Advanced Research Fellow
- About
-
- Email Address
- renato.santos@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438577
- Office Address
Liberty Building, Room GD07
Foresterhill Road
AB25 2ZP
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I obtained the BSc in Biology in 2008, and the Doctorate degree (Cell Biology) in 2014 from the Faculty of Sciences and Technology, University of Coimbra, Portugal. My work was focused on numerous aspects of cellular and, particularly, mitochondrial biology, namely, mitochondrial biogenesis, mitochondrial fission and fusion and also autophagy/mitophagy. The main subject of my work was to understand the relation between diabetes and the propensity do develop dementia, particularly Alzheimer's disease. In 2017, I joined the team of Dr. Charles Harrington at the Institute of Medical Sciences, University of Aberdeen. My research interests include the understanding of neuropathological processes, uncovering of therapeutic targets and study of efficient therapeutic approaches to tackle progression of neurodegenerative diseases.
Qualifications
- BSc Biology2008 - University of Coimbra, Portugal
- PhD Cell Biology2014 - University of Coimbra, Portugal
Internal Memberships
03/2023-02/2025: Board Member - School Ethics Review Board (SERB), for the School of Medicine, Medical Sciences and Nutrition
Latest Publications
Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain
FEBS Journal, vol. 292, no. 10, pp. 2602-2623Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/febs.70021
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/372a1f89-dc2a-4be5-a64e-19083dc6d8d6/download
- [ONLINE] View publication in Scopus
Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice
International Journal of Molecular Sciences, vol. 24, no. 13, 10810Contributions to Journals: ArticlesHMTM-Mediated Enhancement of Brain Bioenergetics in a Mouse Tauopathy Model Is Blocked by Chronic Administration of Rivastigmine
Biomedicines, vol. 10, no. 4, 867Contributions to Journals: ArticlesMechanisms of anticholinesterase interference with tau aggregation inhibitor activity in a tau-transgenic mouse model
Current Alzheimer Research, vol. 17, no. 3, pp. 285-296Contributions to Journals: ArticlesMiddle-Aged Diabetic Females and Males Present Distinct Susceptibility to Alzheimer Disease-like Pathology
Molecular Neurobiology, vol. 54, no. 8, pp. 6471-6489Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s12035-016-0155-1
- Research
-
Research Overview
Neurodegeneration
Alzheimer's disease
Tau protein
Mitochondria
Oxidative Stress
Autophagy/Mitophagy
Therapeutics
