Professor Alison Murray

Professor Alison Murray
Professor Alison Murray
Professor Alison Murray

FRSE

Emeritus Professor

About

Biography

Professor Emerita (Radiology) with expertise in brain MRI correlates of cognitive ageing in the Aberdeen Birth Cohorts and in molecular brain imaging in TauRx clinical trials of novel therapeutics in Alzheimer's disease.

Consultant radiologist then honorary consultant NHS Grampian (1995-2020) with expertise in neuroradiology and molecular imaging. 

Qualifications

  • MB ChB (Hons) Medicine 
    1985 - University of Aberdeen 
  • MRCP Medicine 
    1988 - Royal College of Physicians & Surgeons of Glasgow 
  • FRCR Radiology 
    1992 - Royal College of Radiologists UK 
  • PhD Medical Sciences 
    2013 - University of Aberdeen 

    PhD Thesis November 2012 “Brain white matter hyperintensities: Correlates in normal ageing and relevance in Alzheimer’s disease.” Successfully defended January 2013

External Memberships

Fellow and council member of the Royal Society of Edinburgh

Chairperson Roland Sutton Academic Trust

Treasurer and Trustee Campaign for Evidence Based Healthcare

Trustee TENOVUS Scotland (Grampian Highlands and Islands)

Volunteer North-East Scotland Coastal Trust

Latest Publications

View My Publications

Prizes and Awards

FRSE (2017-)

Research

Supervision

Dr Sima Salarirad (2011) “The relative contributions of imaging biomarkers of cerebrovascular and Alzheimer’s diseases to cognitive ageing”

Dr Moses Olufemi Sokunbi (2011) “Functional MRI entropy measurements of brain complexity”

Dr Ivan Roijals Miras (2012) “Information processing speed and information flow in the ageing brain”

Dr Dorota Chapko (2016) “Life-course determinants of resilience to cognitive ageing”

Dr Maryam Hashim (2016) 3rd supervisor “Optimisation of MRI for neuroimaging in inflammatory diseases”

Dr Maria Goni (2018) 3rd supervisor “Imaging correlates of fatigue in inflammatory disease”

Dr Clarisse De Vries – (2020) “Early life and life-course predictors of brain entropy and functional connectivity.

Dr Jennifer Waymont  (2020) “Automated detection of brain lesions in the Aberdeen Children of the 1950s and analysis of lifecourse determinants”

Dr Shaun Stone (2021) “Prediction models of dementia risk from brain MR images and proxies of cognitive reserve”

Dr Mina Kherzian (2021) “Investigating the role of polypharmacy in brain ageing, and cognitive, physical and emotional impairment in three well characterised cohort studies in Aberdeen”

Dr Shailendra Mohan Tripathi (2021) “Machine learning in classification of Alzheimer’s disease diagnosis and response to treatment”

Publications

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  • Increased diastolic blood pressure is associated with MRI biomarkers of dementia-related brain pathology in normative ageing

    McNeil, C. J., Myint, P. K., Sandu-Giuraniuc, A., Potter, J. F., Staff, R., Whalley, L. J., Murray, A. D.
    Age and Ageing, vol. 47, no. 1, pp. 95-100
    Contributions to Journals: Articles
  • ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

