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BT5509: BIOLOGIC DRUG DISCOVERY (2018-2019)

Last modified: 22 May 2019 17:07


Course Overview

Biologic therapies represent one of the most important and novel areas of drug discovery in the 21st century. The aim of this course is to provide an insight into the success of protein, peptide or antibody based biologic therapies and to examine how this exciting new area will develop over the next decade.

Course Details

Study Type Postgraduate Level 5
Session Second Sub Session Credit Points 15 credits (7.5 ECTS credits)
Campus None. Sustained Study No
Co-ordinators
  • Dr Frank Ward

What courses & programmes must have been taken before this course?

  • Any Postgraduate Programme (Studied)

What other courses must be taken with this course?

None.

What courses cannot be taken with this course?

None.

Are there a limited number of places available?

No

Course Description

Large protein or peptide based therapeutics, or biologics have an increasing influence on our ability to treat a range of complex disorders ranging from rare autoimmune diseases, through allergy and even difficult to treat cancers. This is an exciting, rapidly expanding area with several novel therapies being introduced each year. In most cases, the introduction of a novel biologic will offer new potential for treating a particular disease. Development of a biologic is difficult, but the rewards if successful are huge, with sales far in excess of $1billion per annum.

Biologics are different from small molecule drug options because typically they are designed with strong prior knowledge based around how they may alter the disease outcome. The course will address the challenges that specifically face developing biologic therapies including issues around clinical trial design, patient safety and legal issues with regard to developing biosimilar products.

We will use real clinical examples to examine a range of different types of biologic encompassing functional proteins, antibodies and peptides. There will be a strong focus on novel therapeutics that are currently close to market.

Degree Programmes for which this Course is Prescribed

  • MSc Bio-Business and Medical Sciences
  • MSc Drug Discovery and Development
  • MSc Immunology
  • Master Of Science In Immunology And Immunotherapy

Contact Teaching Time

16 hours

This is the total time spent in lectures, tutorials and other class teaching.

Teaching Breakdown

  • 1 Lecture during University weeks 25, 31
  • 2 Lectures during University weeks 26 - 28
  • 1 Tutorial during University weeks 27 - 28, 31

More Information about Week Numbers


Summative Assessments

Group presentation (50%), 1 essay (50%).

Formative Assessment

There are no assessments for this course.

Feedback

Feedback is provided on student presentations

Course Learning Outcomes

None.

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