Senior Research Fellow
- Email Address
- Telephone Number
- +44 (0)1224 438123
- Office Address
Academic Urology Unit Health Sciences Building (2nd Floor) University of Aberdeen Foresterhill Aberdeen AB25 2ZD Tel: +44 (0)1224 559086 Fax: +44 (0)1224 554580 Email: email@example.com
- School of Medicine, Medical Sciences and Nutrition
Steven is a Research Fellow in the Academic Urology Unit at the University of Aberdeen. His research themes cover the broad spectrum of evidence-based medicine in urology. This encompasses assessing the effectiveness of treatments in clinical trials, developing core outcome sets, providing critical reviews of the evidence base, creating evidence-based (or where necessary consensus-based) clinical practice guidelines, and implementing guideline recommendations in clinical practice. Steven is a member of the European Association of Urology (EAU) methodology committee which oversees the quality of the EAU’s systematic review and clinical practice guideline programme and delivers training on core evidence-based medicine skills in systematic reviews and guideline production. He is also a founding member of the IMpact Assessment of Guidelines Implementation and Education (IMAGINE) group which aims to assess current variations in practice, investigate barriers and facilitators to guideline adherent practice, and improve adherence to strong, high level of evidence, guideline recommendations. Prostate Cancer DIagnOsis and TreatmeNt Enhancement through the Power of Big Data in EuRope (PIONEER) is one of Steven’s recent projects, where his heaviest involvement is in the work to help standardise outcome definitions across all stages of disease to support the Big Data analysis work and improve the consistency of outcome reporting, outcome definition and measurement in future clinical trials and clinical audit.
- PhD Sociology2010 - University of Edinburgh
- MRes Social Research Methods2006 - University of Aberdeen
- BA (Hons.) Applied Social Science2005 - The Robert Gordon University
An overview of current projects:
Core Outcome Set Development Projects
Renal Cancer Core Outcome Sets (R-COS)
In this project, part funded by the Arcobaleno Cancer Trust and NHS Grampian Endowments, we are developing three seperate Core Outcome Sets (COS) for localised, locally advanced, and metastatic stages of kidney cancer. This includes two systematic reviews, an interview study and three Delphi studies. The COMET registration, giving full study details is accessible here: https://www.comet-initiative.org/studies/details/1406
Bladder Cancer Core Outcome Sets (B-COS)
In this project, we are developing Core Outcome Sets for the various stages of bladder cancer. Forming the initial statge of the project, we published an article reviewing outcome reporting heterogeneity in non-muscle invasive bladder cancer - accessible here: https://content.iospress.com/articles/bladder-cancer/blc201510
The COMET registration, giving full study details is availabe here: https://www.comet-initiative.org/studies/details/1135
Prostate Cancer Core Outcome Sets
We devleoped a COS for localised prostate cancer. The results can be accessed here: https://bjui-journals.onlinelibrary.wiley.com/doi/abs/10.1111/bju.13854
Our prostate cancer COS work was subsequently updated and incorporated in the PIONEER project. More detail about PIONEER can be viewed here: https://prostate-pioneer.eu/
Implementation Science Projects
IMAGINE (IMpact Assessment of Guidelines Implementation and Education)
IMAGINE is a European Association of Urology (EAU) working group focussing on mapping adherence to EAU guidelines and, where variation or suboptimal practice is identified, investigating the barriers and facilitators to guideline adherence, and developing implementation interventions to adress the barriers and leverage the facilitators. You can read more about the IMAGINE group in this editorial
RESECT (Transurethral REsection and Single instillation intra-vesical chemotherapy Evaluation in bladder Cancer Treatment (RESECT) Improving quality in TURBT surgery.)
RESECT is a collaborative project with the British Urology Researchers in Surgical Training (BURST) group, including researchers from the Academic Urology Unit and HSRU. A main aim of RESECT is to test intereventions aimed at improving adherence to guidelines around single instilation of chemotherapy adn documentation of the procudure - which have been shown to be associated with improved patient outcomes. You can read more about RESECT here: https://www.bursturology.com/Studies/Resect/Overview/
OPTIMA (OPtimal Treatment for patients wiht solid tumours in Europe through Artificial Intelligence)
OPTIMA is a 34 partners-based IMI project. The programme aim is to design, develop and deliver the first interoperable and GDPR-compliant European real-world oncology data and evidence generation platform based on the needs of the clinicians and patients, in an inclusive and sustainable way. It will be built on a combination of federated and centralised access to a vast network of European data providers to help answer the highest priority research questions in prostate, breast and lung cancer, especially where current existing evidence underpinning clinical practice guidelines is weak. In parallel, comprehensive decision support toolsets based on national and international guidelines with approved regular updates of guideline recommendations underpinned by evidence from advanced statistical analysis and AI will be made available to fill the guidelines gaps and better support shared decision making by clinicians and patients.
