BSc (Hons), PhD
Senior Trial Manager
- About
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- Email Address
- l.constable@abdn.ac.uk
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I am a Senior Trials Manager working across the portfolio of clinical trials at the Centre for Healthcare Randomised Trials (CHaRT) clinical trials unit (CTU) within the Aberdeen Centre for Evaluation (ACE, formerly Health Services Research Unit (HSRU)).
I have worked as the lead trial manager on the CHESS, PIP, DIAMOND, CATHETER II, VUE, MASTER and ASICA trials.
I graduated with a BSc in Biosciences and Chemistry and a PhD in Cancer cell and Molecular biology. Prior to joining the unit, I worked as a Research Fellow at Aberdeen University on a range of projects with an emphasis on cancer biomarkers.
External Memberships
Member of the Executive Committee of the UK Trial Managers Network (UKTMN)
Member of the Education Committee for the Society for Clinical Trials (2013 - 2020)
Chair of the Education Committee for the Society for Clinical Trials (2018-2019)
Co-Chair of the Education Committee for the Society for Clinical Trials (2017-2018)
Chair of the Webinar Committee for the Society for Clinical Trials (2017-2018)
Member of the Board of Directors for the Society for Clinical Trials (2016)
Latest Publications
Supporting the professional development of trial managers: how can you help?
Trials, vol. 26, no. 1, 436Contributions to Journals: ArticlesProtocol for a feasibility randomized control trial of the Supporting Toddlers with a connection to autism or ADHD to develop Strong Attention, Regulation, and Thinking skills (START) programme
Pilot and Feasibility Studies, vol. 11, no. 1, 122Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/s40814-025-01697-3
CATHETER II, a Randomised Controlled Trial Comparing the Clinical and Cost Effectiveness of Various Washout Policies versus No Washout Policy in Preventing Catheter Associated Complications in Adults Living with Long Term Catheters
45th Congress of the Société Internationale d'UrologieContributions to Conferences: PostersPatients and health care professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: Qualitative Study of the CATHETER II Trial
BMJ Open, vol. 15, no. 4, e087206Contributions to Journals: ArticlesCATHETER II, a randomised controlled trial comparing the clinical and cost effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long term catheters
European Association of Urology Annual Congress 2025, pp. A0090Contributions to Conferences: Abstracts- [ONLINE] http://300500960
- Research
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Research Overview
Clinical trials methodology
Clinical trial management
Research Areas
Applied Health Sciences
Current Research
VUE Trial: Vault or Uterine prolapse surgery evaluation: Two parallel randomised controlled trials of surgical options for upper compartment (vault or uterine) pelvic organ prolapse.
MASTER Trial: investigating the surgical treatment of male stress incontinence after prostate surgery.
ASICA: Achieving Self-Directed Integrated Cancer Aftercare (ASICA) in melanoma: A randomised patient-focused trial of delivering the ASICA intervention as a means to earlier detection of recurrent and second primary melanoma
CATHETER II Trial: evaluating the effect of weekly saline or acidic prophylactic catheter washout policies with standard care on catheter related complications.
- Teaching
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Teaching Responsibilities
I have supervised a number of BSc and MSc student research projects, including topics such as understanding patient's decision making to participate in clinical trials; rapid introduction of new cancer therapies; personalised cancer therapies; and investigation of the mode of action novel cancer therapeutics.
- Publications
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Page 2 of 4 Results 11 to 20 of 35
Male sling is as good as more complex surgery for incontinence after prostate surgery
BMJ (Clinical research ed.), vol. 381, pp. 1179Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1136/bmj.p1179
User Experiences of a Digital Intervention to Support Total-Skin-Self-Examination by Melanoma Survivors: Nested Qualitative Evaluation Embedded in a Randomized Controlled Trial
JMIR Dermatology, vol. 6, e39544Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.2196/39544
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/89888970-6728-4447-9b24-ebf23992909d/download
- [ONLINE] View publication in Scopus
Randomised controlled trial comparing the clinical and cost-effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long-term catheters: study protocol for the CATHETER II study
Trials, vol. 23, no. 1, 630Contributions to Journals: ArticlesThe Achieving Self-directed Integrated Cancer Aftercare Intervention for Detection of Recurrent and Second Primary Melanoma in Survivors of Melanoma: Pilot Randomized Controlled Trial
JMIR cancer, vol. 8, no. 3, e37539Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.2196/37539
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/c6f51a95-1926-4a98-9b8d-61fb63aabd86/download
Synthetic sling or artificial urinary sphincter for men with urodynamic stress incontinence after prostate surgery: the MASTER non-inferiority RCT
Health Technology Assessment, vol. 26, no. 36, 184Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.3310/TBFZ0277
Achieving Integrated Self-Directed Cancer Aftercare (ASICA) for melanoma: How a digital intervention to support total skin self-examination was used by people treated for cutaneous melanoma
BMC Cancer, vol. 21, 1217Contributions to Journals: ArticlesOutcomes of a non-inferiority randomised controlled trial of surgery for men with urodynamic stress incontinence after prostate surgery (MASTER)
European Urology, vol. 79, no. 6, pp. 812-823Contributions to Journals: ArticlesProviding trial results to participants in Phase III pragmatic effectiveness RCTs: a scoping review
Trials, vol. 22, 361Contributions to Journals: ArticlesIt is unprecedented: trial management during the COVID-19 pandemic and beyond
Trials, vol. 21, pp. 784Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/s13063-020-04711-6
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/e8e74297-fabd-479d-8049-4556fab01909/download
- [ONLINE] View publication in Scopus
How to Deal with a Temporary Suspension and Restarting Your Trial: Our Experiences and lessons Learnt
Trials, vol. 21, no. 1, pp. 765Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1186/s13063-020-04705-4
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/544f2809-ed3f-47b7-8aee-b5532ca43066/download
- [ONLINE] View publication in Scopus