Last modified: 22 May 2019 17:07
An exciting course that brings a student right up to date with the most modern bioinformatics, genome assembly and annotation technology. You, the student, will isolate a novel bacterium from the environment and purify its DNA. This will be whole genome sequenced, and you will then assemble your own bacterial genome and functionally annotate it, taught by expert bioinformaticians from our Centre for Genome-Enabled Biology and Medicine. Your analysis will enable you to make identifications of the species you have isolated, its metabolic and environmental responses, growth constraints and regulation, cell surface markers and antibiotic resistance, producing a full inventory of genes and their presumptive functions. Overall the course prepares a student for future employment in a biosciences workplace where genome sequencing and annotation is becoming an every-day tool of modern biotechnology.
|Session||Second Sub Session||Credit Points||15 credits (7.5 ECTS credits)|
This course will take students through the exciting and challenging process of analysing the sequence of a bacterial genome that they themselves have identified and purified DNA from in semester 1. If you want to work on your own data during this course you need to do BT5014 in semester 1. However, this is not mandatory and if you have not studied BT5014, bacterial genome sequencing reads will be provided to you to use in MB5522. The course will teach students how to assemble a genome, quality control the output, annotate genes, and carry out functional gene analysis using modern biotechnology, to produce an assembled genome and full inventory of the genes of a novel bacterial isolate.
Information on contact teaching time is available from the course guide.
Project report (100%).
Resit: viva with 2 academic staff on the knowledge and understanding of the student on the subject of their practical report - this practical report assesses all of the learning outcomes of the course.
We will carry out 2 x MCQ formative assessments during workshop or tutorial. These have 0% weighting.
Feedback (free text and rubric) provided on the project report via on-line marking platforms within MyAberdeen.