PhD, AFHEA
Advanced Research Fellow
- About
-
- Email Address
- c.s.whyte@abdn.ac.uk
- Telephone Number
- +44 (0)1224 437897
- Office Address
Lab 1.33 Office 3.47:6
Institute of Medical Sciences
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I am an Advanced Research Fellow at the Aberdeen Cardiovascular and Diabetes Centre, Institute of Medical Science. I obtained my PhD in Medical Sciences at Rowett Research Institute of Nutrition and Health through the University of Aberdeen. My research to date has focused on cellular regulation of fibrinolysis with a particular interest in the role of platelets in directing this process. I have also investigated fibrinolytic dysregulation in disease situations including COVID-19, DVT and stroke. I was the first recipient of Friends of Anchor's Transition to Independence Fellowship and I am currently funded by the British Heart Foundation to investigate dysregulated fibrinolysis in cancer associated thrombosis.
Qualifications
- PhD Medical Sciences2009 - University of Aberdeen
Memberships and Affiliations
- Internal Memberships
-
University Research Committee - ECR Representative
Nvision Researcher Development Network Committee
Postdoctoral Research Committee - Institute of Medical Sciences Representative
School of Medicine, Medical Sciences & Nutrition Health and Safety Committee - ECR Representative
- External Memberships
-
British Society for Haemostasis and Thrombosis Committee
Vice-Chair - International Society for Fibrinolysis and Proteolysis
Membership Committee - International Society on Thrombosis and Haemostasis
Latest Publications
Colchicine acutely reduces liver-secreted inflammatory and metabolic proteins in blood
European Journal of Pharmacology, 178725Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ejphar.2026.178725
Cancer-Associated Thrombosis (CAT); mechanisms and treatment options
Thrombosis Journal, vol. 23, no. 1, 116Contributions to Journals: ArticlesEndothelial cell source dictates the expression and release of fibrinolytic markers in a proinflammatory environment
Research and Practice in Thrombosis and Haemostasis, vol. 9, no. 5, 102929Contributions to Journals: ArticlesAcute obstetric coagulopathy is associated with excess plasmin generation and proteolysis of fibrinogen and factor V
Blood Advances, vol. 9, no. 11, pp. 2751-2762Contributions to Journals: ArticlesActivated platelets retain and protect most of their factor XIII-A cargo from proteolytic activation and degradation
Blood Advances, vol. 8, no. 19, pp. 5072–5085.Contributions to Journals: Articles
Prizes and Awards
D. Collen Young Investigator Award runner up 2023
D. Collen Young Investigator Award runner up 2018
- Research
-
Supervision
Previous PhD students (second supervisor):
Dr Joanne Mitchell
Dr Gael Morrow
Dr Fahad Alshehri
Dr Steven Humphreys
Funding and Grants
Current Funding as Principal Investigator:
Defining the role of fibrinolytic dysregulation in breast cancer associated thrombosis. The British Heart Foundation. Co-Investigators Prof Valerie Speirs and Prof Nicola Mutch.
Current Funding as Co-Investigator:
Bleeding after childbirth – exploring abnormal blood clotting and how to treat it. Chief Scientist Office. PI: Prof Nicola J Mutch. Co-I Dr Mairead Black, Dr Lucy De Lloyd, Prof Peter Collins, Dr Sarah Bell.
Arterial Thrombosis In Type II Diabetes: A Role For Impaired Fibrinolysis. Medical Research Scotland. PI: Prof Nicola J Mutch. Co-I Dr Dana Huskens.
Targeting impaired Fibrinolysis in Acute Coronary Syndrome: A Path to Better Treatment. Heart Research UK. PI: Prof Nicola Mutch. Co-I Prof Diana Gorog.
S100A8/A9 as a novel regulator of fibrinolysis in thromboinflammation. The British Heart Foundation. PI: Prof Nicola J Mutch, Co-Is Dr Julie Rayes and Dr Alexander Brill.
The role of vascular endothelial cells in dictating local fibrinolytic potential and thrombo-inflammatory complications. Medical Research Scotland. PI: Prof Nicola Mutch.
- Teaching
- Publications
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Page 1 of 4 Results 1 to 10 of 32
Colchicine acutely reduces liver-secreted inflammatory and metabolic proteins in blood
European Journal of Pharmacology, 178725Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.ejphar.2026.178725
Cancer-Associated Thrombosis (CAT); mechanisms and treatment options
Thrombosis Journal, vol. 23, no. 1, 116Contributions to Journals: ArticlesEndothelial cell source dictates the expression and release of fibrinolytic markers in a proinflammatory environment
Research and Practice in Thrombosis and Haemostasis, vol. 9, no. 5, 102929Contributions to Journals: ArticlesAcute obstetric coagulopathy is associated with excess plasmin generation and proteolysis of fibrinogen and factor V
Blood Advances, vol. 9, no. 11, pp. 2751-2762Contributions to Journals: ArticlesActivated platelets retain and protect most of their factor XIII-A cargo from proteolytic activation and degradation
Blood Advances, vol. 8, no. 19, pp. 5072–5085.Contributions to Journals: ArticlesFibrinogenolysis and fibrinolysis in Vaccine-induced Immune Thrombocytopenia and Thrombosis (VITT)
Journal of Thrombosis and Haemostasis, vol. 21, no. 12, pp. 3589-3596Contributions to Journals: ArticlesNovel therapeutics and emerging technology in haemostasis and thrombosis: highlights from the British society for haemostasis and thrombosis annual meeting
Frontiers in cardiovascular medicine, vol. 10, 1225243.Contributions to Journals: ArticlesPlatelet factor XIII-A regulates platelet function and promotes clot retraction and stability
Research and Practice in Thrombosis and Haemostasis, vol. 7, no. 5, 100200Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.rpth.2023.100200
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/b81ba3a8-6bed-444a-9c39-f7fc1dd4328c/download
- [ONLINE] View publication in Scopus
All tangled up: interactions of the fibrinolytic and innate immune systems
Frontiers in Medicine, vol. 10, 1212201Contributions to Journals: ArticlesEditorial: Women in Thrombosis
Frontiers in cardiovascular medicine, vol. 10, 1159938Contributions to Journals: Editorials
