Session Summary
Learning objectives
By the end of this session you will be able to:
- Describe the typical concentration-time curve for a drug with first-order kinetics
- Explain the importance of zero-order (saturation) kinetics
- Define clearance and half-life
- Define bioavailability
Further reading and activities
Refer to the following texts for additional information:
- Waller DG, Renwick AG, Hillier K, eds. Medical Pharmacology and Therapeutics. 3rd Edition. Oxford: Elsevier Saunders, 2009.
- Rowland M, Tozer T. Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications. 4th Edition. Philadelphia: Lippincott, Williams and Wilkins, 2010.
