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Undergraduate Pharmacology 2022-2023

PA3004: BIOCHEMICAL PHARMACOLOGY AND TOXICOLOGY

30 credits

Level 3

First Term

  • Biochemical pharmacology and toxicology is a broad ranging course covering many fundamental aspects of pharmacology. It lays appropriate foundations upon which advanced Pharmacological understanding is developed.
  • Key aspects are:
    - critical concepts of pharmacological and toxicological relevance are covered in-depth at a molecular and biochemical level, with the ultimate significance to the human organism also studied
    - a modern and relevant practical thread (partly funded by the British Pharmacological Society) permits application of lecture materials, and enhances employability through development of relevant core practical skills
    - research-led special topics are also embedded where the materials studied are put in context through teaching driven by recent medical research discoveries

PA3802: MECHANISMS OF DISEASE AND PRINCIPLES OF CHEMOTHERAPY

15 credits

Level 3

Second Term

The course is designed to give the students a basic understanding of the mechanisms of disease.

  • by understanding the process of a disease we can find ways of both treating it and/or preventing it;
  • this course uses the examples of cancer, infectious disease and inflammatory disease to illustrate this;
  • the factors leading to or causing the disease will be described;
  • using this knowledge the way in which the drugs used to treat the disease work will be discussed;
  • problems that arise from drug treatment such as drug resistance will also be covered

PA4005: MOLECULAR PHARMACOLOGY

15 credits

Level 4

First Term

  • this course provides topical reviews of receptor diversity, expression and signalling in the contexts of both basic science and applications in the treatments of disease and ill health;
  • modern and developing aspects of pharmacology are linked with proteomics/ genomics, therapeutics and methods of drug discovery;
  • specialist emerging aspects of molecular pharmacology including biased ligands and receptor trafficking and their role in disease will be studied in detail;
  • in addition to lectures the course includes advanced data analysis-based tutorials and data presentation which will enhance transferable skills and add to graduate portfolios

PA4303: CURRENT TOPICS IN PHARMACOLOGICAL RESEARCH

15 credits

Level 4

First Term

The course aims to develop an understanding of pharmacological targeting and molecular toxicology at an advanced level. The learning outcomes are:

  • To gain knowledge of drug-induced toxicity including organ specific toxicity, oxidative stress and the role of drug transport
  • To develop advanced understandings of the processes surrounding pharmacological drug design and molecular targeting using specific examples
  • To develop knowledge of the processes involved in cell death including apoptosis, autophagy and necrosis
  • To enhance understanding of the use of biomarkers in pharmacology and toxicology
  • To develop advanced knowledge of molecular carcinogensis (genotoxic and non-genotoxic)

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