M.Sc., Ph.D., AFHEA.,
Advanced Research Fellow
- About
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- Email Address
- amalraj.raja@abdn.ac.uk
- Telephone Number
- +44 (0)1224 437147
- Office Address
Telephone :01224-437147 Fax :01224 437857 Medical Statistics Team Division of Applied Health Sciences University of Aberdeen Polwarth Building Foresterhill ABERDEEN AB25 2ZD UK
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Edwin Amalraj Raja joined Public Health as a Research Fellow in Medical Statistics in May 2006. In 1983, Edwin Amalraj Raja got his undergraduate degree in Statistics from St.Joseph's College, Trichy, India and postgraduate degree in Statistics from Loyola College, Chennai, India.
Edwin Amalraj Raja completed advanced training on the application of Statistics in the Department of Biostatistics, Christian Medical College, Vellore. He worked in 'Advanced Center for Clinical Epidemiological Research and Training Centre' at Madras Medical College, Chennai. His work with the Tamil Nadu Government funded project on 'Epidemiology of Head Injury' led him to pursue and obtain his PhD in 'Biostatistical Application in the Prediction of Outcome of Severe Head Injury' from the Tamil Nadu M G R Medical University, Chennai, India.
Within Institute of Apllied Health Sciences (IAHS), Edwin Amalraj Raja is involved in the analysis of research projects, especially statistical modelling of longitudinal data, Statistical methods in Epidemiology, etc., He is also involved in teaching and training in Medical statistics organised by the Medical Statistics Team for staff and students of this University.
Memberships and Affiliations
- Internal Memberships
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Member of School Ethics Committee
Member of Health and Safety, School of Medicine
- External Memberships
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Statistical expert for North of Scotland Research Ethics Committee (NRES)
- Research
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Research Overview
Clinical Areas of Consulting Experience
Obstetric & Gynaecology Factors associated with Maternal complications, Maternal BMI & Offspring CVD , Mortality
Infertility Classification of infertility and demographic factors affecting fertility
Maternal Obesity Offspring developing CVD
Renal disease The relationship between renal function parameters and blood pressure
common Cancers Factors contributing to time to consult GP, provider delay & stage , Mortality
Diabetes Mellitus Prevalence, risk factors, incidence of complications, patients perception of their complication
Current Research
Methodological research interests
Prediction Modelling
Categorical data analysis
Statistical methods in Epidemiology
Analysis of repeated measures / Longitudinal Data Analysis / Multilevel Modeling
Structural Equation Modelling
Cubic spline analysis - Non-linear relationship between continuous variable and outcome
Survival analysis- Competing risks- recurrent events
Supervision
Looking for a PhD student
Title: The impact of duration of freezing of IVF embryos on pregnancy and perinatal outcomes – analysis of UK national data
Background of the research proposal:
IVF (in-vitro fertilisation) is the recommended treatment for couples with unresolved infertility. It involves mixing eggs and sperm to create embryos which are then cultured in the laboratory. Usually, the best embryo is then put back in the womb, while others can be frozen for future use. The use of frozen embryos has become popular across the globe in recent years, accounting for 41% of all IVF treatments in 2019 in UK. Although many embryos are frozen for short durations, others can be kept in the freezer for many months or years and it is believed that patients can use them at any time without affecting their chances of pregnancy rates or the health of their babies.
Aim: To find an association between the duration of embryo freezing and pregnancy and perinatal outcomes among couples treated for infertility
Dataset: This study will use information of treatments undertaken between 2000 and 2019 from the Human Fertilisation Embryology Authority (HFEA) database which holds data of all IVF treatments undertaken in the UK licensed clinics, to explore the impact of the duration of embryo freezing on IVF live birth rate and safety of children.
Exposure: the duration of embryo freezing
Outcomes: The main outcome measures are live birth, gestational age (preterm vs term), birthweight (small/large for gestational age vs normal for gestational age) and congenital anomalies. The results of the proposed research will provide patients and clinicians with the necessary information so that they can make informed choices in the future.
