Last modified: 22 May 2019 17:07
Human genetics has undergone a revolution over the last decade, driven by technological innovations that have given us an unprecedented insight into the genetic diversity of our species. This course will explore how this information is used to determine the role of genetic variation in human health and disease.
|Session||Second Sub Session||Credit Points||15 credits (7.5 ECTS credits)|
The following topics will be covered: Hardy Weinberg Equilibrium; Genetic Drift; Linkage Disequilibrium; Selection; Admixture; Inbreeding; Genome Wide Association Studies; Common Versus Rare/Unique Genetic Variants in Disease; Archaic Human Genomes.
The aim of this course is to provide an in-depth understanding of human genetics, with a special emphasis on recent findings from molecular population genetics. The course demonstrates how new insights into human biology and medicine have been obtained through the availability of multiple human genome sequences, and how these are shedding light on the evolution of important human traits. The student will understand the importance played by genome sequence data derived from human populations and individuals, including insights into how this has impacted our understanding of disease susceptibility, environmental adaptions, and the role of introgression between anatomically modern humans and other hominins. The student will gain an appreaciation of the forces, both directed and random, that shape the formation and reformation of the human genome.
Information on contact teaching time is available from the course guide.
The course consists of an essay-based examination (50%), a set of online problems (20%) and a workshop report (30%).
Resit will be oral exam - examiners = course coordinator plus a programme coordinator
Oral exam will assess whether the student has achieved the learning outcomes of the course.
There will be two formative assessments based on the lecture material to allow students to monitor their performance.
Written feedback will be provided for the in course, summative assessments and formative assessment exercises.