Dr Andrew McEwan | The University of Aberdeen

Dr Andrew McEwan

Advanced Research Fellow

About

School/Department: School of Medicine, Medical Sciences and Nutrition

Publications

Page 1 of 2 Results 1 to 10 of 19

Exploring the roles of conserved context-dependent cis-regulatory elements (ccdCREs) in multicellularity, human health and disease
2025 - Published
McEwan, A. R., Rattray, A., Hutchings, G., Hay, E. A., Murgatroyd, C., MacKenzie, A.
FEBS Journal, vol. 292, no. 23, pp. 6163-6181
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1111/febs.70174
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/2c996e73-a60d-4020-a024-0fe503ad3ce7/download
Inhibitors of PTP1B/NCK1 interaction and methods of making and using same
2024 - Published
Delibegovic, M., Dall'Angelo, S., Hamer, M. M., Dekeryte, R., McEwan, A. R., Greig, I.
Patents: Patents
- [ONLINE] https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2024178250&_cid=P10-M0FOXW-70692-1
An ancient polymorphic regulatory region within the BDNF gene associated with obesity modulates anxiety-like behaviour in mice and humans
2024 - Published
McEwan, A. R., Hing, B., Erickson, J. C., Hutchings, G., Urama, C., Norton-Hughes, E., D'Ippolito, M., Berry, S., Delibegovic, M., Grassmann, F., MacKenzie, A.
Molecular Psychiatry, vol. 29, no. 3, pp. 660-670
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1038/s41380-023-02359-7
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/b8b46c95-65c6-480e-9fa8-ae3676605765/download
Context-dependant enhancers as a reservoir of functional polymorphisms and epigenetic markers linked to alcohol use disorders and comorbidities
2022 - Published
MacKenzie, A., Hay, E. A., McEwan, A. R.
Addiction neuroscience, vol. 2, 100014
Contributions to Journals: Review articles
- [ONLINE] DOI: https://doi.org/10.1016/j.addicn.2022.100014
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/e855b5d7-dcca-4363-bcad-1e3f1ecbd2a2/download
CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake
2021 - Published
McEwan, A. R., Davidson, C., Hay, E., Turnbull, Y., Erickson, J. C., Marini, P., Wilson, D., McIntosh, A., Adams, M. J., Murgatroyd, C., Barrett, P., Delibegovic, M., Clarke, T., MacKenzie, A.
Molecular Psychiatry, vol. 26, pp. 2263–2276
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1038/s41380-020-0707-7
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/e9355a7d-6af0-47aa-8a0d-fa85eaa84f50/download
- [ONLINE] View publication in Scopus
The anxiety and ethanol intake controlling GAL5.1 enhancer is epigenetically modulated by, and controls preference for, high-fat diet
2021 - Published
McEwan, A., Erickson, J. C., Davidson, C., Heijkoop, J., Turnbull, Y., Delibegovic, M., Murgatroyd, C., MacKenzie, A.
Cellular and Molecular Life Sciences, vol. 78, no. 6, pp. 3045-3055
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1007/s00018-020-03705-6
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/790a7d4f-443b-4c16-bcf7-713c4ef74e76/download
- [ONLINE] View publication in Scopus
Perspective: Quality Versus Quantity; Is It Important to Assess the Role of Enhancers in Complex Disease from an In Vivo Perspective?
2020 - Published
McEwan, A. R., MacKenzie, A.
International Journal of Molecular Sciences, vol. 21, no. 21, 7856
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.3390/ijms21217856
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/19f61556-ae2f-4175-a865-e7b0df699f5e/download
- [ONLINE] View publication in Scopus
Disease associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue specific activity of the cannabinoid‐1 receptor gene promoter; implications for cannabinoid pharmacogenetics
2020 - Published
Hay, E. A., Cowie, P., McEwan, A. R., Ross, R., Pertwee, R. G., MacKenzie, A.
Human Mutation, vol. 41, no. 1, pp. 291-298
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1002/humu.23931
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/7909f0e8-3d91-45d2-8fdb-00370ec15102/download
- [ONLINE] View publication in Scopus
Disruption of an enhancer associated with addictive behaviour within the cannabinoid receptor-1 gene suggests a possible role in alcohol intake, cannabinoid response and anxiety-related behaviour
2019 - Published
Hay, E. A., McEwan, A., Wilson, D., Barrett, P., D'Agostino, G., Pertwee, R. G., MacKenzie, A.
Psychoneuroendocrinology, vol. 109, pp. 104407
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1016/j.psyneuen.2019.104407
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/d4cca040-cf9b-4d67-a10f-9a21f470dae1/download
- [ONLINE] View publication in Scopus
- [ONLINE] View publication in Mendeley
A Blind Test of Computational Technique for Predicting the Likelihood of Peptide Sequences to Cyclize
2017 - Published
Booth, J., Alexandru-Crivac, C., Rickaby, K. A., Nneoyiegbe, A. F., Umeobika, U., McEwan, A. R., Trembleau, L., Jaspars, M., Houssen, W. E., Shalashilin, D. V.
The Journal of Physical Chemistry Letters, vol. 8, no. 10, pp. 2310-2315
Contributions to Journals: Articles
- [ONLINE] DOI: https://doi.org/10.1021/acs.jpclett.7b00848
- [OPEN ACCESS] http://aura.abdn.ac.uk/bitstreams/5ec69daa-84b9-417b-94d2-3c2c42fc8d82/download

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Exploring the roles of conserved context-dependent cis-regulatory elements (ccdCREs) in multicellularity, human health and disease

Inhibitors of PTP1B/NCK1 interaction and methods of making and using same

An ancient polymorphic regulatory region within the BDNF gene associated with obesity modulates anxiety-like behaviour in mice and humans

Context-dependant enhancers as a reservoir of functional polymorphisms and epigenetic markers linked to alcohol use disorders and comorbidities

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

The anxiety and ethanol intake controlling GAL5.1 enhancer is epigenetically modulated by, and controls preference for, high-fat diet

Perspective: Quality Versus Quantity; Is It Important to Assess the Role of Enhancers in Complex Disease from an In Vivo Perspective?

Disease associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue specific activity of the cannabinoid‐1 receptor gene promoter; implications for cannabinoid pharmacogenetics

Disruption of an enhancer associated with addictive behaviour within the cannabinoid receptor-1 gene suggests a possible role in alcohol intake, cannabinoid response and anxiety-related behaviour

A Blind Test of Computational Technique for Predicting the Likelihood of Peptide Sequences to Cyclize

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Patents