    Bihlmeyer, N. A., Brody, J. A., Smith, A. V., Warren, H. R., Lin, H., Isaacs, A., Liu, C., Marten, J., Radmanesh, F., Hall, L. M., Grarup, N., Mei, H., Müller-Nurasyid, M., Huffman, J. E., Verweij, N., Guo, X., Yao, J., Li-Gao, R., van den Berg, M., Weiss, S., Prins, B. P., van Setten, J., Haessler, J., Lyytikäinen, L., Li, M., Alonso, A., Soliman, E. Z., Bis, J. C., Austin, T., Chen, Y. I., Psaty, B. M., Harrris, T. B., Launer, L. J., Padmanabhan, S., Dominiczak, A., Huang, P. L., Xie, Z., Ellinor, P. T., Kors, J. A., Campbell, A., Murray, A. D., Nelson, C. P., Tobin, M. D., Bork-Jensen, J., Hansen, T., Pedersen, O., Linneberg, A., Sinner, M. F., Peters, A., Waldenberger, M., Meitinger, T., Perz, S., Kolcic, I., Rudan, I., de Boer, R. A., van der Meer, P., Lin, H. J., Taylor, K. D., de Mutsert, R., Trompet, S., Jukema, J. W., Maan, A. C., Stricker, B. H. C., Rivadeneira, F., Uitterlinden, A., Völker, U., Homuth, G., Völzke, H., Felix, S. B., Mangino, M., Spector, T. D., Bots, M. L., Perez, M., Raitakari, O. T., Kähönen, M., Mononen, N., Gudnason, V., Munroe, P. B., Lubitz, S. A., van Duijn, C. M., Newton-Cheh, C. H., Hayward, C., Rosand, J., Samani, N. J., Kanters, J. K., Wilson, J. G., Kääb, S., Polasek, O., van der Harst, P., Heckbert, S. R., Rotter, J. I., Mook-Kanamori, D. O., Eijgelsheim, M., Dörr, M., Jamshidi, Y., Asselbergs, F. W., Kooperberg, C., Lehtimäki, T., Arking, D. E., Sotoodehnia, N.
    Circulation. Genomic and precision medicine, vol. 11, no. 1, e001758
    Contributions to Journals: Articles
  • Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease

    McCartney, D. L., Stevenson, A. J., Walker, R. M., Gibson, J., Morris, S. W., Campbell, A., Murray, A. D., Whalley, H. C., Porteous, D. J., McIntosh, A. M., Evans, K. L., Deary, I. J., Marioni, R. E.
    Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, vol. 10, pp. 429-437
    Contributions to Journals: Articles
  • Life-course determinants of cognitive reserve (CR) in cognitive aging and dementia: a systematic literature review

    Chapko, D., McCormack, R., Black, C., Staff, R., Murray, A.
    Aging & Mental Health, vol. 22, no. 8, pp. 915-926
    Contributions to Journals: Articles
  • Neural indicators of fatigue in chronic diseases: A systematic review of MRI studies

    Goni, M., Basu, N., Murray, A. D., Waiter, G. D.
    Diagnostics, vol. 8, no. 3, 42
    Contributions to Journals: Articles
  • A Review of Frailty Syndrome and Its Physical, Cognitive and Emotional Domains in the Elderly

    Khezrian, M., Myint, P. K., McNeil, C. J., Murray, A. D.
    Geriatrics, vol. 2, no. 4, 36
    Contributions to Journals: Articles
  • Commentary on: Association of imaging abnormalities of the subcallosal septal area with Alzheimer's disease and mild cognitive impairment

    Murray, A. D.
    Clinical Radiology, vol. 72, no. 11, pp. 923-924
    Contributions to Journals: Comments and Debates
  • Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

    Clarke, T., Adams, M. J., Davies, G., Howard, D. M., Hall, L. S., Padmanabhan, S., Murray, A. D., Smith, B. H., Campbell, A., Hayward, C., Porteous, D. J., Deary, I. J., McIntosh, A. M.
    Molecular Psychiatry, vol. 22, no. 10, pp. 1376-1384
    Contributions to Journals: Articles
  • Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder

    Zeng, Y., Navarro, P., Shirali, M., Howard, D. M., Adams, M. J., Hall, L. S., Clarke, T. K., Thomson, P. A., Smith, B. H., Murray, A., Padmanabhan, S., Hayward, C., Boutin, T., MacIntyre, D. J., Lewis, C. M., Wray, N. R., Mehta, D., Penninx, B. W., Milaneschi, Y., Baune, B. T., Air, T., Hottenga, J. J., Mbarek, H., Castelao, E., Pistis, G., Schulze, T. G., Streit, F., Forstner, A. J., Byrne, E. M., Martin, N. G., Breen, G., Müller-Myhsok, B., Lucae, S., Kloiber, S., Domenici, E., Deary, I. J., Porteous, D. J., Haley, C. S., McIntosh, A. M., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
    Biological Psychiatry, vol. 82, no. 5, pp. 312-321
    Contributions to Journals: Articles
  • Organisation of cortical thickness networks in Alzheimer’s disease and behavioural variant frontotemporal dementia across brain lobes

    Vuksanovic, V., Staff, R., Ahearn, T., Bentham, P., Murray, A. D., Wischik, C. M.
    6th Cambridge Neuroscience Symposium
    Contributions to Conferences: Abstracts
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