6632.2002.tb03017.x
- [ONLINE] https://pubmed.ncbi.nlm.nih.gov/12021154/
Marriage, monogamy and HIV: a profile of HIV-infected women in south India
International Journal of STD & AIDS, vol. 11, no. 4, pp. 250-253Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1258/0956462001915796
- [ONLINE] https://pubmed.ncbi.nlm.nih.gov/10772089/
Attitudes of health care professionals towards organ donation
Indian Journal of Urology, vol. 16, no. 2, pp. 98-105Contributions to Journals: ArticlesPrevalence and risk factors of HIV-1 AND HIV-2 infection in urban and rural areas of Tamilnadu, India
International Journal of STD & AIDS, vol. 9, no. 2, pp. 98-103Contributions to Journals: ArticlesCLINICAL CHARACTERISATION OF PERSONS WITH HIV AND TUBERCULOSIS IN SOUTH INDIA
AIDS, vol. 10, pp. S41Contributions to Journals: ArticlesSpectrum of opportunistic infections among AIDS patients in Tamil Nadu, India
International Journal of STD & AIDS, vol. 6, no. 6, pp. 447-9Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1177/095646249500600615
- [ONLINE] https://pubmed.ncbi.nlm.nih.gov/8845406/