Research

The Academic Urology Unit has three main themes: Cancer, Benign Prostatic Diseases and Pelvic Floor Dysfunction. The unit has four inter-related research activities: Trials & Large Observational Studies, Systematic reviews, Economic evaluations and Patient-centred programme of work (Information & Decision making, Psychological preparation for surgery, and Service development).

Current Programmes of work include:

Trials and Large Observational Studies

OTIS Study (Outcome After Transposed Segment Surgery), funded by BUPA Foundation, is a prospective multicentre study recruiting from 18 UK centres.  OTIS has now stopped recruiting and the final report is currently being written.

The CATHETER Trial is investigating the benefit of short-term catheters in preventing symptomatic urinary tract infection in 23 UK centres. CATHETER has now stopped recruiting and the final report is currently being written.

SUSPEND is a newly funded multicentre trial of medical expulsive therapy to facilitate passage of ureteric stones and started recruiting in January 2011.  The Trial Manager is Kath Starr

Both the CATHETER Trial and SUSPEND are funded by NIHR.

Systematic Reviews

Systematic review and economic modelling of the relative clinical benefit and cost-effectiveness of laparoscopic surgery and robotic surgery for removal of the prostate in men with localised prostate cancer: The study aims to determine the clinical effectiveness, safety and cost-effectiveness of robotic radical prostatectomy compared with laparoscopic radical prostatectomy in the treatment of patients with localised prostate cancer. A secondary objective is to determine the influence of the learning curve on estimates of effectiveness and safety for each procedure. The study is funded by the NHS National Institute for Health Research Health Technology Assessment Programme and the results will inform NICE and other healthcare regulatory bodies.

Cochrane Incontinence Group: The Academic Urology Unit is home to the editorial base of the Cochrane Incontinence Group editorial base, funded by the Department of Health. The Cochrane Incontinence Group is a Collaborative Review Group (CRG) of the Cochrane Collaboration, an international organisation dedicated to informing those who provide or receive health care on the best available evidence. The Group has over 60 published reviews in the Cochrane Library. The Joint Co-ordinating editors are Professor James N'Dow and Professor Cathryn Glazener. The Managing Editor is Imran Omar. The Trials Search Co-ordinator is Sheila Wallace and Editorial Assistant to the Group is Suzanne MacDonald.Urological Cancer Care Programme Systematic Review Group:

For more information, please visit the UCAN website

Patient Centred Programmes of Work

Urological Cancer Care Programme: The five main urological cancers are prostate, kidney, bladder, testicular and penile.  They mainly affect men, although women can suffer from kidney and bladder cancers.  Urological cancers are more common than many people realise, and account for 1 in 3 of all cancers in men and 1 in 5 of all cancers in men and women. This programme of research has three key strands: Understanding the information needs and decision making of those diagnosed with urological cancer; Addressing uncertainties in urological cancer care; Delivering support to those diagnosed with urological cancer. This programme is managed by Dr Sara Jane MacLennan.

Previous programmes of work include:

MAPS (Men After Prostate Surgery), funded by the NHS Health Technology Assessment Programme, is a national multicentre trial of pelvic floor muscle training for incontinence after prostate surgery recruiting from 30 UK centres.  This trial is now closed to recruitment and is in the process of reporting the findings.

The Academic Urology Unit has secured funding from other sources including MacMillan and Big Lottery.