There is evidence to suggest that Androgen Deprivation Therapy (ADT) is overused in men with localised prostate cancer. it is unclear why, and it is unclear what the best strategies for deimplementing ADT are. This reserach problem is the focus of Jennifer Dunsmore's PhD project, which Steven is supervising. You can read more about Jennifer and her reserach here: https://www.abdn.ac.uk/iahs/research/urology/metis/profiles/j.dunsmore.19
Guideline Development Projects
Steven sits on the European Association of Urology (EAU) Guidelines Office Methodology Committee. This committee oversees the training of Guidelines Associates through Systematic Review workshops.
EVOLVE (giving patients a meaningful voice in the design and delivery of care)
EVOLVE is a unique collaboration of a profession society (European Association of Urology), guideline panels, researchers, clinicians and patient representatives to improve guideline development and implementation for genitourinary cancers in Europe. The aim of the project is to develop a model of patient involvement that will give patients a meaningful voice in the design and delivery of care and will investigate how wider stakeholders can help to integrate the patient voice into guidelines. You can read more about EVOLVE here: https://www.abdn.ac.uk/iahs/research/urology/metis/evolve-1618.php
Steven contributes to the design, delivery and assessment of the MSc. level courses in the Institute of Applied Health Sciences linked above. He also supervises MSc. dissertations and often supervises medical student summer placements in the Aberdeen Summer Research Scholarship (ASRS) programme.
Steven currently supervises two PhD. projects and is intersted in supervising any project aligning with his broad interests in the desing and delivery of urology health services.
Non-course Teaching Responsibilities
Alongside formal teaching at the University of Aberdeen, Steven and his colleagues also developed a 2.5 day course for the European Association of Urology (EAU) on systematic reviews for clinical practice guidelines.
Steven also teaches the systematic review element for the European Organisaiton for Research and Treatment of Cancer (EORTC) 'clinical trial statistics for non-statisticians' course. https://event.eortc.org/stats2021/
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The EANM Focus 5 consensus on 'molecular imaging and theranostics in prostate cancer': the future begins todayEuropean Journal of Nuclear Medicine and Molecular ImagingContributions to Journals: Editorials
Survivorship data in Prostate Cancer: Where are we and where do we need to be?European Urology Open Science, vol. 59, pp. 27-29Contributions to Journals: Comments and Debates
Reply to Badar M. Mian. Prostate Biopsy: Hyperbole and Misrepresentation Versus Scientific Evidence and Equipoise. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2023.05.039European UrologyContributions to Journals: Editorials
European Association of Nuclear Medicine Focus 5: Consensus on Molecular Imaging and Theranostics in Prostate CancerEuropean UrologyContributions to Journals: Articles
Effectiveness of de-implementation strategies for low-value prescribing in secondary care: a systematic reviewImplementation Science Communications, vol. 4, 115Contributions to Journals: Articles
A protocol for the development of Core Outcome Sets for effectiveness trials and clinical audits in Renal Cell Cancer (R-COS)BJU International, vol. 4, no. 5, pp. 504-512Contributions to Journals: Articles
En bloc resection of bladder tumour: the rebirth of past through reminiscenceWorld Journal of Urology, vol. 41, no. 10, pp. 2599-2606Contributions to Journals: Review articles
The need for core outcome sets in renal cancer clinical effectiveness researchMini-invasive Surgery, vol. 7, 23Contributions to Journals: Editorials
Audit, Feedback, and Education to Improve Quality and Outcomes in Transurethral Resection and Single-Instillation Intravesical Chemotherapy for Nonmuscle Invasive Bladder Cancer Treatment: Protocol for a Multicenter International Observational Study With an Embedded Cluster Randomized TrialJMIR Research Protocols, vol. 12, e42254Contributions to Journals: Articles
Assessing the quality of patient-reported outcome measurements for gynecological cancers: a systematic reviewFuture Oncology, vol. 19, no. 9, pp. 663-678Contributions to Journals: Review articles