Statistical Analyses: The student is expected to come up with appropriate statistical methods and use machine learning techniques to address the research question or objective of the study.
Funding and Grants
Murchie P, Lisa I, Raja EA, Lee AJ. Do melanoma excised in primary care have different outcomes to those excised in secondary care? Friends of ANCHOR £10,000
David M, Bhattacharya S, Abha M, Raja EA. Perinatal outcomes of singletons born following in-vitro fertilisation: a comparison of different embryo transfer strategies using UK data. NHS Grampian Endowment .(submitted)
Mairead B, Sohinee B, Andrea W, Gail F, EA Raja and Ipek. Maternal Body Mass Index in pregnancy ana cardiometabolic risk in monozygotic and dizygotic twin offspring (submitted to Wellbeing of Women)
Sohinee B, Geraldine M, Rebecca R and EA Raja. Reproductive consequences of third and fourth degree perineal tears (submitted to CHSS)
- Teaching
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Teaching Responsibilities
Teaching in the Short courses organised by Medical Statistics Team
Introduction to Medical Statistics
Intermediate Statistics Course
B medical Science SPSS practicals II
M Sc Public Health practicals
- Publications
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Page 4 of 7 Results 31 to 40 of 66
Is frozen embryo transfer better for mothers and babies? Can cumulative meta-analysis provide a definitive answer?
Human Reproduction Update, vol. 24, no. 1, pp. 35-58Contributions to Journals: ArticlesDo patients' faces influence General Practitioners' cancer suspicions? A test of automatic processing of sociodemographic information
PloS ONE, vol. 12, no. 11, pp. 1-13Contributions to Journals: ArticlesIs initial excision of cutaneous melanoma by General Practitioners (GPs) dangerous? Comparing patient outcomes following excision of melanoma by GPs or in hospital using national datasets and meta-analysis
European Journal of Cancer, vol. 86, pp. 373-384Contributions to Journals: ArticlesGestational age at delivery of twins and perinatal outcomes, a Scottish cohort study
British Maternal & Fetal Medicine Society (BMFMS) 19th Annual Conference 2017, pp. 145-145Contributions to Journals: Abstracts- [ONLINE] DOI: https://doi.org/10.1111/1471-0528.14589
Obstetric and perinatal outcomes after either fresh or thawed frozen embryo transfer: an analysis of 112,432 singleton pregnancies recorded in the Human Fertilisation and Embryology Authority anonymized dataset
Fertility and Sterility, vol. 106, no. 7, pp. 1703-1708Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1016/j.fertnstert.2016.08.047
Maternal gestational weight gain and offspring's risk of cardiovascular disease and mortality
Heart, vol. 102, no. 18, pp. 1456-1463Contributions to Journals: ArticlesEffect of longer health service provider delays on stage at diagnosis and mortality in symptomatic breast cancer
Breast, vol. 24, no. 3, pp. 248-255Contributions to Journals: ArticlesMaternal Obesity During Pregnancy Associates With Premature Mortality and Major Cardiovascular Events in Later Life
Hypertension, vol. 66, no. 5, pp. 938-944Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1161/HYPERTENSIONAHA.115.05920
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/f02ea106-2693-42ca-b3b4-1d7be167f8b3/download
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/6c585f65-00a9-4878-a4c8-96d5b3f5d079/download
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/2910b6bf-f5b0-48d1-b9a1-c648a7250a39/download
Time from first presentation in primary care to treatment of symptomatic colorectal cancer: effect on disease stage and survival
British Journal of Cancer, vol. 111, no. 3, pp. 461-469Contributions to Journals: Articles- [ONLINE] DOI: https://doi.org/10.1038/bjc.2014.352
Authors' response to Diagnostic biopsy of melanoma: primary or secondary care?: Mortality and morbidity after initial diagnostic excision biopsy of cutaneous melanoma in primary versus secondary care
The British Journal of General Practice, vol. 64, no. 618, pp. 14Contributions to Journals: Comments and Debates- [ONLINE] DOI: https://doi.org/10.3399/bjgp14X676311