Dr Elzbieta Krol
MSc (Jagiellonian University, Poland); PhD (Jagiellonian University, Poland)
My research interests focus on whole animal energetics and physiology. This framework provides the common theme that links my interests in the role of energy use during both reproduction and the development of obesity.
My doctoral work on the energetics of hedgehogs (Jagiellonian University, Poland) and postdoctoral work on reproduction in laboratory mice (University of Aberdeen, Scotland) and deer mice (University of California, Riverside, USA) have resulted in a novel hypothesis that the limits to sustained energy intake at peak lactation are imposed by the capacity of the animal to dissipate body heat. This hypothesis is currently under further investigation.
My obesity related work focuses on the effects of photoperiod on body mass, food intake, body composition, energy balance and hypothalamic gene expression in the field vole, which provides a new animal model for the investigation of seasonal adiposity at both organism and molecular levels. The major finding of this project is that the photoperiod-induced increase in body mass is associated with the up-regulation of the suppressor of cytokine signalling (SOCS3). This appears to act as a desensitisation mechanism that allows animals to ignore elevated leptin levels generated by increased adiposity, leading to an accumulation of body fat without counter-regulatory mechanisms.
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Gill Transcriptomic Responses to Toxin-producing Alga Prymnesium parvum in Rainbow TroutFrontiers in Immunology, vol. 12, 794593Contributions to Journals: Articles
Determinants of heart rate in Svalbard reindeer reveal mechanisms of seasonal energy managementPhilosophical Transactions of the Royal Society B: Biological Sciences, vol. 376, no. 1831, 20200215Contributions to Journals: Articles
Fat storage influences fasting endurance more than body size in an ungulateFunctional Ecology, vol. 35, no. 7, pp. 1470-1480Contributions to Journals: Articles
Integration of Transcriptome, Gross Morphology and Histopathology in the Gill of Sea Farmed Atlantic Salmon (Salmo salar): Lessons from Multi-site SamplingFrontiers in Genetics, vol. 11, 610Contributions to Journals: Articles
Photoperiodic regulation in a wild-derived mouse strainJournal of Experimental Biology, vol. 223, no. 6, jeb217687Contributions to Journals: Articles
From gross morphology to gill transcriptome in farmed Atlantic salmon (Salmo salar): Lessons from multi-site samplingFish & Shellfish Immunology, vol. 91, pp. 467Contributions to Journals: Abstracts
Impact of sea lice (Caligus rogercresseyi) infection levels on skin transcriptome in Atlantic salmon (Salmo salar)Fish & Shellfish Immunology, vol. 91, pp. 436-437Contributions to Journals: Abstracts
Switching off the furnace: brown adipose tissue and lactationMolecular Aspects of Medicine, vol. 68, pp. 18-41Contributions to Journals: Articles
Limits to sustained energy intake XXVIII: Beneficial effects of high dietary fat on lactation performance in miceJournal of Experimental Biology, vol. 221, jeb180828Contributions to Journals: Articles
Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivoMolecular Metabolism, vol. 6, no. 10, pp. 1198-1211Contributions to Journals: Articles