Last modified: 22 May 2019 17:07
|Session||First Sub Session||Credit Points||15 credits (7.5 ECTS credits)|
Topics include absorption, distribution, metabolism, excretion and transport of drugs.
Human drug metabolism - cytochrome P450.
Induction/inhibition of cytochrome P450.
Identification of cytochrome P450 and transporters at an early stage in drug discovery.
Mechanisms of drug induced toxicity: reactive metabolites; cytoprotective mechanisms; agents conferring protection against drug toxicity - clinical applications; mechanisms of cell death; apoptosis and necrosis.
Immunotoxicology and risk assessment.
Pathology of drug toxicity.
Haematological indices of drug toxicity.
Information on contact teaching time is available from the course guide.
Individual lab report (20%); Editorial (15%); Debate (15%); Examination (50%).
There are no assessments for this course.