Research Technician
- About
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- Email Address
- gary.duncan@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438669
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Gary has over 25 years of Mass Spectrometry experience. He started work at what was then the Rowett Research Institute in 1986, and after six weeks training in analytical techniques, started working in the Gas Isotope Ratio Mass Spectrometry (GIRMS) laboratory assisting Dr Brian McGaw and Mr Eric Milne. As interest in this technique grew, the lab eventually had four mass spectrometers dedicated to analysing the stable isotopes of Carbon, Hydrogen and Oxygen from a variety of biological sources, supporting research into energy expenditure and protein synthesis. The research programmes of the Rowett then required Liquid Chromatography Mass Spectrometry (LC/MS) and a MAT 900 double-sector LC-MS/MS system was purchased in 1998, along with a LaserMAT MALDI mass spectrometer. Initially his role was to develop techniques for sample analysis on the MALDI, but soon took over the role of managing the LC/MS mass facility. This coincided with a ‘take-off’ in the popularity of using LCMSMS in sample analysis, firstly in the growth of identifying proteins separated on 2D gels and more recently the targeted quantitation analysis of small molecules. The main areas of analysis are in the quantification of Polyphenols relating to dietary consumption and human health and the quantification of Mycotoxins in foods and crops, in particular, the detoxification of Deoxynivalenol. The LCMSMS facility now has four mass spectrometers, with access to an ion trap to support work in these areas of research.
Other Areas of interest include:
- Vitamin D3
- Methylamines
- Anthocyanins
- Nicotinamides
- Carboxymethyl Lysines
- Antibiotics
Latest Publications
Efficacy of pre-treatment of insoluble fibres derived from persimmon (Diospyros kaki) fruit by-products to promote growth of beneficial human colonic bacteria
Food Bioscience, vol. 68, 106737Contributions to Journals: ArticlesHemp Seed-Based Foods and Processing By-Products Are Sustainable Rich Sources of Nutrients and Plant Metabolites Supporting Dietary Biodiversity, Health, and Nutritional Needs
Foods, vol. 14, no. 5, 875Contributions to Journals: ArticlesSegmental analysis of human hair reveals intra-annual variation in 25(OH)D3 concentrations in modern and archaeological individuals
Scientific Reports, vol. 15, 3078Contributions to Journals: ArticlesFava bean and buckwheat are sustainable food sources which support satiety and beneficially modulate several biomarkers, bacteria and metabolites associated with human health
European Journal of Nutrition, vol. 64, 211Contributions to Journals: ArticlesPersimmon Fiber-Rich Ingredients Promote Anti-Inflammatory Responses and the Growth of Beneficial Anti-Inflammatory Firmicutes Species from the Human Colon
Nutrients, vol. 16, no. 15, 2518Contributions to Journals: Articles
- Publications
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Page 5 of 7 Results 41 to 50 of 64
Impact of Obesity and Leptin on Protein Expression Profiles in Mouse Colon
Digestive Diseases and Sciences, vol. 56, no. 4, pp. 1028-1036Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s10620-010-1394-z
Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation
Journal of Proteome Research, vol. 9, no. 4, pp. 1941-1950Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1021/pr901103n
Intervention with fish oil, but not with docosahexaenoic acid, results in lower levels of hepatic soluble epoxide hydrolase with time in apoE knockout mice
British Journal of Nutrition, vol. 103, no. 1, pp. 16-24Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0007114509991450
Maternal diets deficient in folic acid and related methyl donors modify mechanisms associated with lipid metabolism in the fetal liver of the rat
British Journal of Nutrition, vol. 102, no. 10, pp. 1445-1452Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1017/S0007114509990389
Balancing Inflammatory, Lipid, and Xenobiotic Signaling Pathways by VSL#3, a Biotherapeutic Agent, in the Treatment of Inflammatory Bowel Disease
Inflammatory Bowel Diseases, vol. 15, no. 11, pp. 1721-1736Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/ibd.20999
Gene and protein expression profiles in the foetal liver of the pregnant rat fed a low protein diet
Genes & Nutrition, vol. 4, no. 3, pp. 189-194Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1007/s12263-009-0125-6
Phenolic acid content of fruits commonly consumed and locally produced in Scotland
Food Chemistry, vol. 115, no. 1, pp. 100-104Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.foodchem.2008.11.086
Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet
Proteomics, vol. 9, no. 12, pp. 3244-3256Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/pmic.200800761
The response of human colonocytes to folate deficiency in vitro: functional and proteomic analyses
Journal of Proteome Research, vol. 7, no. 8, pp. 3254-3266Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1021/pr700751y
Aorta protein networks in marginal and acute zinc deficiency
Proteomics, vol. 8, no. 10, pp. 2126-2135Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1002/pmic.200700784