Last modified: 28 Jun 2018 10:27
The genetic basis of self/non-self discrimination underlies all immune responses and can influence disease susceptibility at the level of both individual and populations. This course addresses this topic through lectures from research active experts in the main areas covered.
The course Workshop involves students delivering a poster presentation on a course-related topic, providing the opportunity for students to practice presentation skills before undertaking the Masters Research project later in the academic year.
|Session||Second Sub Session||Credit Points||15 credits (7.5 ECTS credits)|
The course will allow an understanding of how genetics defines ‘yourself’ to your immune system; how genetic mechanisms such as recombination and point mutation create diversity and specificity of immune effector molecules; how genetic variation in certain genes of the immune system can influence susceptibility or resistance to both autoimmune and infectious disease; and how genetics can inform clinical therapies for such disease conditions.
At the end of this course students should be familiar with the following:
· The genetic basis of immunological self
· The evolution of mammalian immune systems
· How genetic variation at the individual and population levels results in susceptibility or resistance to disease
· Genetic mechanisms generating T cell receptor and antibody diversity
· How genetic analysis can inform future attempts at immunotherapy
This is the total time spent in lectures, tutorials and other class teaching.