B3 White Blood Cells

White Blood Cells:

  • White blood cells, also known as leucocytes, are easily defined by the presence of a nucleus
  • They represent <1 % of the cells circulating in normal peripheral blood
  • There are several types of white blood cell but they have some common features:
    • Unlike red blood cells, they only use the blood as a means of transport around the body
    • This is generally from their site of production to their site of function
    • They have the ability to move by amoeboid type locomotion
    • This allows them to leave the cardiovascular system - usually in post-capillary venules to enter connective tissue spaces where they function
    • They are generally involved in immune type responses
  • In a healthy individual the % of each type of white blood cell falls within a normal range (details will be given in subsequent pages for each type of white blood cell)
  • When the % of each cell type falls outwith the normal range it provides a valuable indicator of disease

White Blood Cell Categories:

  • White blood cells fall into two main categories with sub-categories, these are:
  • Granular leucocytes

    • Neutrophils
    • Eosinophils
    • Basophils

    Agranular leucocytes

    • Lymphocytes
    • Monocytes