Last modified: 22 May 2019 17:07
Pharmacokinetics describe “what the body does to a drug” and thus is a central feature of applied pharmacology. The course will develop an understanding of the role that pharmacokinetics play in all aspects of drug administration, distribution, metabolism and excretion and how these effects can be modelled and predicted graphically and mathematically. Such modelling is a fundament of therapeutic regimen design, drug development, clinical pharmacology and drug safety and will be considered within all of these contexts providing a broad and relevant appreciation of the importance of pharmacokinetics to the pharmacologist
|Session||Second Sub Session||Credit Points||15 credits (7.5 ECTS credits)|
The course combines lecture-based learning, with tutorials and laboratory practicals, aimed to enhance understanding of pharmacokinetic principles by combining theory, practice and application.
Lectures will focus on the pharmacokinetic considerations of single intravenous (IV) or single oral administration, and also multiple IV and oral administration with contextualised tutorials integrated to reinforce and demonstrate key lecture principles. There will be additional tutorials using online support tools, as an added means of teaching support.
The course will also consider the importance of pharmacokinetics from a clinical perspective and also a drug development/design angle to deliver an appreciation of the professional use of these skills.
A laboratory project will provide a further dimension to explore pharmacokinetics where a model system will be used to simulate single IV and single oral administration of a drug, with generated data then compared by applying the skills developed throughout the course.
Information on contact teaching time is available from the course guide.
Assessed through practical report (20%) and a written exam (80%).
Tutorials involve formative problems and exercises to help students to develop and understanding of how to apply the concepts.
Significant feedback provided informally during tutorials and practical. Online feedback provided for laboratory report.