Personal Chair
- About
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- Email Address
- m.romano@abdn.ac.uk
- Telephone Number
- +44 (0)1224 272507
- Office Address
- Office 337, Institute for Complex Systems and Mathematical Biology, Department of Physics, Meston Building, Old Aberdeen Office 3:47, Institute of Medical Sciences, Foresterhill
- School/Department
- School of Natural and Computing Sciences
- Research
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Research Overview
I am interested in the understanding of fundamental biological processes using theoretical approaches based on nonlinear dynamics and statistical physics and combining them with experimental data. In particular, I am interested in the process of translation or synthesis of proteins, the coupling between transcription and translation, how ribosomes, the molecular machines that manufacture proteins, are synthesised, and its relationship to the cell cycle. I am furthermore interested in the effect of combinatorial stresses in yeast, as well as the effects of different types of stress on the cell cycle.
In addition to these biological questions, I have a growing interest in the application of data science methods across disciplines, such as healthcare and the energy sector. I am particularly interested in how data-driven approaches can be used to analyse complex systems, uncover patterns, and inform decision-making in these domains.
Funding and Grants
SULSA studentship (modeling of translation)/ SABR grant (Combinatorial Responses In Stress Pathways)/BBSRC grant (Ribosome Traffic Flow on the mRNA as a Regulator of Cellular Protein Production)
- Teaching
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Teaching Responsibilities
Electromagnetism (PX3008, 3rd year Physics) and Introduction to Mathematics and Modelling of Biological Systems (SB5005, MSc in Cell and Molecular Systems Biology)
- Publications
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Page 3 of 8 Results 21 to 30 of 75
The wiper model: avalanche dynamics in an exclusion process
Journal of statistical mechanics-Theory and experiment, vol. 2013, 10015Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1088/1742-5468/2013/10/P10015
From START to FINISH: the influence of osmotic stress on the cell cycle
PloS ONE, vol. 8, no. 7, e68067Contributions to Journals: ArticlesDominant-negative release factors and their effect on termination and translational recoding events
Translation UK 2013Contributions to Conferences: PostersRibosome traffic on mRNAs maps to gene ontology: genome-wide quantification of translation initiation rates and polysome size regulation
PLoS Computational Biology , vol. 9, no. 1, e1002866Contributions to Journals: ArticlesA yeast tRNA mutant that causes pseudohyphal growth exhibits reduced rates of CAG codon translation
Molecular Microbiology, vol. 87, no. 2, pp. 284–300Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1111/mmi.12096
Transport on a lattice with dynamical defects
Physical Review. E, Statistical, Nonlinear and Soft Matter Physics, vol. 87, no. 1, 012705Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1103/PhysRevE.87.012705
Combinatorial stresses kill pathogenic Candida species
Medical Mycology, vol. 50, no. 7, pp. 699-709Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3109/13693786.2012.672770
A max-plus model of ribosome dynamics during mRNA translation
Journal of Theoretical Biology, vol. 303, no. -, pp. 128-140Contributions to Journals: Articles- [ONLINE] http://arxiv.org/abs/1105.3580v1
- [ONLINE] DOI: https://doi.org/10.1016/j.jtbi.2012.03.007
Impact of combinatorial stresses upon Candida albicans
Mycoses, vol. 55, no. Suppl. 4, pp. 15Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1111/j.1439-0507.2012.02204.x
- [ONLINE] View publication in Scopus
A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungi
BMC Research Notes, vol. 5, 258Contributions to Journals: Articles