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MB5519: IMMUNOGENETICS (2018-2019)

Last modified: 22 May 2019 17:07

Course Overview

The genetic basis of self/non-self discrimination underlies all immune responses and can influence disease susceptibility at the level of both individual and populations. This course addresses this topic through lectures from research active experts in the main areas covered.

The course Workshop involves students delivering a poster presentation on a course-related topic, providing the opportunity for students to practice presentation skills before undertaking the Masters Research project later in the academic year.

Course Details

Study Type Postgraduate Level 5
Session Second Sub Session Credit Points 15 credits (7.5 ECTS credits)
Campus None. Sustained Study No
  • Dr Frank Ward
  • Dr Isabel Crane

What courses & programmes must have been taken before this course?

  • Either MSc Immunology (Studied) or MSc Genetics (Studied)
  • Any Postgraduate Programme (Studied)

What other courses must be taken with this course?


What courses cannot be taken with this course?


Are there a limited number of places available?


Course Description


The course will allow an understanding of how genetics defines ‘yourself’ to your immune system; how genetic mechanisms such as recombination and point mutation create diversity and specificity of immune effector molecules; how genetic variation in certain genes of the immune system can influence susceptibility or resistance to both autoimmune and infectious disease; and how genetics can inform clinical therapies for a range of diseases including cancer.

Learning outcomes

At the end of this course students should be familiar with the following:

· The genetic basis of immunological self

· The evolution of mammalian immune systems

· How genetic variation at the individual and population levels results in susceptibility or resistance to disease

· Genetic mechanisms generating T cell receptor and antibody diversity

· How genetic analysis can inform future attempts at immunotherapy

In light of Covid-19 this information is indicative and may be subject to change.

Contact Teaching Time

Information on contact teaching time is available from the course guide.

Teaching Breakdown

More Information about Week Numbers

In light of Covid-19 and the move to blended learning delivery the assessment information advertised for second half-session courses may be subject to change. All updates for second-half session courses will be actioned in advance of the second half-session teaching starting. Please check back regularly for updates.

Summative Assessments

Continuous assessment (50% - flow cytometry and group presentation) and examinations (50% - multiple choice examination questions)

Formative Assessment

There are no assessments for this course.



Course Learning Outcomes


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